Search Results - "Paggiarino, Dario A"

Dose-ranging evaluation of intravitreal siRNA PF-04523655 for diabetic macular edema (the DEGAS study) by Nguyen, Quan Dong, Schachar, Ronald A, Nduaka, Chudy I, Sperling, Marvin, Basile, Anthony S, Klamerus, Karen J, Chi-Burris, Katherine, Yan, Eric, Paggiarino, Dario A, Rosenblatt, Irit, Aitchison, Roger, Erlich, Shai S

“…To evaluate the safety and efficacy of three doses of PF-04523655, a 19-nucleotide methylated double stranded siRNA targeting the RTP801 gene, for the…”
Get full text

Evaluation of the siRNA PF-04523655 versus Ranibizumab for the Treatment of Neovascular Age-related Macular Degeneration (MONET Study) by Nguyen, Quan Dong, MD, MSc, Schachar, Ronald A., MD, PhD, Nduaka, Chudy I., DVM, PhD, Sperling, Marvin, MD, Klamerus, Karen J., PharmD, Chi-Burris, Katherine, MPH, Yan, Eric, PhD, Paggiarino, Dario A., MD, Rosenblatt, Irit, MD, Aitchison, Roger, MS, Erlich, Shai S., PhD

“…Objective To evaluate the efficacy of different dosing paradigms of PF-04523655 (PF) versus ranibizumab (comparator) in subjects with neovascular age-related…”
Get full text

Effect of an Injectable Fluocinolone Acetonide Insert on Recurrence Rates in Chronic Noninfectious Uveitis Affecting the Posterior Segment: Twelve-Month Results by Jaffe, Glenn J, Foster, C Stephen, Pavesio, Carlos E, Paggiarino, Dario A, Riedel, Gerard E

“…To assess the safety and efficacy of an intravitreal fluocinolone acetonide (FA) insert to manage inflammation associated with chronic noninfectious posterior…”
Get full text

A phase 2 study of the sphingosine‐1‐phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma by Pal, Sumanta K., Drabkin, Harry A., Reeves, James A., Hainsworth, John D., Hazel, Susan E., Paggiarino, Dario A., Wojciak, Jon, Woodnutt, Gary, Bhatt, Rupal S.

“…BACKGROUND Upregulation of sphingosine‐1‐phosphate (S1P) may mediate resistance to vascular endothelial growth factor (VEGF)‐directed therapies and inhibit…”
Get full text

Phase I DAVIO Trial: EYP-1901 Bioerodible, Sustained-Delivery Vorolanib Insert in Patients With Wet Age-Related Macular Degeneration by Patel, Sunil, Storey, Philip P., Barakat, Mark R., Hershberger, Vrinda, Bridges, William Z., Eichenbaum, David A., Lally, David R., Boyer, David S., Bakri, Sophie J., Roy, Monica, Paggiarino, Dario A.

“…To evaluate safety and tolerability of EYP-1901, an intravitreal insert containing vorolanib, a pan–VEGF receptor inhibitor packaged in a bioerodible delivery…”
Get full text

Effect of an Injectable Fluocinolone Acetonide Insert on Recurrence Rates in Chronic Noninfectious Uveitis Affecting the Posterior Segment by Jaffe, Glenn J., Foster, C. Stephen, Pavesio, Carlos E., Paggiarino, Dario A., Riedel, Gerard E.

“…To assess the safety and efficacy of an intravitreal fluocinolone acetonide (FA) insert to manage inflammation associated with chronic noninfectious posterior…”
Get full text

Benzydamine HCl for prophylaxis of radiation-induced oral mucositis: results from a multicenter, randomized, double-blind, placebo-controlled clinical trial by Epstein, J B, Silverman, Jr, S, Paggiarino, D A, Crockett, S, Schubert, M M, Senzer, N N, Lockhart, P B, Gallagher, M J, Peterson, D E, Leveque, F G

“…Benzydamine was evaluated in patients with head and neck carcinoma for treatment of radiation-induced oral mucositis, a frequent complication of radiation…”
Get full text

Benzydamine HCl for prophylaxis of radiation‐induced oral mucositis by Epstein, Joel B., Silverman, Sol, Paggiarino, Dario A., Crockett, Steve, Schubert, Mark M., Senzer, Neil N., Lockhart, Peter B., Gallagher, Michael J., Peterson, Douglas E., Leveque, Francis G.

“…BACKGROUND Benzydamine was evaluated in patients with head and neck carcinoma for treatment of radiation‐induced oral mucositis, a frequent complication of…”
Get full text

875 benzydamine HCI for prophylaxis of radiation-induced oral mucositis: Results from a multicenter, randomized, double-blind, placebo-controlled clinical trial by EPSTEIN, Joel B, SILVERMAN, Sol JR, PAGGIARINO, Dario A, CROCKETT, Steve, SCHUBERT, Mark M, SENZER, Neil N, LOCKHART, Peter B, GALLAGHER, Michael J, PETERSON, Douglas E, LEVEQUE, Francis G

Get full text

A prospective randomized comparison of radiation therapy plus lonidamine versus radiation therapy plus placebo as initial treatment of clinically localized but nonresectable nonsmall cell lung cancer by Scarantino, C W, McCunniff, A J, Evans, G, Young, C W, Paggiarino, D A

“…By means of a multicenter, prospective randomized, placebo-controlled study, to assess the impact of adding the radiation-enhancing agent lonidamine to…”
Get more information

Dose-response study of dapiprazole HCl in the reversal of mydriasis induced by 2.5% phenylephrine by Hogan, T S, McDaniel, D D, Bartlett, J D, Hart, K K, Paggiarino, D A

“…Dapiprazole HCL is currently available in the United States for reversal of diagnostic mydriasis. The recommended dosage for this indication is 2 drops…”
Get more information

Lonidamine in head and neck cancer: an overview by Scarantino, C W, Newton, R E, Paggiarino, D A, DeGregorio, M

“…Lonidamine (LNM) has been employed in the treatment of advanced head and neck cancer (H & N) primarily with radiotherapy. It has been proposed that LNM…”
Get more information