Search Results - "Pagano, Joseph J."

Multidisciplinary Approach to Novel Therapies in Cardio-Oncology Research (MANTICORE 101-Breast): A Randomized Trial for the Prevention of Trastuzumab-Associated Cardiotoxicity by Pituskin, Edith, Mackey, John R, Koshman, Sheri, Jassal, Davinder, Pitz, Marshall, Haykowsky, Mark J, Pagano, Joseph J, Chow, Kelvin, Thompson, Richard B, Vos, Larissa J, Ghosh, Sunita, Oudit, Gavin Y, Ezekowitz, Justin A, Paterson, D Ian

“…Purpose The primary toxicity of trastuzumab therapy for human epidermal growth factor receptor 2-overexpressing (HER2-positive) breast cancer is…”
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Reduced Right Ventricular Native Myocardial T1 in Anderson-Fabry Disease: Comparison to Pulmonary Hypertension and Healthy Controls by Pagano, Joseph J, Chow, Kelvin, Khan, Aneal, Michelakis, Evangelos, Paterson, Ian, Oudit, Gavin Y, Thompson, Richard B

“…Anderson-Fabry disease (AFD) is characterized by progressive multiorgan accumulation of intracellular sphingolipids due to α-galactosidase A enzyme deficiency,…”
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Increased extracellular volume in the liver of pediatric Fontan patients by de Lange, Charlotte, Reichert, Marjolein J E, Pagano, Joseph J, Seed, Mike, Yoo, Shi-Joon, Broberg, Craig S, Lam, Christopher Z, Grosse-Wortmann, Lars

“…Patients with single ventricle physiology are at increased risk for developing liver fibrosis. Its extent and prevalence in children with bidirectional…”
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Layer-specific strain in patients with heart failure using cardiovascular magnetic resonance: not all layers are the same by Xu, Lingyu, Pagano, Joseph J, Haykowksy, Mark J, Ezekowitz, Justin A, Oudit, Gavin Y, Mikami, Yoko, Howarth, Andrew, White, James A, Dyck, Jason R B, Anderson, Todd, Paterson, D Ian, Thompson, Richard B

“…Global longitudinal strain (GLS), most commonly measured at the endocardium, has been shown to be superior to left ventricular (LV) ejection fraction (LVEF)…”
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Quantification of lung water in heart failure using cardiovascular magnetic resonance imaging by Thompson, Richard B, Chow, Kelvin, Pagano, Joseph J, Sekowski, Viktor, Michelakis, Evangelos D, Tymchak, Wayne, Haykowsky, Mark J, Ezekowitz, Justin A, Oudit, Gavin Y, Dyck, Jason R B, Kaul, Padma, Savu, Anamaria, Paterson, D Ian

“…Pulmonary edema is a cardinal feature of heart failure but no quantitative tests are available in clinical practice. The goals of this study were to develop a…”
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Rationale and design of the Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research Trial (MANTICORE 101--Breast): a randomized, placebo-controlled trial to determine if conventional heart failure pharmacotherapy can prevent trastuzumab-mediated left ventricular remodeling among patients with HER2+ early breast cancer using cardiac MRI by Pituskin, Edith, Haykowsky, Mark, Mackey, John R, Thompson, Richard B, Ezekowitz, Justin, Koshman, Sheri, Oudit, Gavin, Chow, Kelvin, Pagano, Joseph J, Paterson, Ian

“…MANTICORE 101 - Breast (Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research) is a randomized trial to determine if conventional heart…”
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Cardiac and cardiometabolic phenotyping of trastuzumab-mediated cardiotoxicity: a secondary analysis of the MANTICORE trial by Kirkham, Amy A, Pituskin, Edith, Thompson, Richard B, Mackey, John R, Koshman, Sheri L, Jassal, Davinder, Pitz, Marshall, Haykowsky, Mark J, Pagano, Joseph J, Chow, Kelvin, Tsui, Albert K, Ezekowitz, Justin A, Oudit, Gavin Y, Paterson, D Ian

“…Abstract Aims An improved understanding of the pathophysiology of trastuzumab-mediated cardiotoxicity is required to improve outcomes of patients with human…”
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Differential Responses of Post-Exercise Recovery of Leg Blood Flow and Oxygen Uptake Kinetics in HFpEF versus HFrEF by Thompson, Richard B, Pagano, Joseph J, Mathewson, Kory W, Paterson, Ian, Dyck, Jason R, Kitzman, Dalane W, Haykowsky, Mark J

“…The goals of the current study were to compare leg blood flow, oxygen extraction and oxygen uptake (VO2) after constant load sub-maximal unilateral knee…”
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Normative Data for Myocardial Native T1 and Extracellular Volume Fraction in Children by Pagano, Joseph J, Yim, Deane, Lam, Christopher Z, Yoo, Shi-Joon, Seed, Mike, Grosse-Wortmann, Lars

“…To establish normative data for myocardial T1, including extracellular volume (ECV) fraction, in healthy children. In this retrospective, single-center study,…”
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Simultaneous proton density fat‐fraction and R2∗ imaging with water‐specific T1 mapping (PROFIT1): application in liver by Thompson, Richard B., Chow, Kelvin, Mager, Diana, Pagano, Joseph J., Grenier, Justin

“…Purpose To describe and validate a simultaneous proton density fat‐fraction (PDFF) imaging and water‐specific T1 mapping (T1(Water)) approach for the liver…”
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Saturation recovery single-shot acquisition (SASHA) for myocardial T1 mapping by Chow, Kelvin, Flewitt, Jacqueline A., Green, Jordin D., Pagano, Joseph J., Friedrich, Matthias G., Thompson, Richard B.

“…Purpose To validate a new saturation recovery single‐shot acquisition (SASHA) pulse sequence for T1 mapping and to compare SASHA T1 values in heart failure…”
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Natural History of Secundum ASD in Preterm and Term Neonates: A Comparative Study by Heidari, Negar, Kumaran, Kumar, Pagano, Joseph J., Hornberger, Lisa K.

“…Atrial septal defects (ASDs) are common in neonates. Although past studies suggest ASDs  ≥ 3 mm in term neonates (TNs) are less likely to close, there is…”
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Improved accuracy and precision with three‐parameter simultaneous myocardial T1 and T2 mapping using multiparametric SASHA by Chow, Kelvin, Hayes, Genevieve, Flewitt, Jacqueline A., Feuchter, Patricia, Lydell, Carmen, Howarth, Andrew, Pagano, Joseph J., Thompson, Richard B., Kellman, Peter, White, James A.

“…Purpose To develop and validate a three‐parameter model for improved precision multiparametric SAturation‐recovery single‐SHot Acquisition (mSASHA) cardiac T1…”
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Diffuse myocardial fibrosis by T1-mapping in children with subclinical anthracycline cardiotoxicity: relationship to exercise capacity, cumulative dose and remodeling by Tham, Edythe B, Haykowsky, Mark J, Chow, Kelvin, Spavor, Maria, Kaneko, Sachie, Khoo, Nee S, Pagano, Joseph J, Mackie, Andrew S, Thompson, Richard B

“…The late cardiotoxic effects of anthracycline chemotherapy influence morbidity and mortality in the growing population of childhood cancer survivors. Even with…”
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Improved accuracy and precision with three-parameter simultaneous myocardial T 1 and T 2 mapping using multiparametric SASHA by Chow, Kelvin, Hayes, Genevieve, Flewitt, Jacqueline A, Feuchter, Patricia, Lydell, Carmen, Howarth, Andrew, Pagano, Joseph J, Thompson, Richard B, Kellman, Peter, White, James A

“…To develop and validate a three-parameter model for improved precision multiparametric SAturation-recovery single-SHot Acquisition (mSASHA) cardiac T and T…”
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Imaging contrast agent concentration and extracellular volume fraction in the right ventricle by Pagano, Joseph J, Chow, Kelvin, Paterson, Ian, Thompson, Richard B

“…CLAIR image (left) at end-systole (1.17 mm resolution, 46 ms temporal resolution) and conventional T1-mapping image at end-diastole (right) (1.88 mm…”
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Diffuse Myocardial Fibrosis in Children and Adolescents With Marfan Syndrome and Loeys-Dietz Syndrome by Karur, Gauri R., Pagano, Joseph J., Bradley, Timothy, Lam, Christopher Z., Seed, Mike, Yoo, Shi-Joon, Grosse-Wortmann, Lars

“…Losartan, by interfering with transforming growth factor-β signaling pathways and causing extracellular signal-regulated kinase inhibition, has shown…”
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Cardiac Magnetic Resonance Imaging in Individuals With Prenatal Alcohol Exposure by Beaulieu, Danielle, Treit, Sarah, Pagano, Joseph J., Beaulieu, Christian, Thompson, Richard

“…Prenatal alcohol exposure (PAE) has teratogenic effects on numerous body systems including the heart. However, research magnetic resonance imaging (MRI)…”
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Effect of anthracycline therapy on myocardial function and markers of fibrotic remodelling in childhood cancer survivors by Mawad, Wadi, Mertens, Luc, Pagano, Joseph J, Riesenkampff, Eugenie, Reichert, Marjolein J E, Mital, Seema, Kantor, Paul F, Greenberg, Mark, Liu, Peter, Nathan, Paul C, Grosse-Wortmann, Lars

“…Abstract Aims Anthracyclines are a cornerstone of paediatric cancer treatment. We aimed to quantify myocardial cardiac magnetic resonance (CMR) native T1 (NT1)…”
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T1 mapping of the myocardium and liver in the single ventricle population by Beigh, Mirza V. R., Pajunen, Kiera B. E., Pagano, Joseph J., Olugbuyi, Oluwayomi, Harake, Danielle E., Noga, Michelle L., Tham, Edythe B.

“…Background Fontan associated liver disease (FALD) is an increasingly recognized complication of the single ventricle circulation characterized by hepatic…”
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