Search Results - "Padua, David"

Altered brain-gut axis in autism: Comorbidity or causative mechanisms? by Mayer, Emeran A., Padua, David, Tillisch, Kirsten

“…The concept that alterated communications between the gut microbiome and the brain may play an important role in human brain disorders has recently received…”
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TGF-β-Id1 Signaling Opposes Twist1 and Promotes Metastatic Colonization via a Mesenchymal-to-Epithelial Transition by Stankic, Marko, Pavlovic, Svetlana, Chin, Yvette, Brogi, Edi, Padua, David, Norton, Larry, Massagué, Joan, Benezra, Robert

“…ID genes are required for breast cancer colonization of the lungs, but the mechanism remains poorly understood. Here, we show that Id1 expression induces a…”
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The Pivotal Role of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers in Hypertension Management and Cardiovascular and Renal Protection: A Critical Appraisal and Comparison of International Guidelines by Alcocer, Luis Antonio, Bryce, Alfonso, De Padua Brasil, David, Lara, Joffre, Cortes, Javier Moreno, Quesada, Daniel, Rodriguez, Pablo

“…Arterial hypertension is the main preventable cause of premature mortality worldwide. Across Latin America, hypertension has an estimated prevalence of…”
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A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation by Padua, David, Mahurkar-Joshi, Swapna, Law, Ivy Ka Man, Polytarchou, Christos, Vu, John P, Pisegna, Joseph R, Shih, David, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

“…High-throughput technologies revealed new categories of genes, including the long noncoding RNAs (lncRNAs), involved in the pathogenesis of human disease;…”
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miR-24 Is Elevated in Ulcerative Colitis Patients and Regulates Intestinal Epithelial Barrier Function by Soroosh, Artin, Rankin, Carl R., Polytarchou, Christos, Lokhandwala, Zulfiqar A., Patel, Ami, Chang, Lin, Pothoulakis, Charalabos, Iliopoulos, Dimitrios, Padua, David M.

“…Inflammatory bowel disease is characterized by high levels of inflammation and loss of barrier integrity in the colon. The intestinal barrier is a dynamic…”
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Gastrointestinal Manifestations of Hereditary Hemorrhagic Telangiectasia (HHT): A Systematic Review of the Literature by Jackson, Samuel B., Villano, Nicholas P., Benhammou, Jihane N., Lewis, Michael, Pisegna, Joseph R., Padua, David

“…Hereditary hemorrhagic telangiectasia (HHT), also called Osler–Weber–Rendu syndrome, is an autosomal dominant genetic disease that affects the vasculature of…”
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Gene Expression Profiling Identifies CDKN2B-AS1 as a Long Non-Coding RNA Associated with IBD and Regulated by TGF-beta by Rankin, Carl R, Iliopoulos, Dimitrios, Pothoulakis, Charalabos, Padua, David M

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Long Non-Coding RNA (LNCRNA) Profiling Reveals Overexpression of UCA1 and CCAT1 in Human Colonocytes Stimulated by Neurotensin and in Colonic Mucosal Tissues from Ulcerative Colitis (UC) Patients by Law, Ivy Ka Man, Padua, David M, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

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Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation by Soroosh, Artin, Fang, Kai, Hoffman, Jill M., Law, Ivy K. M., Videlock, Elizabeth, Lokhandwala, Zulfiqar A., Zhao, Jonathan J., Hamidi, Sepehr, Padua, David M., Frey, Mark R., Pothoulakis, Charalabos, Rankin, Carl R.

“…While apoptosis plays a significant role in intestinal homeostasis, it can also be pathogenic if overactive during recovery from inflammation. We recently…”
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Lung metastasis genes couple breast tumor size and metastatic spread by Minn, Andy J, Gupta, Gaorav P, Padua, David, Bos, Paula, Nguyen, Don X, Nuyten, Dimitry, Kreike, Bas, Zhang, Yi, Wang, Yixin, Ishwaran, Hemant, Foekens, John A, van de Vijver, Marc, Massagué, Joan

“…The association between large tumor size and metastatic risk in a majority of clinical cancers has led to questions as to whether these observations are…”
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From High-Level Specification to High-Performance Code [Scanning the Issue] by Franchetti, Franz, Moura, Jose M. F., Padua, David A., Dongarra, Jack

“…Computer architectures and systems are becoming ever more powerful but increasingly more complex. With the end of frequency scaling (about 2004) and the era of…”
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A Challenging Case of Severe Ulcerative Colitis following the Initiation of Secukinumab for Ankylosing Spondylitis by Padua, David, Pisegna, Joseph R., Jamaluddin, Nimah, Ehrlich, Dean

“…Secukinumab is an interleukin-17 inhibitor used for the treatment of ankylosing spondylitis (AS), psoriasis, and psoriatic arthritis. The risk of exacerbating…”
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Correction: Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation by Soroosh, Artin, Fang, Kai, Hoffman, Jill M., Law, Ivy K. M., Videlock, Elizabeth, Lokhandwala, Zulfiqar A., Zhao, Jonathan J., Hamidi, Sepehr, Padua, David M., Frey, Mark R., Pothoulakis, Charalabos, Rankin, Carl R.

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Tu1839 miR-31-3p Is Involved in Substance P (SP)-Associated Inflammation in Human Colonic Epithelial Cells and Experimental Colitis by Fang, Kai, Law, Ivy Ka Man, Sideri, Aristea, Huang, Vanessa, Padua, David M, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

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129 Identification of a LncRNA Signature in Ulcerative Colitis: IFNG-AS1 Is a CD4+ T-Cell LncRNA Associated With IBD SNP Loci by Padua, David M, Mahurkar-Joshi, Swapna, Shih, David Q, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

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The Role of Neuropeptides in Mouse Models of Colitis by Padua, David, Vu, John P., Germano, Patrizia M., Pisegna, Joseph R.

“…Inflammatory bowel disease (IBD) constitutes an important clinically significant condition that results in morbidity and mortality. IBD can be generally…”
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Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation‐Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl‐Coenzyme A Desaturase As an Enhancer RNA by Benhammou, Jihane N., Ko, Arthur, Alvarez, Marcus, Kaikkonen, Minna U., Rankin, Carl, Garske, Kristina M., Padua, David, Bhagat, Yash, Kaminska, Dorota, Kärjä, Vesa, Pihlajamäki, Jussi, Pisegna, Joseph R., Pajukanta, Päivi

“…The global obesity epidemic is driving the concomitant rise in nonalcoholic fatty liver disease (NAFLD). To identify new genes involved in central liver…”
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The LRPD test: speculative run-time parallelization of loops with privatization and reduction parallelization by Rauchwerger, L., Padua, D.A.

“…Current parallelizing compilers cannot identify a significant fraction of parallelizable loops because they have complex or statically insufficiently defined…”
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Roles of TGFβ in metastasis by Padua, David, Massagué, Joan

“…The TGFβ signaling pathway is conserved from flies to humans and has been shown to regulate such diverse processes as cell proliferation, differentiation,…”
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Rare Finding of Partial Anomalous Pulmonary Venous Connection With an Intact Atrial Septum Presenting as Right Heart Failure and Pulmonary Hypertension in an Adult by Rana, Richie, MD, Padua, David, MD, Tennant, Rick, MD, Bierer, Greg, MD, Wallace, Jeanne, MD, Kamangar, Nader, MD

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