Search Results - "Page, M. G. P."

Extended-spectrum β-lactamases: structure and kinetic mechanism by Page, M.G.P.

“…Recent years have seen an explosion in the numbers of extented spectrum class A β-lactamases (ESBLs). The steady-state kinetic parameters for hydrolysis of…”
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The kinetics of non-stoichiometric bursts of β-lactam hydrolysis catalysed by class C β-lactamases by PAGE, M. G. P

“…Class C beta-lactamases from Pseudomonas aeruginosa and several species of the Enterobacteriaceae have been observed to undergo a rapid burst in hydrolysis of…”
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In vitro activity of the siderophore monosulfactam BAL30072 against meropenem-non-susceptible Acinetobacter baumannii by HIGGINS, Paul G, STEFANIK, Danuta, PAGE, Malcolm G. P, HACKEL, Meredith, SEIFERT, Harald

“…The activity of BAL30072 was compared with that of anti-Acinetobacter reference drugs against meropenem-non-susceptible Acinetobacter baumannii isolates…”
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Combined effects of the siderophore monosulfactam BAL30072 and carbapenems on multidrug-resistant Gram-negative bacilli by Hofer, Beatrice, Dantier, Clothilde, Gebhardt, Klaus, Desarbre, Eric, Schmitt-Hoffmann, Anne, Page, Malcolm G P

“…Carbapenem resistance in Gram-negative bacteria, mediated by restricted net influx and carbapenem-hydrolysing β-lactamases, is a growing problem. The…”
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In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii by RUSSO, Thomas A, PAGE, Malcolm G. P, BEANAN, Janet M, OLSON, Ruth, HUJER, Andrea M, HUJER, Kristine M, JACOBS, Michael, BAJAKSOUZIAN, Saralee, ENDIMIANI, Andrea, BONOMO, Robert A

“…New antibiotics that are active against multidrug-resistant (MDR) Acinetobacter baumannii are urgently needed. BAL30072, a siderophore monosulfactam antibiotic…”
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A kinetic analysis of the inhibition of FOX-4  -lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic  -lactams and carbapenems by Papp-Wallace, K. M., Mallo, S., Bethel, C. R., Taracila, M. A., Hujer, A. M., Fernandez, A., Gatta, J. A., Smith, K. M., Xu, Y., Page, M. G. P., Desarbre, E., Bou, G., Bonomo, R. A.

“…Class C β-lactamases are prevalent among Enterobacteriaceae; however, these enzymes are resistant to inactivation by commercially available β-lactamase…”
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Hydroxamic Acid Derivatives as Potent Peptide Deformylase Inhibitors and Antibacterial Agents by Apfel, Christian, Banner, David W, Bur, Daniel, Dietz, Michel, Hirata, Takahiro, Hubschwerlen, Christian, Locher, Hans, Page, Malcolm G. P, Pirson, Wolfgang, Rossé, Gérard, Specklin, Jean-Luc

“…Low-molecular-weight β-sulfonyl- and β-sulfinylhydroxamic acid derivatives have been synthesized and found to be potent inhibitors of Escherichia coli peptide…”
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Restriction site-free insertion of PCR products directionally into vectors by Chen, G J, Qiu, N, Karrer, C, Caspers, P, Page, M G

“…A restriction site-free cloning method has been developed for inserting a PCR product into a vector flexibly and precisely at any desired location with high…”
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Structure-Based Design of β-Lactamase Inhibitors. 1. Synthesis and Evaluation of Bridged Monobactams by Heinze-Krauss, Ingrid, Angehrn, Peter, Charnas, Robert L, Gubernator, Klaus, Gutknecht, Eva-Maria, Hubschwerlen, Christian, Kania, Malgosia, Oefner, Christian, Page, Malcolm G. P, Sogabe, Satoshi, Specklin, Jean-Luc, Winkler, Fritz

“…Bridged monobactams are novel, potent, mechanism-based inhibitors of class C β-lactamases, designed using X-ray crystal structures of the enzymes. They…”
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Design, Synthesis, and Evaluation of 2β-Alkenyl Penam Sulfone Acids as Inhibitors of β-Lactamases by Richter, Hans G. F, Angehrn, Peter, Hubschwerlen, Christian, Kania, Malgosia, Page, Malcolm G. P, Specklin, Jean-Luc, Winkler, Fritz K

“…A general method for synthesis of 2β-alkenyl penam sulfones has been developed. The new compounds inhibited most of the common types of β-lactamase. The level…”
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Structure-Based Design of β-Lactamase Inhibitors. 2. Synthesis and Evaluation of Bridged Sulfactams and Oxamazins by Hubschwerlen, Christian, Angehrn, Peter, Gubernator, Klaus, Page, Malcolm G. P, Specklin, Jean-Luc

“…A series of bridged monocyclic β-lactams activated by various groups on the β-lactam nitrogen (X = OCH2CO2H, OSO3H) has been synthesized and evaluated. Among…”
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Cloning and characterization of a novel, plasmid-encoded trimethoprim-resistant dihydrofolate reductase from Staphylococcus haemolyticus MUR313 by DALE, G. E, LANGEN, H, PAGE, M. G. P, THEN, R. L, STÜBER, D

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Synthesis and Structure−Activity Relationship of (Lactamylvinyl)cephalosporins Exhibiting Activity against Staphylococci, Pneumococci, and Enterococci by Heinze-Krauss, Ingrid, Angehrn, Peter, Guerry, Philippe, Hebeisen, Paul, Hubschwerlen, Christian, Kompis, Ivan, Page, Malcolm G. P, Richter, Hans G. F, Runtz, Valérie, Stalder, Henri, Weiss, Urs, Wei, Chung-Chen

“…The synthesis and structure−activity relationships of a new class of vinylcephalosporins substituted with a lactamyl residue (1) are described. These compounds…”
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Topography of lactose permease from Escherichia coli by Page, M G, Rosenbusch, J P

“…The topography of lactose permease, in native membrane vesicles and after reconstitution of the purified protein into proteoliposomes, has been investigated by…”
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Cloning, over-expression and the catalytic properties of the EcoP15 modification methylase from Escherichia coli by Rao, D N, Page, M G, Bickle, T A

“…The EcoP15 modification methylase gene from the p15B plasmid of Escherichia coli 15T-has been cloned and expressed at high levels in a plasmid vector system…”
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The reaction of cephalosporins with penicillin-binding protein 1b gamma from Escherichia coli by Page, M G

“…The kinetics of the reaction of purified penicillin-binding protein 1b gamma from Escherichia coli with cephalosporins suggest that the enzyme exists in two…”
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The effects of pH on proton sugar symport activity of the lactose permease purified from Escherichia coli by Page, M G, Rosenbusch, J P, Yamato, I

“…The lactose permease, which catalyzes galactoside-proton symport into Escherichia coli, has been purified and reconstituted in active form into artificial…”
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Crystallization and preliminary X-ray characterization of maltoporin from Escherichia coli by Stauffer, K A, Page, M G, Hardmeyer, A, Keller, T A, Pauptit, R A

“…Crystals of maltoporin (the bacteriophage lambda receptor of Escherichia coli) that diffract X-rays to 3 A resolution can be grown reproducibly. Maltoporin is…”
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The role of protons in the mechanism of galactoside transport via the lactose permease of Escherichia coli by Page, M G

“…The kinetic mechanism of lactose transport across the cytoplasmic membrane has been investigated and the results related to standard models for the lactose-H+…”
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Topographic labelling of pore-forming proteins from the outer membrane of Escherichia coli by Page, M G, Rosenbusch, J P

“…The topography of three pore-forming proteins from the outer membrane of Escherichia coli has been explored by using two labelling techniques. Firstly, the…”
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