Search Results - "Padra, Médea"
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Structural Diversity of Human Gastric Mucin Glycans
Published in Molecular & cellular proteomics (01-05-2017)“…The mucin O-glycosylation of 10 individuals with and without gastric disease was examined in depth in order to generate a structural map of human gastric…”
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2
Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins
Published in Mucosal immunology (01-05-2019)“…Helicobacter suis is the most prevalent non- Helicobacter pylori Helicobacter species in the human stomach and is associated with chronic gastritis, peptic…”
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3
A novel quinoline with airway relaxant effects and anti-inflammatory properties
Published in Respiratory research (30-03-2024)“…In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unmet needs for improved treatment…”
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4
Macrophage expressed tartrate‐resistant acid phosphatase 5 promotes pulmonary fibrosis progression
Published in Immunology (01-04-2024)“…Idiopathic pulmonary fibrosis (IPF) is a progressive lung disorder involving scarring of pulmonary tissue and a subsequent decrease in respiratory capacity,…”
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5
IL-36 Cytokines Promote Inflammation in the Lungs of Long-Term Smokers
Published in American journal of respiratory cell and molecular biology (01-02-2021)“…Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory lung disease with high morbidity and mortality. The IL-36 family are proinflammatory…”
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Smoking-associated increase in mucins 1 and 4 in human airways
Published in Respiratory research (18-09-2020)“…Rationale Smoking-related chronic obstructive pulmonary disease (COPD) is associated with dysregulated production of mucus. Mucins (MUC) are important both for…”
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Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without COPD
Published in Glycobiology (Oxford) (30-12-2023)“…Abstract Chronic obstructive pulmonary disease (COPD) kills millions of people annually and patients suffering from exacerbations of this disorder display high…”
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Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD
Published in Journal of innate immunity (2020)“…There is incomplete mechanistic understanding of the mobilization of neutrophils in the systemic and local compartment in smokers with chronic obstructive…”
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Helicobacter suis binding to carbohydrates on human and porcine gastric mucins and glycolipids occurs via two modes
Published in Virulence (31-12-2018)“…Helicobacter suis colonizes the stomach of most pigs and is the most prevalent non-Helicobacter pylori Helicobacter species found in the human stomach. In the…”
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10
Mucus-Pathogen Interactions in the Gastrointestinal Tract of Farmed Animals
Published in Microorganisms (Basel) (18-06-2018)“…Gastrointestinal infections cause significant challenges and economic losses in animal husbandry. As pathogens becoming resistant to antibiotics are a growing…”
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A Complex Connection Between the Diversity of Human Gastric Mucin O-Glycans, Helicobacter pylori Binding, Helicobacter Infection and Fucosylation
Published in Molecular & cellular proteomics (01-11-2022)“…Helicobacter pylori colonizes the stomach of half of the human population. Most H. pylori are located in the mucus layer, which is mainly comprised by…”
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Mucin Binding to Moraxella catarrhalis during Airway Inflammation Is Dependent on Sialic Acid
Published in American journal of respiratory cell and molecular biology (01-12-2021)“…Chronic obstructive pulmonary disease (COPD) is associated with colonization by bacterial pathogens and repeated airway infections, leading to exacerbations…”
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13
Divergence between the Highly Virulent Zoonotic Pathogen Helicobacter heilmannii and Its Closest Relative, the Low-Virulence "Helicobacter ailurogastricus" sp. nov
Published in Infection and immunity (01-01-2016)“…Helicobacter heilmannii naturally colonizes the stomachs of dogs and cats and has been associated with gastric disorders in humans. Nine feline Helicobacter…”
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14
Structural diversity of human gastric mucin glycans
Published in Molecular & cellular proteomics (01-05-2017)“…The mucin O-glycosylation of 10 individuals with and without gastric disease was examined in depth in order to generate a structural map of human gastric…”
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15
BabA dependent binding of Helicobacter pylori to human gastric mucins cause aggregation that inhibits proliferation and is regulated via ArsS
Published in Scientific reports (20-01-2017)“…Mucins in the gastric mucus layer carry a range of glycan structures, which vary between individuals, can have antimicrobial effect or act as ligands for…”
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16
Influence of the viscosity of healthy and diseased human mucins on the motility of Helicobacter pylori
Published in Scientific reports (26-06-2018)“…We present particle tracking microrheology results on human mucins, isolated from normal surface and gland mucosa and one tumor sample, and examine the…”
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17
BabA-mediated adherence of pediatric ulcerogenic H. pylori strains to gastric mucins at neutral and acidic pH
Published in Virulence (01-01-2018)“…Helicobacter pylori infection can result in non-ulcer dyspepsia (NUD), peptic ulcer disease (PUD), adenocarcinoma, and gastric lymphoma. H. pylori reside…”
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Carbohydrate-Dependent and Antimicrobial Peptide Defence Mechanisms Against Helicobacter pylori Infections
Published in Current topics in microbiology and immunology (01-01-2019)“…The human stomach is a harsh and fluctuating environment for bacteria with hazards such as gastric acid and flow through of gastric contents into the…”
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19
Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
Published in International journal of chronic obstructive pulmonary disease (01-01-2022)“…Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are common comorbidities in chronic obstructive pulmonary disease (COPD), but the underlying…”
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Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains
Published in Frontiers in cellular and infection microbiology (17-06-2022)“…Streptococcus oralis is an oral commensal and opportunistic pathogen that can enter the bloodstream and cause bacteremia and infective endocarditis. Here, we…”
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