Search Results - "Pagakis, Stamatis N."

Exploiting the Role of Hypoxia-Inducible Factor 1 and Pseudohypoxia in the Myelodysplastic Syndrome Pathophysiology by Stergiou, Ioanna E, Kambas, Konstantinos, Poulaki, Aikaterini, Giannouli, Stavroula, Katsila, Theodora, Dimitrakopoulou, Aglaia, Vidali, Veroniki, Mouchtouris, Vasileios, Kloukina, Ismini, Xingi, Evangelia, Pagakis, Stamatis N, Probert, Lesley, Patrinos, George P, Ritis, Konstantinos, Tzioufas, Athanasios G, Voulgarelis, Michael

“…Myelodysplastic syndromes (MDS) comprise a heterogeneous group of clonal hematopoietic stem (HSCs) and/or progenitor cells disorders. The established…”
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Modulation of Heterochromatin Protein 1 Dynamics in Primary Mammalian Cells by Festenstein, Richard, Pagakis, Stamatis N., Hiragami, Kyoko, Lyon, Debbie, Verreault, Alain, Sekkali, Belaid, Kioussis, Dimitris

“…Heterochromatin protein 1 (HP1β), a key component of condensed DNA, is strongly implicated in gene silencing and centromeric cohesion. Heterochromatin has been…”
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AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division by Pantazopoulou, Vasiliki I., Delis, Anastasios D., Georgiou, Stella, Pagakis, Stamatis N., Filippa, Vicky, Dragona, Eleni, Kloukina, Ismini, Chatzitheodoridis, Elias, Trebicka, Jonel, Velentzas, Athanassios D., Thiele, Maja, Gagos, Sarantis, Thanos, Dimitris, Tseleni-Balafouta, Sofia, Stravopodis, Dimitrios J., Anastasiadou, Ema

“…Argonaute 2 (AGO2) is an indispensable component of the RNA-induced silencing complex, operating at the translational or posttranscriptional level. It is…”
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Role of T and NK Cells and IL7/IL7r Interactions during Neonatal Maturation of Lymph Nodes by Coles, Mark C., Veiga-Fernandes, Henrique, Foster, Katie E., Norton, Trisha, Pagakis, Stamatis N., Seddon, Ben, Kioussis, Dimitris

“…Lymph node (LN) development depends on prenatal interactions occurring between LN inducer and LN organizer cells. We have distinguished defects in LN formation…”
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Vav1 transduces TCR signals required for LFA‐1 function and cell polarization at the immunological synapse by Ardouin, Laurence, Bracke, Madelon, Mathiot, Anne, Pagakis, Stamatis N., Norton, Trisha, Hogg, Nancy, Tybulewicz, Victor L. J.

“…Activation of T lineage cells through the TCR by peptide–MHC complexes on APC is critically dependent on rearrangement of the actin cytoskeleton. Vav1 is a…”
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Differential intracellular trafficking of extracellular vesicles in microglia and astrocytes by Pantazopoulou, Marina, Lamprokostopoulou, Agaristi, Karampela, Dimitra Sotiria, Alexaki, Anastasia, Delis, Anastasios, Coens, Audrey, Samiotaki, Martina, Kriebardis, Anastasios G., Melki, Ronald, Pagakis, Stamatis N., Stefanis, Leonidas, Vekrellis, Kostas

“…Extracellular vesicles (EVs) have emerged as key players in cell-to-cell communication in both physiological and pathological processes in the Central Nervous…”
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Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming by Pateras, Ioannis S, Williams, Chloe, Gianniou, Despoina D, Margetis, Aggelos T, Avgeris, Margaritis, Rousakis, Pantelis, Legaki, Aigli-Ioanna, Mirtschink, Peter, Zhang, Wei, Panoutsopoulou, Konstantina, Delis, Anastasios D, Pagakis, Stamatis N, Tang, Wei, Ambs, Stefan, Warpman Berglund, Ulrika, Helleday, Thomas, Varvarigou, Anastasia, Chatzigeorgiou, Antonios, Nordström, Anders, Tsitsilonis, Ourania E, Trougakos, Ioannis P, Gilthorpe, Jonathan D, Frisan, Teresa

“…Chemotherapy (CT) is central to the treatment of triple negative breast cancer (TNBC), but drug toxicity and resistance place strong restrictions on treatment…”
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The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival by Vafiadaki, Elizabeth, Arvanitis, Demetrios A, Pagakis, Stamatis N, Papalouka, Vasiliki, Sanoudou, Despina, Kontrogianni-Konstantopoulos, Aikaterini, Kranias, Evangelia G

“…Cardiac contractility is regulated through the activity of various key Ca(2+)-handling proteins. The sarco(endo)plasmic reticulum (SR) Ca(2+) transport ATPase…”
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Lipid rafts: cell surface platforms for T cell signaling by Magee, Tony, Pirinen, Niina, Adler, Jeremy, Pagakis, Stamatis N, Parmryd, Ingela

“…The Src family tyrosine kinase Lck is essential for T cell development and T cell receptor (TCR) signaling. Lck is post-translationally fatty acylated at its…”
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Increased autophagy/mitophagy levels in primary tumours of patients with pancreatic neuroendocrine neoplasms by Daskalakis, Kosmas, Alexandraki, Krystallenia I., Kloukina, Ismini, Kassi, Evanthia, Felekouras, Evangelos, Xingi, Evangelia, Pagakis, Stamatis N., Tsolakis, Apostolos V., Andreakos, Evangelos, Kaltsas, Gregory, Kambas, Konstantinos

“…Background/aims We assessed the levels of autophagy and mitophagy, that are linked to cancer development and drug resistance, in well differentiated pancreatic…”
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Silicon scaffolds promoting three-dimensional neuronal web of cytoplasmic processes by Papadopoulou, Evie L, Samara, Athina, Barberoglou, Marios, Manousaki, Aleka, Pagakis, Stamatis N, Anastasiadou, Ema, Fotakis, Costas, Stratakis, Emmanuel

“…Primary neurons were grown on structured silicon (Si) substrates, in the absence of chemotropic factors or synthetic extracellular matrix. The Si substrates…”
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Application of two dimensional and three dimensional imaging techniques to frog microvessels in-situ loaded with fluorescent indicators by Pagakis, Stamatis N., Curry, Fitz-Roy E., Lenz, Joyce F.

“…A limitation of the photomultiplier tube (PMT) based quantitation systems in fluorescence microscopy is the lack of spatial information. In this paper, a…”
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