Search Results - "Pageon, Laura"

hnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies by Gallardo, Miguel, Lee, Hun Ju, Zhang, Xiaorui, Bueso-Ramos, Carlos, Pageon, Laura R., McArthur, Mark, Multani, Asha, Nazha, Aziz, Manshouri, Taghi, Parker-Thornburg, Jan, Rapado, Inmaculada, Quintas-Cardama, Alfonso, Kornblau, Steven M., Martinez-Lopez, Joaquin, Post, Sean M.

“…hnRNP K regulates cellular programs, and changes in its expression and mutational status have been implicated in neoplastic malignancies. To directly examine…”
Get full text

Theranostic probe for simultaneous in vivo photoacoustic imaging and confined photothermolysis by pulsed laser at 1064 nm in 4T1 breast cancer model by Zhou, Min, Ku, Geng, Pageon, Laura, Li, Chun

“…Here, we report that polyethylene glycol (PEG)-coated copper(II) sulfide nanoparticles (PEG-CuS NPs) with their peak absorption tuned to 1064 nm could be used…”
Get more information

Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas by Gallardo, Miguel, Malaney, Prerna, Aitken, Marisa J L, Zhang, Xiaorui, Link, Todd M, Shah, Vrutant, Alybayev, Sanzhar, Wu, Meng-Han, Pageon, Laura R, Ma, Huaxian, Jacamo, Rodrigo, Yu, Li, Xu-Monette, Zijun Y, Steinman, Haley, Lee, Hun Ju, Sarbassov, Dos, Rapado, Inmaculada, Barton, Michelle C, Martinez-Lopez, Joaquin, Bueso-Ramos, Carlos, Young, Ken H, Post, Sean M

“…Abstract Background Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is an RNA-binding protein that is aberrantly expressed in cancers. We and others have…”
Get full text

Pathology in Practice by Sigmund, Alex B, Fasina, Olufemi, Helgert, Nathan D, Miller, Debra L, Ward, Daniel A, Hendrix, Diane V H

“…In collaboration with the American College of Veterinary Pathologists…”
Get full text

Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates by Laffan, Susan B, Thomson, Andrew S, Mai, Shing, Fishman, Cindy, Kambara, Takahito, Nistala, Kiran, Raymond, James T, Chen, Shugui, Ramani, Thulasi, Pageon, Laura, Polsky, Rodd, Watkins, Mark, Ottolangui, Gemma, White, John R, Maier, Curtis, Herdman, Michael, Bouma, Gerben

“…Despite the potential for the chemokine class as therapeutic targets in immune mediated disease, success has been limited. Many chemokines can bind to multiple…”
Get full text

Tissue-specific and age-dependent effects of global Mdm2 loss by Zhang, Yun, Xiong, Shunbin, Li, Qin, Hu, Sophia, Tashakori, Mehrnoosh, Van Pelt, Carolyn, You, Mingjian James, Pageon, Laura, Lozano, Guillermina

“…Mdm2, an E3 ubiquitin ligase, negatively regulates the tumour suppressor p53. In this study we utilized a conditional Mdm2 allele, Mdm2FM, and a CAG–CreER…”
Get full text

Pathology in Practice by Kendricks, April L, Pageon, Laura R, Craig, Suzanne L, Wen, Yunfei, Sood, Anil K, Lockworth, Cynthia R

Get full text

Pilot in vivo study of an absorbable polydioxanone vena cava filter by Eggers, Mitchell D., PhD, MBA, McArthur, Mark J., DVM, DACVP, Figueira, Tomas A., MD, Abdelsalam, Mohamed E., MD, Dixon, Katherine P., RT, ARRT, Pageon, Laura R., DVM, Wallace, Michael J., MD, Huang, Steven Y., MD

“…Objective The objectives of this study were to evaluate tensile strength retention of polydioxanone as a function of time in a swine venous system and to…”
Get full text

Identification of a Novel Regulator of AML by Gallardo, Miguel, PhD, Lee, Hun Ju, MD, Zhang, Xiaorui, Pageon, Laura, DVMS, Multani, Asha, PhD, Bueso-Ramos, Carlos, MD, PhD, Kornblau, Steven, MD, Post, Sean M., PhD

Get full text

Pathology in Practice by Behrana Jensen, Vanessa, Humphreys, Alan F, Pageon, Laura R, Samuels, Dawn L, Trimble, Amanda L, Mendoza, Alberto, Whitley, Elizabeth M

“…In collaboration with the American College of Veterinary Pathologists…”
Get full text

The serine protease inhibitor elafin maintains normal growth control by opposing the mitogenic effects of neutrophil elastase by Caruso, J A, Akli, S, Pageon, L, Hunt, K K, Keyomarsi, K

“…The serine protease inhibitor, elafin, is a critical component of the epithelial barrier against neutrophil elastase (NE). Elafin is downregulated in the…”
Get full text

hnRNP K: A Regulator of Global Transcription and Translation That Drives Lymphomagenesis by Malaney, Prerna, Gallardo, Miguel, Hornbaker, Marisa J, Zhang, Xiaorui, Link, Todd, Shah, Vrutant, Alybayev, Sanzhar, Wu, Meng-Han, Pageon, Laura R, Ma, Huaxian, Jacamo, Rodrigo, Yu, Li, Xu-Monette, Zijun Yidan, Steinman, Haley, Lee, Hun Ju, Sarbassov, Dos, Rapado, Inmaculada, Barton, Michelle, Martinez-Lopez, Joaquin, Bueso-Ramos, Carlos E., Young, Ken H., Post, Sean M

“…hnRNP K is an RNA binding protein that controls a multitude of cellular processes and is aberrantly expressed in cancers. We have previously shown that hnRNP K…”
Get full text

hnRNP K: A Tumor Suppressor or Oncogene? by Gallardo, Miguel, Lee, Hun Ju, Bueso-Ramos, Carlos E., Zhang, Xiaorui, Pageon, Laura R., Multani, Asha, Rapado, Inmaculada, Quintás-Cardama, Alfonso, Kornblau, Steven M., Martinez-Lopez, Joaquin, Post, Sean M.

“…Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is an RNA and DNA binding protein that regulates critical pathways controlling differentiation and…”
Get full text

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression by Gallardo, Miguel, Lee, Hun Ju, Zhang, Xiaorui, Pageon, Laura R., Multani, Asha, Reschke, Markus, Clohessy, John G, Quintás-Cardama, Alfonso, Andreeff, Michael, Kornblau, Steven M., Pandolfi, Pier Paolo, Post, Sean M.

“…NPM1 mutations are one of the most common alterations observed in acute myeloid leukemia (AML). When coupled with wild type FLT3 status in cytogenetically…”
Get full text

hnRNP K: A Novel Regulator of Hematopoiesis and A Potential Predictive Biomarker In Acute Myeloid Leukemia by Gallardo, Miguel, Lee, Hun Ju, Zhang, Xiaorui, Nazha, Aziz, Pageon, Laura R., Kornblau, Steven M., Quintás-Cardama, Alfonso, Post, Sean M.

“…In acute myeloid leukemia (AML), numerous genetic and epigenetic changes have been identified that result in loss of differentiation, apoptosis, and cell cycle…”
Get full text

hnRNP K Is a Novel Haploinsufficient Tumor Suppressor at the 9q21.32 Locus That Defines a Subset of AML by Gallardo, Miguel, Lee, Hun Ju, Zhang, Xiaorui, Bueso-Ramos, Carlos E., Pageon, Laura, McArthur, Mark, Multani, Asha, Nazha, Aziz, Manshouri, Taghi, Parker-Thornburg, Jan, Hu, Peter, Qi, Yuan, Su, Xiaoping, Rapado, Inmaculada, Quintás-Cardama, Alfonso, Kornblau, Steven M., Martinez-López, Joaquin, Post, Sean M.

“…Deletion of the 9q21.32 locus is observed in some patients with AML, suggesting an undescribed tumor suppressor resides in this region. HNRNPK is an attractive…”
Get full text