Search Results - "Paganelli, Franck"

Clinical Features, Management, and Outcomes of Immune Checkpoint Inhibitor-Related Cardiotoxicity by Escudier, Marion, Cautela, Jennifer, Malissen, Nausicaa, Ancedy, Yann, Orabona, Morgane, Pinto, Johan, Monestier, Sandrine, Grob, Jean-Jacques, Scemama, Ugo, Jacquier, Alexis, Lalevee, Nathalie, Barraud, Jeremie, Peyrol, Michael, Laine, Marc, Bonello, Laurent, Paganelli, Franck, Cohen, Ariel, Barlesi, Fabrice, Ederhy, Stephane, Thuny, Franck

“…Immune checkpoint inhibitors (ICIs) represent a major advance in the treatment of cancer. Although clinical trials reported a low incidence of immune-related…”
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Hyperhomocysteinemia and Cardiovascular Disease: Is the Adenosinergic System the Missing Link? by Paganelli, Franck, Mottola, Giovanna, Fromonot, Julien, Marlinge, Marion, Deharo, Pierre, Guieu, Régis, Ruf, Jean

“…The influence of hyperhomocysteinemia (HHCy) on cardiovascular disease (CVD) remains unclear. HHCy is associated with inflammation and atherosclerosis, and it…”
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Ticagrelor Increases Adenosine Plasma Concentration in Patients With an Acute Coronary Syndrome by Bonello, Laurent, MD, PhD, Laine, Marc, MD, Kipson, Nathalie, BSc, Mancini, Julien, MD, PhD, Helal, Olfa, PhD, Fromonot, Julien, MD, Gariboldi, Vlad, MD, Condo, Jocelyne, BSc, Thuny, Franck, MD, PhD, Frere, Corinne, MD, PhD, Camoin-Jau, Laurence, MD, PhD, Paganelli, Franck, MD, PhD, Dignat-George, Françoise, MD, PhD, Guieu, Regis, MD, PhD

“…Objectives This study aimed to investigate the impact of ticagrelor on adenosine plasma concentration (APC) in acute coronary syndrome (ACS) patients…”
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High On-Treatment Platelet Reactivity After Prasugrel Loading Dose and Cardiovascular Events After Percutaneous Coronary Intervention in Acute Coronary Syndromes by Bonello, Laurent, MD, Pansieri, Michel, MD, Mancini, Julien, MD, Bonello, Roland, MD, Maillard, Luc, MD, Barnay, Pierre, MD, Rossi, Philippe, MD, Ait-Mokhtar, Omar, MD, Jouve, Bernard, MD, Collet, Frederic, MD, Peyre, Jean Pascal, MD, Wittenberg, Olivier, MD, de Labriolle, Axel, MD, Camilleri, Elise, MD, Cheneau, Edouard, MD, Cabassome, Elma, MD, Dignat-George, Françoise, PhD, Camoin-Jau, Laurence, PhD, Paganelli, Franck, MD

“…Objectives The aim of this study was to investigate the relationship between platelet reactivity (PR) after a loading dose (LD) of prasugrel and thrombotic…”
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Tailored Clopidogrel Loading Dose According to Platelet Reactivity Monitoring to Prevent Acute and Subacute Stent Thrombosis by Bonello, Laurent, MD, Camoin-Jau, Laurence, PhD, Armero, Sébastien, MD, Com, Olivier, MD, Arques, Stéphane, MD, Burignat-Bonello, Caroline, MD, Giacomoni, Marie-Paule, MD, Bonello, Roland, MD, Collet, Frédéric, MD, Rossi, Philippe, MD, Barragan, Paul, MD, Dignat-George, Françoise, PhD, Paganelli, Franck, MD

“…Stent thrombosis remains a significant pitfall of percutaneous coronary intervention (PCI). A recent trial observed that an adjusted loading dose (LD) of…”
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Intensified immunosuppressive therapy in patients with immune checkpoint inhibitor-induced myocarditis by Cautela, Jennifer, Zeriouh, Sarah, Gaubert, Melanie, Bonello, Laurent, Laine, Marc, Peyrol, Michael, Paganelli, Franck, Lalevee, Nathalie, Barlesi, Fabrice, Thuny, Franck

“…BackgroundMyocarditis is a rare but life-threatening adverse event of cancer treatments with immune checkpoint inhibitors (ICIs). Recent guidelines recommend…”
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Emerging role of Raoultella ornithinolytica in human infections: a series of cases and review of the literature by Seng, Piseth, Boushab, Boushab Mohamed, Romain, Fanny, Gouriet, Frédérique, Bruder, Nicolas, Martin, Claude, Paganelli, Franck, Bernit, Emmanuelle, Treut, Yves Patrice Le, Thomas, Pascal, Papazian, Laurent, Raoult, Didier, Stein, Andreas

“…Graphical abstract…”
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Diagnostic Value of the International Society of Cardio-Oncology Definition for Suspected Immune Checkpoint Inhibitor-Associated Myocarditis by Deharo, Francois, Thuny, Franck, Cadour, Farah, Resseguier, Noemie, Meilhac, Alexandra, Gaubert, Melanie, Dolladille, Charles, Paganelli, Franck, Alexandre, Joachim, Cautela, Jennifer

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Adenosine Receptor Reserve and Long-Term Potentiation: Unconventional Adaptive Mechanisms in Cardiovascular Diseases? by Guieu, Régis, Brignole, Michele, Deharo, Jean Claude, Deharo, Pierre, Mottola, Giovanna, Groppelli, Antonella, Paganelli, Franck, Ruf, Jean

“…While the concept of a receptor reserve (spare receptors) is old, their presence on human cells as an adaptive mechanism in cardiovascular disease is a new…”
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Adenosine and Its Receptors: An Expected Tool for the Diagnosis and Treatment of Coronary Artery and Ischemic Heart Diseases by Gaudry, Marine, Vairo, Donato, Marlinge, Marion, Gaubert, Melanie, Guiol, Claire, Mottola, Giovanna, Gariboldi, Vlad, Deharo, Pierre, Sadrin, Stéphane, Maixent, Jean Michel, Fenouillet, Emmanuel, Ruf, Jean, Guieu, Regis, Paganelli, Franck

“…Adenosine is an endogenous nucleoside which strongly impacts the cardiovascular system. Adenosine is released mostly by endothelial cells and myocytes during…”
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P2Y12-ADP receptor antagonists: Days of future and past by Laine, Marc, Paganelli, Franck, Bonello, Laurent

“…Antiplatelet therapy is the cornerstone of the therapeutic arsenal in coronary artery disease.Thanks to a better understanding in physiology,pharmacology and…”
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Relation of Body Mass Index to High On-Treatment Platelet Reactivity and of Failed Clopidogrel Dose Adjustment According to Platelet Reactivity Monitoring in Patients Undergoing Percutaneous Coronary Intervention by Bonello-Palot, Nathalie, MD, Armero, Sébastien, MD, Paganelli, Franck, MD, Mancini, Julien, MD, De Labriolle, Axel, MD, Bonello, Caroline, MD, Lévy, Nicolas, MD, PhD, Maillard, Luc, MD, Barragan, Paul, MD, Dignat-George, Françoise, PhD, Camoin-Jau, Laurence, PhD, Bonello, Laurent, MD

“…High on-treatment platelet reactivity (HTPR) after a clopidogrel loading dose predicts the risk of thrombotic events after percutaneous coronary intervention…”
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Management and Research in Cancer Treatment-Related Cardiovascular Toxicity: Challenges and Perspectives by Cautela, Jennifer, Lalevee, Nathalie, Ammar, Chloé, Ederhy, Stéphane, Peyrol, Michael, Debourdeau, Philippe, Serin, Daniel, Le Dolley, Yvan, Michel, Nicolas, Orabona, Morgane, Barraud, Jérémie, Laine, Marc, Bonello, Laurent, Paganelli, Franck, Barlési, Fabrice, Thuny, Franck

“…Abstract Cardiovascular toxicity is a potentially serious complication that can result from the use of various cancer therapies and can impact the short- and…”
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Clopidogrel Loading Dose Adjustment According to Platelet Reactivity Monitoring in Patients Carrying the 2C192 Loss of Function Polymorphism by Bonello, Laurent, MD, Armero, Sébastien, MD, Ait Mokhtar, Omar, MD, Mancini, Julien, PhD, Aldebert, Philippe, MD, Saut, Noémie, MD, Bonello, Nathalie, MD, Barragan, Paul, MD, Arques, Stéphane, MD, Giacomoni, Marie-Paule, MD, Bonello-Burignat, Caroline, MD, Bartholomei, Marie-Noelle, MD, Dignat-George, Françoise, PhD, Camoin-Jau, Laurence, PhD, Paganelli, Franck, MD

“…Objectives We aimed to investigate the biological impact of a tailored clopidogrel loading dose (LD) according to platelet reactivity monitoring in carriers of…”
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Comparison of Ticagrelor Versus Prasugrel to Prevent Periprocedural Myonecrosis in Acute Coronary Syndromes by Bonello, Laurent, MD, PhD, Laine, Marc, MD, Cluzel, Marion, MD, Frere, Corinne, MD, PhD, Mancini, Julien, MD, PhD, Hasan, Aurasse, MD, Thuny, Franck, MD, PhD, Gaubert, Mélanie, MD, Guieu, Régis, MD, PhD, Dignat-George, Françoise, PhD, Michelet, Pierre, MD, PhD, Paganelli, Franck, MD, PhD, Kerbaul, François, MD, PhD

“…Guidelines recommend a ticagrelor loading dose (LD) before PCI or a prasugrel LD at the time of percutaneous coronary intervention (PCI) in intermediate and…”
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Impact of Neuroeffector Adrenergic Receptor Polymorphisms on Incident Ventricular Fibrillation During Acute Myocardial Ischemia by Chevalier, Philippe, Roy, Pascal, Bessière, Francis, Morel, Elodie, Ankou, Bénédicte, Morgan, Gina, Halder, Indrani, London, Barry, Minobe, Wayne A, Slavov, Dobromir, Delinière, Antoine, Bochaton, Thomas, Paganelli, Franck, Lesavre, Nathalie, Boiteux, Clément, Mansourati, Jacques, Maury, Philippe, Clerici, Gaël, Winum, Pierre François, Huebler, Sophia P, Carroll, Ian A, Bristow, Michael R

“…Background Cardiac adrenergic receptor gene polymorphisms have the potential to influence risk of developing ventricular fibrillation (VF) during…”
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Specific Pharmacological Profile of A2A Adenosine Receptor Predicts Reduced Fractional Flow Reserve in Patients With Suspected Coronary Artery Disease by Paganelli, Franck, Resseguier, Noémie, Marlinge, Marion, Laine, Marc, Malergue, Fabrice, Kipson, Nathalie, Armangau, Pauline, Pezzoli, Nicolas, Kerbaul, Francois, Bonello, Laurent, Mottola, Giovanna, Fenouillet, Emmanuel, Guieu, Régis, Ruf, Jean

“…Background The rapid and reliable exclusion of myocardial revascularization is a major unmet clinical need in patients with suspected coronary artery disease…”
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Antithrombotic efficacy of bivalirudin compared to unfractionated heparin during percutaneous coronary intervention for acute coronary syndrome by Frere, Corinne, Laine, Marc, Lemesle, Gilles, Morange, Pierre-Emmanuel, Paganelli, Franck, Dignat-George, Francoise, Resseguier, Noemie, Guieu, Regis, Camoin-Jau, Laurence, Bonello, Laurent

“…Bivalirudin is associated with an increased risk of acute stent thrombosis (AST) compared to unfractionated heparin (UFH) in acute coronary syndrome patients…”
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Vagal Reactions during Cryoballoon-Based Pulmonary Vein Isolation: A Clue for Autonomic Nervous System Modulation? by Franceschi, Frederic, Paganelli, Franck, Martinez, Elisa, Trevisan, Lory, Maille, Baptiste, Koutbi, Linda, Barraud, Jérémie, Peyrol, Michaël, Lévy, Samuel

“…Although paroxysmal atrial fibrillation (AF) is known to be initiated by rapid firing of pulmonary veins (PV) and non-PV triggers, the crucial role of cardiac…”
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Ticagrelor Improves Peripheral Arterial Function in Acute Coronary Syndrome Patients by Fromonot, Julien, PhD, Dignat-Georges, Françoise, PhD, Rossi, Pascal, MD, PhD, Mottola, Giovanna, PhD, Kipson, Nathalie, BSc, Ruf, Jean, PhD, Bonello, Laurent, MD, PhD, Guieu, Régis, MD, PhD, Paganelli, Franck, MD

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