Search Results - "Pagé, Martine"
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Matrix metalloproteinase inhibition by green tea catechins
Published in Biochimica et biophysica acta (16-03-2000)“…We have investigated the effects of different biologically active components from natural products, including green tea polyphenols (GTP), resveratrol,…”
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Green tea polyphenol (−)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells
Published in Biochimica et biophysica acta (30-01-2002)“…We have recently shown that green tea polyphenols, and especially (−)-epigallocatechin 3-gallate (EGCg), acted as potent inhibitors of matrix metalloproteinase…”
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Synthesis and Evaluation of a Novel Nonsteroidal-Specific Endothelial Cell Proliferation Inhibitor
Published in Journal of medicinal chemistry (10-04-2003)“…The identification of agents with specific antiproliferative or cytostatic activity against endothelial cells has significant value for the treatment of…”
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A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells
Published in Molecular therapy. Methods & clinical development (13-03-2020)“…Chimeric antigen receptor (CAR) development involves extensive empirical characterization of antigen-binding domain (ABD)/CAR constructs for clinical…”
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De novo design, synthesis and evaluation of a non-steroidal diphenylnaphthyl propylene ligand for the estrogen receptor
Published in Bioorganic & medicinal chemistry (03-04-2003)“…There is still a strong need for additional diversity and new chemical scaffolds to allow for the exploration of improved tissue selectivity and finding better…”
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Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains
Published in Biochemical journal (01-02-2001)“…Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a membrane-associated MMP that has been recently reported to have a central role in tumour cell invasion…”
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Abstract 666: AB-3A4: A novel KAAG1-targeting antibody-drug conjugate is active in models of ovarian carcinoma, triple-negative breast cancer and castration-resistant prostate cancer
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Starting from total RNA prepared from late-stage serous ovarian tumors and low-malignancy potential tumors, a sensitive subtractive cloning technology called…”
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De Novo Design, Synthesis, and Evaluation of Novel Nonsteroidal Phenanthrene Ligands for the Estrogen Receptor
Published in Journal of medicinal chemistry (10-04-2003)“…Although there are many estrogen receptor antagonists with improved tissue selectivity profiles compared with tamoxifen, optimal tissue selectivity has not yet…”
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Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains
Published in Biochemical journal (01-02-2001)“…Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a membrane-associated MMP that has been recently reported to have a central role in tumour cell invasion…”
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Abstract 1467: AB-16B5, a therapeutic monoclonal antibody against human clusterin that blocks the epithelial-to-mesenchymal transition
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Studies are increasingly implicating clusterin (CLU) as an important contributing factor in cancer promotion and invasion. Although there is evidence that…”
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Rapid activation of matrix metalloproteinase-2 by glioma cells occurs through a posttranslational MT1-MMP-dependent mechanism
Published in Biochimica et biophysica acta (20-09-2000)“…Matrix metalloproteinase-2 (MMP-2) has been suggested to play a crucial role in tumor invasion and angiogenesis. In order to understand the mechanisms…”
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A Soluble Transforming Growth Factor-β (TGF-β) Type I Receptor Mimics TGF-β Responses
Published in The Journal of biological chemistry (07-12-2001)“…Transforming growth factor-β (TGF-β) signaling requires a ligand-dependent interaction of TGF-β receptors ΤβR-I and ΤβR-II. It has been previously demonstrated…”
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A Soluble Transforming Growth Factor-β (TGF-β) Type I Receptor Mimics TGF-β Responses
Published in The Journal of biological chemistry (07-12-2001)“…Transforming growth factor-β (TGF-β) signaling requires a ligand-dependent interaction of TGF-β receptors ΤβR-I and ΤβR-II. It has been previously…”
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