Search Results - "Page, Raymond"

Biomimetic scaffolds for regeneration of volumetric muscle loss in skeletal muscle injuries by Grasman, Jonathan M., Zayas, Michelle J., Page, Raymond L., Pins, George D.

“…[Display omitted] Skeletal muscle injuries typically result from traumatic incidents such as combat injuries where soft-tissue extremity injuries are present…”
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Rapid release of growth factors regenerates force output in volumetric muscle loss injuries by Grasman, Jonathan M, Do, Duc M, Page, Raymond L, Pins, George D

“…Abstract A significant challenge in the design and development of biomaterial scaffolds is to incorporate mechanical and biochemical cues to direct organized…”
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Circulating tumor cell assay to non-invasively evaluate PD-L1 and other therapeutic targets in multiple cancers by Page, Raymond, Patil, Darshana, Akolkar, Dadasaheb, Murthy, Sudha S, Bendale, Kiran, Patil, Revati, Fulmali, Pradeep, Fulmali, Pooja, Adhav, Archana, Puranik, Sneha, Apurwa, Sachin, Datta, Vineet, Bose, Chirantan, Schuster, Stefan, John, Jinumary, Srinivasan, Ajay, Datar, Rajan

“…Biomarker directed selection of targeted anti-neoplastic agents such as immune checkpoint inhibitors, small molecule inhibitors and monoclonal antibodies form…”
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Restoration of skeletal muscle defects with adult human cells delivered on fibrin microthreads by Page, Raymond L, Malcuit, Christopher, Vilner, Lucy, Vojtic, Ina, Shaw, Sharon, Hedblom, Emmett, Hu, Jason, Pins, George D, Rolle, Marsha W, Dominko, Tanja

“…Large-scale musculoskeletal wounds, such as those seen in trauma injuries, present poor functional healing prognoses. In severe trauma, when the native tissue…”
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Improved Treatment Outcomes by Using Patient Specific Drug Combinations in Mammalian Target of Rapamycin Activated Advanced Metastatic Cancers by Crook, Timothy, Patil, Darshana, Gaya, Andrew, Plowman, Nicholas, Limaye, Sewanti, Ranade, Anantbhushan, Bhatt, Amit, Page, Raymond, Akolkar, Dadasaheb

“…Activation of the mTOR signaling pathway is ubiquitous in cancers and a favourable therapeutic target. However, presently approved mTOR inhibitor monotherapies…”
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Crosslinking strategies facilitate tunable structural properties of fibrin microthreads by Grasman, Jonathan M., Page, Raymond L., Dominko, Tanja, Pins, George D.

“…A significant challenge in the design of biomimetic scaffolds is combining morphologic, mechanical, and biochemical cues into a single construct to promote…”
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Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells by Ambady, Sakthikumar, Malcuit, Christopher, Kashpur, Olga, Kole, Denis, Holmes, William F, Hedblom, Emmett, Page, Raymond L, Dominko, Tanja

“…The transcription factor NANOG is essential for maintaining pluripotency in embryonic stem cells. We have previously reported the expression of NANOG in adult…”
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Cloned pigs produced by nuclear transfer from adult somatic cells by Polejaeva, Irina A, Chen, Shu-Hung, Vaught, Todd D, Page, Raymond L, Mullins, June, Ball, Suyapa, Dai, Yifan, Boone, Jeremy, Walker, Shawn, Ayares, David L, Colman, Alan, Campbell, Keith H. S

“…Since the first report of live mammals produced by nuclear transfer from a cultured differentiated cell population in 1995 (ref. 1), successful development has…”
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Maintenance of multipotency in human dermal fibroblasts treated with Xenopus laevis egg extract requires exogenous fibroblast growth factor-2 by Kole, Denis, Ambady, Sakthikumar, Page, Raymond L, Dominko, Tanja

“…Direct reprogramming of a differentiated somatic cell into a developmentally more plastic cell would offer an alternative to applications in regenerative…”
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Gene expression profiling of single bovine embryos uncovers significant effects of in vitro maturation, fertilization and culture by Smith, Sadie L., Everts, Robin E., Sung, Li-Ying, Du, Fuliang, Page, Raymond L., Henderson, Boyd, Rodriguez-Zas, Sandra L., Nedambale, Tshimangadzo L., Renard, Jean-Paul, Lewin, Harris A., Yang, Xiangzhong, Tian, X. Cindy

“…In vitro production (IVP) has been shown to affect embryonic gene expression and often result in large offspring syndrome (LOS) in cattle and sheep. To dissect…”
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Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle by Curchoe, Carol Lynn, Zhang, Shouquan, Yang, Lan, Page, Raymond, Tian, X. Cindy

“…Bos taurus is a good model for embryo biotechnologies such as nuclear transfer. However, animals produced from these technologies often suffer from large calf…”
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Genomic Imprinting of H19 in Naturally Reproduced and Cloned Cattle by Zhang, Shouquan, Kubota, Chikara, Yang, Lan, Zhang, Yuqin, Page, Raymond, O'Neill, Michael, Yang, Xiangzhong, Tian, X Cindy

“…Animals produced from assisted reproductive technologies suffer from developmental abnormalities and early fetal death at a higher frequency than that observed…”
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Designing Biopolymer Microthreads for Tissue Engineering and Regenerative Medicine by O’Brien, Megan P., Carnes, Meagan E., Page, Raymond L., Gaudette, Glenn R., Pins, George D.

“…Native tissue structures possess elaborate extracellular matrix (ECM) architectures that inspire the design of fibrous structures in the field of regenerative…”
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Intracytoplasmic sperm injection in the bovine induces abnormal [Ca2+]i responses and oocyte activation by Malcuit, Christopher, Maserati, Marc, Takahashi, Yoshiyuki, Page, Raymond, Fissore, Rafael A

“…Fertilisation by intracytoplasmic sperm injection (ICSI), a technique that bypasses the membrane fusion of the gametes, has been widely used to produce…”
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Genomic Imprinting of H19 in Naturally Reproduced and Cloned Cattle1 by Zhang, Shouquan, Kubota, Chikara, Yang, Lan, Zhang, Yuqin, Page, Raymond, O'Neill, Michael, Yang, Xiangzhong, Tian, X. Cindy

“…Animals produced from assisted reproductive technologies suffer from developmental abnormalities and early fetal death at a higher frequency than that observed…”
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Spectrum of HER2 alterations in NSCLC: Comparative analysis of tissue and liquid biopsies in lung cancer by Choudhary, R. K., Koppaka, Deepak, Vaid, Ashok K, Kulkarni, Shriniwas Subhash, Bose, Chirantan, Morzaria, Dr Disha, Apurwa, Sachin, Vijayan, Poornima, Bhatt, Amit Dilip, Ranade, Anantbhushan, Page, Raymond, Patil, Darshana, Akolkar, Dadasaheb, Limaye, Sewanti

“…e20602 Background: Non-Small Cell Lung Cancer (NSCLC) exhibits a spectrum of molecular alterations that play a crucial role in understanding its heterogeneity…”
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High-Level Expression of a Heterologous Protein in the Milk of Transgenic Swine Using the cDNA Encoding Human Protein C by Velander, William H., Johnson, John L., Page, Raymond L., Russell, Christopher G., Subramanian, Anuradha, Wilkins, Tracy D., Gwazdauskas, Francis C., Pittius, Christoph, Drohan, William N.

“…Transgenic pigs were generated that produced human protein C in their milk at up to 1 g/liter. The gene construct was a fusion gene consisting of the cDNA for…”
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Hallmark Circulating Tumor-Associated Cell Clusters Signify 230 Times Higher One-Year Cancer Risk by Ranade, Anantbhushan, Bhatt, Amit, Page, Raymond, Limaye, Sewanti, Crook, Timothy, Akolkar, Dadasaheb, Patil, Darshana

“…We have previously shown that circulating ensembles of tumor-associated cells (C-ETACs) are a systemic hallmark of cancer based on analysis of blood samples…”
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Circulating ensembles of tumor‐associated cells: A redoubtable new systemic hallmark of cancer by Akolkar, Dadasaheb, Patil, Darshana, Crook, Timothy, Limaye, Sewanti, Page, Raymond, Datta, Vineet, Patil, Revati, Sims, Cynthe, Ranade, Anantbhushan, Fulmali, Pradeep, Fulmali, Pooja, Srivastava, Navin, Devhare, Pradip, Apurwa, Sachin, Patel, Shoeb, Patil, Sanket, Adhav, Archana, Pawar, Sushant, Ainwale, Akshay, Chougule, Rohit, Apastamb, Madhavi, Srinivasan, Ajay, Datar, Rajan

“…Circulating ensembles of tumor‐associated cells (C‐ETACs) which comprise tumor emboli, immune cells and fibroblasts pose well‐recognized risks of thrombosis…”
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Accurate Screening for Early-Stage Breast Cancer by Detection and Profiling of Circulating Tumor Cells by Crook, Timothy, Leonard, Robert, Mokbel, Kefah, Thompson, Alastair, Michell, Michael, Page, Raymond, Vaid, Ashok, Mehrotra, Ravi, Ranade, Anantbhushan, Limaye, Sewanti, Patil, Darshana, Akolkar, Dadasaheb, Datta, Vineet, Fulmali, Pradip, Apurwa, Sachin, Schuster, Stefan, Srinivasan, Ajay, Datar, Rajan

“…Background: The early detection of breast cancer (BrC) is associated with improved survival. We describe a blood-based breast cancer detection test based on…”
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