Search Results - "Pagala, Vishwajeeth R"

A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice by Hunt, Liam C., Stover, Jared, Haugen, Benard, Shaw, Timothy I., Li, Yuxin, Pagala, Vishwajeeth R., Finkelstein, David, Barton, Elisabeth R., Fan, Yiping, Labelle, Myriam, Peng, Junmin, Demontis, Fabio

“…Skeletal muscle cell (myofiber) atrophy is a detrimental component of aging and cancer that primarily results from muscle protein degradation via the…”
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Deep Profiling of Microgram-Scale Proteome by Tandem Mass Tag Mass Spectrometry by Liu, Danting, Yang, Shu, Kavdia, Kanisha, Sifford, Jeffrey M, Wu, Zhiping, Xie, Boer, Wang, Zhen, Pagala, Vishwajeeth R, Wang, Hong, Yu, Kaiwen, Dey, Kaushik Kumar, High, Anthony A, Serrano, Geidy E, Beach, Thomas G, Peng, Junmin

“…Tandem mass tag (TMT)-based mass spectrometry (MS) enables deep proteomic profiling of more than 10,000 proteins in complex biological samples but requires up…”
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Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) by Shaw, Timothy I., Dong, Li, Tian, Liqing, Qian, Chenxi, Liu, Yu, Ju, Bensheng, High, Anthony, Kavdia, Kanisha, Pagala, Vishwajeeth R., Shaner, Bridget, Pei, Deqing, Easton, John, Janke, Laura J., Porter, Shaina N., Ma, Xiaotu, Cheng, Cheng, Pruett-Miller, Shondra M., Choi, John, Yu, Jiyang, Peng, Junmin, Gu, Wei, Look, A. Thomas, Downing, James R., Zhang, Jinghui

“…USP7, which encodes a deubiquitylating enzyme, is among the most frequently mutated genes in pediatric T-ALL, with somatic heterozygous loss-of-function…”
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Proteomic Studies of the Intrinsically Unstructured Mammalian Proteome by Galea, Charles A, Pagala, Vishwajeeth R, Obenauer, John C, Park, Cheon-Gil, Slaughter, Clive A, Kriwacki, Richard W

“…Intrinsically unstructured proteins (IUPs) represent an important class of proteins primarily involved in cellular signaling and regulation. The aim of this…”
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Identification of a Multifunctional Binding Site on Ubc9p Required for Smt3p Conjugation by Bencsath, Kalman P., Podgorski, Michael S., Pagala, Vishwajeeth R., Slaughter, Clive A., Schulman, Brenda A.

“…Ubiquitin-like proteins (ub-lps) are conjugated by a conserved enzymatic pathway, involving ATP-dependent activation at the C terminus by an activating enzyme…”
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Dynamic Foxp3-chromatin interaction controls tunable Treg cell function by He, Minghong, Zong, Xinying, Xu, Beisi, Qi, Wenjie, Huang, Wenjun, Djekidel, Mohamed Nadhir, Zhang, Yang, Pagala, Vishwajeeth R, Li, Jun, Hao, Xiaolei, Guy, Clifford, Bai, Lu, Cross, Richard, Li, Chunliang, Peng, Junmin, Feng, Yongqiang

“…Nuclear factor Foxp3 determines regulatory T (Treg) cell fate and function via mechanisms that remain unclear. Here, we investigate the nature of…”
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Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations by Hunt, Liam C, Jiao, Jianqin, Wang, Yong-Dong, Finkelstein, David, Rao, Deepti, Curley, Michelle, Robles-Murguia, Maricela, Shirinifard, Abbas, Pagala, Vishwajeeth R, Peng, Junmin, Fan, Yiping, Demontis, Fabio

“…Organisms use endogenous clocks to adapt to the rhythmicity of the environment and to synchronize social activities. Although the circadian cycle is implicated…”
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Spectral Library Search Improves Assignment of TMT Labeled MS/MS Spectra by Shen, Jianqiao, Pagala, Vishwajeeth R, Breuer, Alex M, Peng, Junmin, Bin Ma, Wang, Xusheng

“…Tandem mass tag (TMT)-based liquid chromatography-tandem mass spectrometry (LC–MS/MS) is a proven approach for large-scale multiplexed protein quantification…”
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Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia by Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.

“…Rearrangments in Histone-lysine-N-methyltransferase 2A (KMT2Ar) are associated with pediatric, adult and therapy-induced acute leukemias. Infants with KMT2Ar…”
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Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia by Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.

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Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification by High, Anthony A, Tan, Haiyan, Pagala, Vishwajeeth R, Niu, Mingming, Cho, Ji-Hoon, Wang, Xusheng, Bai, Bing, Peng, Junmin

“…Many exceptional advances have been made in mass spectrometry (MS)-based proteomics, with particular technical progress in liquid chromatography (LC) coupled…”
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Quantitative protein analysis by mass spectrometry by Pagala, Vishwajeeth R, High, Anthony A, Wang, Xusheng, Tan, Haiyan, Kodali, Kiran, Mishra, Ashutosh, Kavdia, Kanisha, Xu, Yanji, Wu, Zhiping, Peng, Junmin

“…Mass spectrometry is one of the most sensitive methods in analytical chemistry, and its application in proteomics has been rapidly expanded after sequencing…”
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T cell epitope "hotspots" on the HIV Type 1 gp120 envelope protein overlap with tryptic fragments displayed by mass spectrometry by Brown, Scott A, Lockey, Timothy D, Slaughter, Clive, Slobod, Karen S, Surman, Sherri, Zirkel, Amy, Mishra, Ashutosh, Pagala, Vishwajeeth R, Coleclough, Chris, Doherty, Peter C, Hurwitz, Julia L

“…Our previous work has shown that immunodominant T-helper cell epitopes cluster within distinct fragments on a single face of the HIV envelope gp120 protein. We…”
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Deep Profiling of Proteome and Phosphoproteome by Isobaric Labeling, Extensive Liquid Chromatography, and Mass Spectrometry by Bai, B, Tan, H, Pagala, V R, High, A A, Ichhaporia, V P, Hendershot, L, Peng, J

“…Mass spectrometry-based proteomics has experienced an unprecedented advance in comprehensive analysis of proteins and posttranslational modifications, with…”
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Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification by High, Anthony A., Tan, Haiyan, Pagala, Vishwajeeth R., Niu, Mingming, Cho, Ji-Hoon, Wang, Xusheng, Bai, Bing, Peng, Junmin

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