Search Results - "Pagan, L."

Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease: A Phase 2 Randomized Clinical Trial by Pagan, Fernando L, Hebron, Michaeline L, Wilmarth, Barbara, Torres-Yaghi, Yasar, Lawler, Abigail, Mundel, Elizabeth E, Yusuf, Nadia, Starr, Nathan J, Anjum, Muhammad, Arellano, Joy, Howard, Helen H, Shi, Wangke, Mulki, Sanjana, Kurd-Misto, Tarick, Matar, Sara, Liu, Xiaoguang, Ahn, Jaeil, Moussa, Charbel

“…This study evaluated nilotinib safety and its effects on biomarkers as a potential disease-modifying drug in Parkinson disease. To assess nilotinib effects on…”
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Long‐Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease by Pagan, Fernando L., Wilmarth, Barbara, Torres‐Yaghi, Yasar, Hebron, Michaeline L., Mulki, Sanjana, Ferrante, Dalila, Matar, Sara, Ahn, Jaeil, Moussa, Charbel

“…ABSTRACT Background Nilotinib is US Food and Drug Administration–approved for leukemia, and this open‐label study investigated the safety, tolerability, and…”
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Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus by Gimenes, R, Gimenes, C, Rosa, C M, Xavier, N P, Campos, D H S, Fernandes, A A H, Cezar, M D M, Guirado, G N, Pagan, L U, Chaer, I D, Fernandes, D C, Laurindo, F R, Cicogna, A C, Okoshi, M P, Okoshi, K

“…Increased reactive oxygen species (ROS) generation in diabetes mellitus (DM) is an important mechanism leading to diabetic cardiomyopathy. Apocynin, a drug…”
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Clinical Use of On-Demand Therapies for Patients with Parkinson’s Disease and OFF Periods by Pahwa, Rajesh, Pagan, Fernando L., Kremens, Daniel E., Saint-Hilaire, Marie

“…On-demand therapies for Parkinson’s disease (PD) provide rapid, reliable relief for patients experiencing OFF periods; however, practical guidelines on the use…”
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Should “on-demand” treatments for Parkinson’s disease OFF episodes be used earlier? by Isaacson, Stuart H., Pagan, Fernando L., Lew, Mark F., Pahwa, Rajesh

“…•OFF episodes are common in patients as Parkinson’s disease progresses.•OFF episodes are typically managed with “ON-extenders” and changes in levodopa…”
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Results of a randomized, placebo‐controlled, first‐in‐human trial of topical CY‐002 in patients with cutaneous warts by Pagan, L., Yfanti, C., Rijneveld, R., Todd, M., Jongste, P., Feijen, J.J., Klaassen, E.S., Bouwes Bavinck, J.N., Struijk, L., Koning, M.N.C., Prestegarden, L., Niemeyer‐van der Kolk, T., Poelgeest, M.I.E., Rissmann, R.

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Safety, target engagement, and biomarker effects of bosutinib in dementia with Lewy bodies by Pagan, Fernando L., Torres‐Yaghi, Yasar, Hebron, Michaeline L., Wilmarth, Barbara, Turner, R. Scott, Matar, Sara, Ferrante, Dalila, Ahn, Jaeil, Moussa, Charbel

“…Introduction Bosutinib, a dual Abelson/Src inhibitor, was investigated in individuals with dementia with Lewy bodies (DLB). Methods A single site, randomized,…”
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Stereophotogrammetric three‐dimensional photography is an accurate and precise planimetric method for the clinical visualization and quantification of human papilloma virus‐induced skin lesions by Rijsbergen, M., Pagan, L., Niemeyer ‐ van der Kolk, T., Rijneveld, R., Hogendoorn, G., Lemoine, C., Meija Miranda, Y., Feiss, G., Bouwes Bavink, J.N., Burggraaf, J., van Poelgeest, M.I.E., Rissmann, R.

“…Background The quantification of human papilloma virus (HPV)‐induced skin lesions is essential for the clinical assessment of the course of disease and the…”
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Comparative Effectiveness of Carbidopa/Levodopa Enteral Suspension and Deep Brain Stimulation on Pill Burden Reduction in Medicare Fee-for-Service Patients with Advanced Parkinson’s Disease by Soileau, Michael J., Pagan, Fernando L., Fasano, Alfonso, Rodriguez-Cruz, Ramon, Yan, Connie H., Gupta, Niodita R., Teigland, Christie L., Pulungan, Zulkarnain, Schinkel, Jill K., Kandukuri, Prasanna L., Ladhani, Omar A., Siddiqui, Mustafa S.

“…Introduction Complex polypharmacy regimens to manage persistent motor fluctuations result in significant pill burden for patients with advanced Parkinson’s…”
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No effect of topical digoxin and furosemide gel for patients with external anogenital warts by Rijsbergen, M., Rijneveld, R., Todd, M., Pagan, L., Feiss, G., de Koning, M.N.C., van Alewijk, D.C.J.G., Klaassen, E.S., Burggraaf, J., Rissmann, R., van Poelgeest, M.I.E.

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Typical values of z-resolution for different Digital Breast Tomosynthesis systems evaluated in a multicenter study by Dalmonte, S., Golinelli, P., Oberhofer, N., Strocchi, S., Rossetti, V., Berta, L., Porzio, M., Angelini, L., Paruccini, N., Villa, R., Bertolini, M., Delle Canne, S., Cavallari, M., D'Ercole, L., Guerra, G., Rosasco, R., Cannillo, B., D'Alessio, A., Di Nicola, E., Origgi, D., De Marco, P., Maldera, A., Scabbio, C., Rottoli, F., Castriconi, R., Lorenzini, E., Pasquali, G., Pietrobon, F., Bregant, P., Giovannini, G., Favuzza, V., Bruschi, A., D'Urso, D., Maestri, D., De Novellis, S., Fracassi, A., Boschiroli, L., Quattrocchi, M., Gilio, M.A., Roberto, E., Altabella, L., Califano, G., Cimmino, M.C., Bortoli, E., Deiana, E., Pagan, L., Berardi, P., Ardu, V., Azzeroni, R., Campoleoni, M., Ravaglia, V.

“…•Typical values of z-resolution for different Digital Breast Tomosynthesis systems.•Z-resolution appeared to be affected by angular range and reconstruction…”
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Gender Differences in Friends' Influences on Adolescent Drinking: A Genetic Epidemiological Study by Dick, Danielle M., Pagan, Jason L., Holliday, Candice, Viken, Richard, Pulkkinen, Lea, Kaprio, Jaakko, Rose, Richard J.

“…Background:  We use data from a population‐based twin study to examine the association between characteristics of the friendship group and adolescents’ own…”
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Changing Environmental Influences on Substance Use Across Development by Dick, Danielle M., Pagan, Jason L., Viken, Richard, Purcell, Shaun, Kaprio, Jaakko, Pulkkinen, Lea, Rose, Richard J.

“…In contrast to many phenotypes that have been studied using twin designs, substance use shows considerable evidence of environmental influence. Accordingly,…”
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Forgetting of Intentions in Demanding Situations Is Rapid by Einstein, Gilles O, McDaniel, Mark A, Williford, Carrie L, Pagan, Jason L, Dismukes, R. Key

“…Demanding work settings often require the deferral of intended actions. In 3 experiments, participants were to withhold a response until they encountered a…”
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Covalent Surface Modification of Ti3C2Tx MXene with Chemically Active Polymeric Ligands Producing Highly Conductive and Ordered Microstructure Films by Lee, Jacob T, Wyatt, Brian C, Davis, Gregory A, Masterson, Adrianna N, Pagan, Amber L, Shah, Archit, Anasori, Babak, Sardar, Rajesh

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Improving outcomes through early diagnosis of Parkinson's disease by Pagan, Fernando L

“…Current diagnostic modalities in Parkinson's disease (PD) are limited by the fact that they identify PD by the presence of motor symptoms; by this point, over…”
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Control of Follicle-Stimulating Hormone by Estradiol and the Inhibins: Critical Role of Estradiol at the Hypothalamus during the Luteal-Follicular Transition by Welt, Corrine K., Pagan, Yanira L., Smith, Patricia C., Rado, Kimberly B., Hall, Janet E.

“…To test the hypothesis that estradiol, inhibin A, and inhibin B contribute differentially to FSH negative feedback in specific phases of the menstrual cycle,…”
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A study of myocardial tomoscintigraphy by semi-quantitative analysis by Pagan, L, Cason, E, Zoboli, S, Fierro, G, Lucchi, G, Soavi, R, Berardi, P

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Medical device evaluation for operators' radiation protection in angiographic procedures of chronic total occlusion by Soavi, R, Berardi, P, Baroni, L, Nobile, G, Sangiorgio, P, Pagan, L

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Evaluation of essential tremor with multi-voxel magnetic resonance spectroscopy by PAGAN, Fernando L, BUTMAN, John A, DAMBROSIA, James M, HALLETT, Mark

“…The pathologic substrate of essential tremor (ET) remains unknown. The authors studied 10 patients with ET and 10 volunteers using a multislice MR spectroscopy…”
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