Search Results - "Pahil, Karanbir S"

Structural basis of unidirectional export of lipopolysaccharide to the cell surface by Owens, Tristan W., Taylor, Rebecca J., Pahil, Karanbir S., Bertani, Blake R., Ruiz, Natividad, Kruse, Andrew C., Kahne, Daniel

“…Gram-negative bacteria are surrounded by an inner cytoplasmic membrane and by an outer membrane, which serves as a protective barrier to limit entry of many…”
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Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport by Simpson, Brent W, Pahil, Karanbir S, Owens, Tristan W, Lundstedt, Emily A, Davis, Rebecca M, Kahne, Daniel, Ruiz, Natividad

“…ATP-binding cassette (ABC) transporters constitute a large family of proteins present in all domains of life. They are powered by dynamic ATPases that harness…”
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Novobiocin Enhances Polymyxin Activity by Stimulating Lipopolysaccharide Transport by Mandler, Michael D, Baidin, Vadim, Lee, James, Pahil, Karanbir S, Owens, Tristan W, Kahne, Daniel

“…Gram-negative bacteria are challenging to kill with antibiotics due to their impenetrable outer membrane containing lipopolysaccharide (LPS). The polymyxins,…”
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A new antibiotic traps lipopolysaccharide in its intermembrane transporter by Pahil, Karanbir S., Gilman, Morgan S. A., Baidin, Vadim, Clairfeuille, Thomas, Mattei, Patrizio, Bieniossek, Christoph, Dey, Fabian, Muri, Dieter, Baettig, Remo, Lobritz, Michael, Bradley, Kenneth, Kruse, Andrew C., Kahne, Daniel

“…Gram-negative bacteria are extraordinarily difficult to kill because their cytoplasmic membrane is surrounded by an outer membrane that blocks the entry of…”
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Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors by Zhang, Ge, Baidin, Vadim, Pahil, Karanbir S., Moison, Eileen, Tomasek, David, Ramadoss, Nitya S., Chatterjee, Arnab K., McNamara, Case W., Young, Travis S., Schultz, Peter G., Meredith, Timothy C., Kahne, Daniel

“…New drugs are needed to treat gram-negative bacterial infections. These bacteria are protected by an outer membrane which prevents many antibiotics from…”
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Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter by Pahil, Karanbir S., Gilman, Morgan S. A., Baidin, Vadim, Clairfeuille, Thomas, Mattei, Patrizio, Bieniossek, Christoph, Dey, Fabian, Muri, Dieter, Baettig, Remo, Lobritz, Michael, Bradley, Kenneth, Kruse, Andrew C., Kahne, Daniel

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Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter by Pahil, Karanbir S., Gilman, Morgan S. A., Baidin, Vadim, Clairfeuille, Thomas, Mattei, Patrizio, Bieniossek, Christoph, Dey, Fabian, Muri, Dieter, Baettig, Remo, Lobritz, Michael, Bradley, Kenneth, Kruse, Andrew C., Kahne, Daniel

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