Search Results - "Pagella, P G"

The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents by Dawson, G R, Bentley, G, Draper, F, Rycroft, W, Iversen, S D, Pagella, P G

“…We assessed the effects of heptyl physostigmine, a new cholinesterase inhibitor, in a mouse tail-flick (TF) test, a mouse and rat passive avoidance test, a rat…”
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6-Aminoquinolones: A New Class of Quinolone Antibacterials? by Cecchetti, Violetta, Clementi, Sergio, Cruciani, Gabriele, Fravolini, Arnaldo, Pagella, Pier Giuseppe, Savino, Angela, Tabarrini, Oriana

“…A series of quinolone- and 1,8-naphthyridone-3-carboxylic acids, designed by previous QSAR studies and characterized by an amino group at the C-6 position…”
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Reversal of cognitive impairment by heptyl physostigmine, a long-lasting cholinesterase inhibitor, in primates by Rupniak, N M, Tye, S J, Brazell, C, Heald, A, Iversen, S D, Pagella, P G

“…Cholinergic replacement therapy for Alzheimer's disease using existing cholinesterase inhibitors is compromised by short duration, meagre benefits restricted…”
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A long-lasting cholinesterase inhibitor affecting neural and behavioral processes by Brufani, M, Castellano, C, Marta, M, Oliverio, A, Pagella, P G, Pavone, F, Pomponi, M, Rugarli, P L

“…A series of analogues of physostigmine were prepared with the aim of investigating their inhibitory effects on acetylcholinesterase in the treatment of…”
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Effects of MF-268, a new cholinesterase inhibitor, on acetylcholine and biogenic amines in rat cortex by Zhu, X.-D., Cuadra, G., Brufani, M., Maggi, T., Pagella, P. G., Williams, E., Giacobini, E.

“…MF‐268 bitartrate [(3a S, 8a R)‐1,2,3,3a,8,8a‐hexahydro‐1,3a,8‐trimethylpyrrolo[2,3‐b]indol‐5‐ol[8‐(cis2, 6‐dimethyl‐morpholin‐4‐yl)octyl]‐carbamate…”
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New analogs of physostigmine: alternative drugs for Alzheimer's disease? by Marta, M, Castellano, C, Oliverio, A, Pavone, F, Pagella, P G, Brufani, M, Pomponi, M

“…The synthesis of a series of physostigmine analogs, in which the methylcarbamyl group has been substituted with monoalkylcarbamyl, dimethyl- and…”
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Antithrombotic properties of dermatan sulphate in a rat venous thrombosis model by Maggi, A, Abbadini, M, Pagella, P G, Borowska, A, Pangrazzi, J, Donati, M B

“…It has been suggested that glycosaminoglycans (GAG) such as heparan sulphate (HS), dermatan sulphate (DS), chondroitin-4-sulphate and chondroitin-6-sulphate…”
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Synthesis of phenothiazine derivatives as potential inhibitors of phospholipase C by Brufani, M, Cesta, M C, Filocamo, L, Lappa, S, Marta, M, Pomponi, M, Meroni, C, Pagella, P G

“…In order to study the structure-activity relationships of phenothiazine derivatives inhibiting phosphatidylinositol-specific phospholipase C (PI-PLC), the…”
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In vitro activity of MF 5137, a new potent 6-aminoquinolone by Wise, R, Pagella, P G, Cecchetti, V, Fravolini, A, Tabarrini, O

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Drug modulation of superoxide anion production from human neutrophils by Fantozzi, R, Brunelleschi, S, Cremonesi, P, Pagella, P G, Ciani, D, Sportoletti, G C

“…The effects of drugs on the production of superoxide anion from neutrophils stimulated by N-formylmethionyl-leucyl-phenylalanine (FMLP) were examined. Drugs…”
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Pharmacological and toxicological studies on an iron succinyl-protein complex (ITF282) for oral treatment of iron deficiency anemia by Pagella, P G, Bellavite, O, Agozzino, S, Donà, G C

“…ITF282, a soluble iron succinyl-protein complex, orally administered to the rat elevates the concentration of iron in the serum to a greater extent than…”
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Different sensitivity of basilar and saphenous arteries to thromboxane A2-induced contractions. Effect of imidazole 2-hydroxybenzoate (ITF 182) by Pagella, P G, Agozzino, S, Bellavite, O, Donà, G C, Mendola, N

“…Superfused rings of rabbit basilar arteries are more sensitive than those of saphenous arteries to the contractions induced by a prostaglandin endoperoxide…”
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Determination of heptylphysostigmine in plasma by high-performance liquid chromatography with electrochemical detection by Zecca, L, Radice, D, Mosca, A, Pagella, P G

“…Heptylphysostigmine is a new and very promising cholinergic drug for the treatment of Alzheimer disease. A method has been developed for its determination in…”
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Reversible inhibition of thromboxane A2 production by imidazole 2-hydroxybenzoate (ITF 182) in the arachidonic acid injected rat. A comparison with acetylsalicylic acid and indometacin by Pagella, P G, Agozzino, S, Bellavite, O, Donà, G C

“…The behavior of imidazole 2-hydroxybenzoate (ITF 182), acetylsalicylic acid (ASA) and indometacin (INN; in some pharmacopoeias called indomethacin) in…”
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Quinolinecarboxylic acids. 3. Synthesis and antibacterial evaluation of 2-substituted 7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acids related to rufloxacin by Cecchetti, Violetta, Fravolini, Arnaldo, Pagella, Pier Giuseppe, Savino, Angela, Tabarrini, Oriana

“…A series of 2-substituted-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6 -carboxylic acids has been prepared and evaluated for in vitro…”
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Penetration of imidazole 2-hydroxybenzoate (ITF 182) into experimentally inflamed pleural and knee joint exudates by Pagella, P G, Agozzino, S, Bellavite, O, Donà, G C, Galimberti, G, Cremonesi, P

“…The penetration of the two components of imidazole 2-hydroxybenzoate (ITF 182), imidazole and salicylate, into inflamed sites induced by intrapleural injection…”
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Effect of arginine thiazolidinecarboxylate on allyl alcohol hepatotoxicity in the rat by Pagella, P G, Faini, D, Turba, C

“…The effect of arginine thiazolidinecarboxylate on allyl alcohol hepatotoxicity in the rat was studied. Serum glutamic oxalacetic transaminase (SGOT), serum…”
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Synthesis of some carbamates of myo-inositol by Brufani, M, Cesta, M C, Donnarumma, L, Filocamo, L, Gostoli, G, Lappa, S, Ferrari, E, Pagella, P G

“…The syntheses are described of the 1-O-carbamoyl (11), 1-O-carbamoyl-2-O-stearoyl (10), 1-O-(acetylcarbamoyl)-2-O-stearoyl (12), 1-O-(heptylcarbamoyl) (13),…”
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Synthesis and beta-adrenergic blocking activity of oxipropanolamines of 3,4-dihydro-3-oxo-2H(1,4)benzothiazine by Cecchetti, V, Fravolini, A, Fringuelli, R, Schiaffella, F, Mascellani, G, Pagella, P G, Rugarli, P L

“…The synthesis of a series of oxypropanolamines of 3,4-dihydro-3-oxo-2H(1,4)benzothiazine is reported. Some of these compounds proved more potent than…”
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Pharmacological studies of imidazole 2-hydroxybenzoate (ITF 182), an antiinflammatory compound with an action on thromboxane A2 production by Pagella, P G, Bellavite, O, Agozzino, S, Donà, G C, Cremonesi, P, De Santis, F

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