Search Results - "Pagliai, Francesca"

Medicinal Chemistry of Combretastatin A4:  Present and Future Directions by Tron, Gian Cesare, Pirali, Tracey, Sorba, Giovanni, Pagliai, Francesca, Busacca, Sara, Genazzani, Armando A

Get full text

Peripheral blood progenitor uncontrolled-rate freezing: a single pediatric center experience by Iannalfi, Alberto, Bambi, Franco, Tintori, Veronica, Lacitignola, Laura, Bernini, Gabriella, Mariani, Maria Pia, Sanvito, Maria Chiara, Pagliai, Francesca, Brandigi, Francesco, Muscarella, Elisa, Tapinassi, Francesca, Faulkner, Lawrence

“…BACKGROUND: Controlled‐rate freezing (CRF) followed by storage in liquid nitrogen is employed by most centers as the standard procedure for peripheral blood…”
Get full text

Rapid Synthesis of Triazole-Modified Resveratrol Analogues via Click Chemistry by Pagliai, Francesca, Pirali, Tracey, Del Grosso, Erika, Di Brisco, Riccardo, Tron, Gian Cesare, Sorba, Giovanni, Genazzani, Armando A

“…Resveratrol is a phytoalexin able to display an array of biological activities. We decided to replace the double bond with a triazole ring using the…”
Get full text

Rescue treatment with terlipressin in different scenarios of refractory hypotension in newborns and infants by Filippi, Luca, Gozzini, Elena, Daniotti, Marta, Pagliai, Francesca, Catarzi, Serena, Fiorini, Patrizio

“…Terlipressin has been successfully used as rescue treatment in hypotensive adults and children with septic shock, but only exceptionally in neonates. The aim…”
Get full text

Synthesis and Cytotoxic Evaluation of Combretafurazans by Tron, Gian Cesare, Pagliai, Francesca, Del Grosso, Erika, Genazzani, Armando A, Sorba, Giovanni

“…Combretastatin A-4 is an antitumoral and antitubulin agent that is active only in its cis configuration. In the present manuscript, we have synthesized…”
Get full text

Replacement of the lactone moiety on podophyllotoxin and steganacin analogues with a 1,5-disubstituted 1,2,3-triazole via ruthenium-catalyzed click chemistry by Imperio, Daniela, Pirali, Tracey, Galli, Ubaldina, Pagliai, Francesca, Cafici, Laura, Canonico, Pier Luigi, Sorba, Giovanni, Genazzani, Armando A., Tron, Gian Cesare

“…Steganacin and podophyllotoxin are two naturally occurring lignans first isolated from plant sources, which share the capability to disrupt tubulin assembly…”
Get full text

Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life by Saccardi, Riccardo, Mancardi, Gian Luigi, Solari, Alessandra, Bosi, Alberto, Bruzzi, Paolo, Di Bartolomeo, Paolo, Donelli, Amedea, Filippi, Massimo, Guerrasio, Angelo, Gualandi, Francesca, La Nasa, Giorgio, Murialdo, Alessandra, Pagliai, Francesca, Papineschi, Federico, Scappini, Barbara, Marmont, Alberto M.

“…Hematopoietic stem cell transplantation (HSCT) has been proposed for the treatment of severe multiple sclerosis (MS). In a phase 2 multicenter study we…”
Get full text

Synthesis and Cytotoxic Evaluation of Combretafurans, Potential Scaffolds for Dual-Action Antitumoral Agents by Pirali, Tracey, Busacca, Sara, Beltrami, Lorena, Imovilli, Daniela, Pagliai, Francesca, Miglio, Gianluca, Massarotti, Alberto, Verotta, Luisella, Tron, Gian Cesare, Sorba, Giovanni, Genazzani, Armando A

“…We have synthesized rigid analogues of combretastatin bearing a furan ring in place of the olefinic bridge. These compounds are cytotoxic at nanomolar…”
Get full text

Synthesis and biological activity of mustard derivatives of combretastatins by Coggiola, Beatrice, Pagliai, Francesca, Allegrone, Gianna, Genazzani, Armando A., Tron, Gian Cesare

“…[Display omitted] A series of chimeric compounds bearing the combretastatin and the nitrogen mustard cores were synthesized. All the compounds were cytotoxic…”
Get full text

Purified T Depleted Peripheral Blood and Bone Marrow Cd34 Transplantation from Haploidentical Mother to Child with Thalassemia by Sodani, Pietro, Erer, Buket, Gaziev, Javid, Polchi, Paola, Roveda, Andrea, Spitaleri, Luca, Pagliai, Francesca, Paciaroni, Katia, Adorno, Gaspare, Lanti, Alessandro, Isacchi, Giancarlo, Zinno, Francesco, Lucarelli, Guido

“…Approximately 60% of thalassemic patients can not apply to “gene therapy today” which the insertion of one allogenic HLA identical stem cell into the empty…”
Get full text

PET Scan Evaluation of Thymic Mass After Autologous Peripheral Blood Stem-cell Transplantation in an Adult with Non-Hodgkin's Lymphoma by Pagliai, Francesca, Rigacci, Luigi, Briganti, Vittorio, Dini, Catia, Castagnoli, Antonio, Vaggelli, Luca, Bosi, Alberto

“…We report the case of a 31-year-old man with anaplastic large-cell lymphoma successfully treated with chemotherapy who showed mediastinal widening 5 months…”
Get full text

Triazole-Modified Histone Deacetylase Inhibitors As a Rapid Route to Drug Discovery by Pirali, Tracey, Pagliai, Francesca, Mercurio, Ciro, Boggio, Roberto, Canonico, Pier Luigi, Sorba, Giovanni, Tron, Gian Cesare, Genazzani, Armando A

Get full text