Search Results - "Pagano, Maurice"

Toward the First Class of Suicide Inhibitors of Kallikreins Involved in Skin Diseases by Tan, Xiao, Soualmia, Feryel, Furio, Laetitia, Renard, Jean-François, Kempen, Isabelle, Qin, Lixian, Pagano, Maurice, Pirotte, Bernard, El Amri, Chahrazade, Hovnanian, Alain, Reboud-Ravaux, Michèle

“…The inhibition of kallikreins 5 and 7, and possibly kallikrein 14 and matriptase, (that initiates the kallikrein proteolytic cascade) constitutes an innovative…”
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Cryptic activities of fibronectin fragments, particularly cryptic proteases by Pagano, Maurice, Reboud-Ravaux, Michele

“…Fibronectin (FN) is a modular glycoprotein encoded by a single gene. A soluble form of this protein is found in the plasma of several animals. Alternative…”
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Zinc Induces Structural Reorganization of Gelatin Binding Domain from Human Fibronectin and Affects Collagen Binding by Graille, Marc, Pagano, Maurice, Rose, Thierry, Ravaux, Michèle Reboud, van Tilbeurgh, Herman

“…Fibronectin is a modular extracellular matrix protein involved in cell adhesion, cell motility, wound healing, and maintenance of cell morphology. It is…”
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Linear TMC-95-Based Proteasome Inhibitors by Basse, Nicolas, Piguel, Sandrine, Papapostolou, David, Ferrier-Berthelot, Alexandra, Richy, Nicolas, Pagano, Maurice, Sarthou, Pierre, Sobczak-Thépot, Joëlle, Reboud-Ravaux, Michèle, Vidal, Joëlle

“…We have designed and evaluated 45 linear analogues of the natural constrained cyclopeptide TMC-95A. These synthetically less demanding molecules are based on…”
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Application of electrophoresis and related methods, such as western blotting and zymography to the study of some proteins and enzymes by Pagano, Maurice

“…Electrophoresis and related methods are currently used by laboratories working on proteins. This review focuses on four different applications of acrylamide…”
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Liberation of an N-terminal proline-rich peptide from the cryptic proteinase of fibronectin by auto-proteolysis by Pagano, Maurice, Clodic, Gilles, Bolbach, Gérard, Michiel, Magalie, Haddag, Saliha, Reboud-Ravaux, Michèle

“…Fibronectin (Fn) is a modular glycoprotein present in both the extra-cellular matrix and blood plasma. It has a cryptic zinc-metalloproteinase activity…”
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Development of lipopeptides for inhibiting 20S proteasomes by Basse, Nicolas, Papapostolou, David, Pagano, Maurice, Reboud-Ravaux, Michèle, Bernard, Elise, Felten, Anne-Sophie, Vanderesse, Régis

“…Proteasomes are responsible for the cytoplasmic turnover of the vast majority of proteins including regulatory proteins. We have synthesized lipopeptides a new…”
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Vascular smooth muscle cells efficiently activate a new proteinase cascade involving plasminogen and fibronectin by Houard, Xavier, Monnot, Catherine, Dive, Vincent, Corvol, Pierre, Pagano, Maurice

“…The plasminogen/plasmin system is involved in vascular wall remodeling after injury, through extracellular matrix (ECM) degradation and proteinase activation…”
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Linear TMC-95-based proteasome inhibitors by Basse, Nicolas, Piguel, Sandrine, Papapostolou, David, Ferrier-Berthelot, Alexandra, Richy, Nicolas, Pagano, Maurice, Sarthou, Jacques, Sobczak-Thépot, Joëlle, Reboud-Ravaux, Michèle, Vidal, Joëlle

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Binding of the Cysteine Proteinases Papain and Cathepsin B-like to Coated Laminin: Use of Synthetic Peptides from Laminin and from the Laminin Binding Region of the β1Integrin Subunit to Characterize the Binding Site by Dalet-Fumeron, Véronique, Boudjennah, Laziz, Pagano, Maurice

“…Cysteine proteinases of the papain superfamily, i.e., papain and cathepsin B-like proteinase, were found to be able to bind to laminin-coated wells. When…”
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Synthesis of Peptidyl Ene Diones: Selective Inactivators of the Cysteine Proteinases by Darkins, Paul, Gilmore, Brendan F., Hawthorne, Susan J., Healy, Adrienne, Moncrieff, Hazel, McCarthy, Noreen, Anthony McKervey, M., Brömme, Dieter, Pagano, Maurice, Walker, Brian

“…A series of synthetic peptides in which the C‐terminal carboxyl grouping (‐CO2H) of each has been chemically converted into a variety of ene dione derivatives…”
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In vitro activation of pro-cathepsin B by three serine proteinases: leucocyte elastase, cathepsin G, and the urokinase-type plasminogen activator by Dalet-Fumeron, Veronique, Guinec, Nathalie, Pagano, Maurice

“…In vitro activation of pro-cathepsin B purified from ascitic fluid of ovarian carcinomas by serine proteinases was studied. Both elastase and cathepsin G from…”
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Competition between Plasminogen and Procathepsin B as a Probe to Demonstrate thein VitroActivation of Procathepsin B by the Tissue Plasminogen Activator by Dalet-Fumeron, Véronique, Boudjennah, Laziz, Pagano, Maurice

“…The tissue plasminogen activator (tPA) was found to activatein vitrothe procathepsin B purified from malignant ascitic fluids. This activation was time and…”
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Competition between plasminogen and procathepsin B as a probe to demonstrate the in vitro activation of procathepsin B by the tissue plasminogen activator by Dalet-Fumeron, V, Boudjennah, L, Pagano, M

“…The tissue plasminogen activator (tPA) was found to activate in vitro the procathepsin B purified from malignant ascitic fluids. This activation was time and…”
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Partial Characterization of a Novel Cathepsin L-like Protease from Fasciola hepatica by Hawthorne, Susan J., Pagano, Maurice, Halton, David W., Walker, Brian

“…A 30-kDa protease, purified previously from Fasciola hepatica, was sequenced and the first 15 N-terminal residues were found to be 100% homologous to a region…”
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Comparison of cysteine-proteinases inhibitory properties of human high-molecular-weight-kininogen (HMrK) purified from plasma and serum by Pagano, M

“…We have purified both plasma and serum High Molecular Weight Kininogens (HMrK) and studied their inhibitory properties against members of the cysteine…”
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"In vitro" study of basement membrane degradation by the cysteine proteinases, cathepsins B, B-like and L. Digestion of collagen IV, laminin, fibronectin, and release of gelatinase activities from basement membrane fibronectin by Guinec, N, Dalet-Fumeron, V, Pagano, M

“…We have studied the soluble fragments obtained from bovine lens capsules after digestion by the cysteine proteinases cathepsins B, B-like and L. These…”
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The Synthesis and Utilization of 2,4-Dinitrophenyl-Labeled Irreversible Peptidyl Diazomethyl Ketone Inhibitors by Hawthorne, Susan J., Pagano, Maurice, Harriott, Patrick, Halton, David W., Walker, Brian

“…Biotinylated diazomethyl ketones have been much used to detect cysteine proteases on Western blots, but high background may occur due to the presence of…”
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Expression of collagenase/gelatinase activity from basement‐membrane fibronectin by Boudjennah, Laziz, Dalet‐Fumeron, Véronique, Pagano, Maurice

“…We have isolated the collagenase/gelatinase activity of fibronectin from a bovine lens capsule hydrolysate, using heparin‐agarose, gelatin‐agarose,…”
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Immunopurification and characterization of a collagenase/gelatinase domain issued from basement membrane fibronectin by Boudjennah, Laziz, Dalet-Fumeron, Véronique, Ylätupa, Sari, Pagano, Maurice

“…The proteolytic potential of cellular fibronectin fragments issued from a basement membrane hydrolysate was investigated. Three different gelatinase activities…”
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