Search Results - "Pagnozzi, Martin J"

CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents by Menniti, Frank S, Pagnozzi, Martin J, Butler, Paul, Chenard, Bertrand L, Jaw-Tsai, Sarah S, Frost White, W

“…(1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol (CP-101,606) is a noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors…”
Get full text

Quinazolin-4-one α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonists:  Structure−Activity Relationship of the C-2 Side Chain Tether by Chenard, Bertrand L, Welch, Willard M, Blake, James F, Butler, Todd W, Reinhold, Anthony, Ewing, Frank E, Menniti, Frank S, Pagnozzi, Martin J

“…A series of 6-fluoro-3-(2-chlorophenyl)quinazolin-4-ones has been prepared, which contains a 2-fluorophenyl ring attached to C-2 by a variety of two-atom…”
Get full text

(3R,4S)-3-[4-(4-Fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol:  A Conformationally Restricted Analogue of the NR2B Subtype-Selective NMDA Antagonist (1S,2S)-1-(4-Hydroxyphenyl)-2- (4-hydroxy-4-phenylpiperidino)-1-propanol by Butler, Todd W, Blake, James F, Bordner, Jon, Butler, Paul, Chenard, Bertrand L, Collins, Mary A, DeCosta, Debra, Ducat, Mary J, Eisenhard, Michael E, Menniti, Frank S, Pagnozzi, Martin J, Sands, Steven B, Segelstein, Barbara E, Volberg, Walter, White, W. Frost, Zhao, Dayao

“…(1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol (CP-101,606, 1) is a recently described antagonist of N-methyl-d-aspartate (NMDA)…”
Get full text

P2-005 Gamma secretase inhibitor-induced coat color changes in a novel animal model, the degu (Octodon degus) by Pagnozzi, Martin J., Dunstan, Robert, Ryan, Ann, Payette, Mary, Tate, Barbara

Get full text

Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists by Menniti, F S, Chenard, B L, Collins, M B, Ducat, M F, Elliott, M L, Ewing, F E, Huang, J I, Kelly, K A, Lazzaro, J T, Pagnozzi, M J, Weeks, J L, Welch, W M, White, W F

“…The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor is an ionotropic glutamate receptor that mediates fast excitatory synaptic…”
Get more information

Conantokin-G: a novel peptide antagonist to the N-methyl-D-aspartic acid (NMDA) receptor by Mena, E E, Gullak, M F, Pagnozzi, M J, Richter, K E, Rivier, J, Cruz, L J, Olivera, B M

“…Conantokin-G is a 17 amino acid peptide isolated from the venom of the fish-eating snail Conus geographus which produces hyperactivity when injected into the…”
Get more information

Characterization of L-glutamate binding sites in rat spinal cord synaptic membranes: evidence for multiple chloride ion-dependent sites by Mena, E E, Pagnozzi, M J, Gullak, M F

“…The effects of various ions on L-glutamate (L-Glu) binding sites (Na+-dependent, Cl(-)-dependent, and Cl(-)-independent) in synaptic plasma membranes (SPM)…”
Get more information