Search Results - "Padrón, Gabriel"

Proteomics studies on Protozoan Parasite Biology by Cuervo, Patricia, Padrón, Gabriel

Get full text

CIGB-300 anticancer peptide regulates the protein kinase CK2-dependent phosphoproteome by Perera, Yasser, Ramos, Yassel, Padrón, Gabriel, Caballero, Evelin, Guirola, Osmany, Caligiuri, Lorena G., Lorenzo, Norailys, Gottardo, Florencia, Farina, Hernán G., Filhol, Odile, Cochet, Claude, Perea, Silvio E.

“…Casein-kinase CK2 is a Ser/Thr protein kinase that fosters cell survival and proliferation of malignant cells. The CK2 holoenzyme, formed by the association of…”
Get full text

The OxyR and SoxR transcriptional regulators are involved in a broad oxidative stress response in Paraburkholderia xenovorans LB400 by Méndez, Valentina, Rodríguez-Castro, Laura, Durán, Roberto E, Padrón, Gabriel, Seeger, Michael

“…Aerobic metabolism generates reactive oxygen species that may cause critical harm to the cell. The aim of this study is the characterization of the stress…”
Get full text

The protein map of the protozoan parasite Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum during growth phase transition and temperature stress by Mule, Simon Ngao, Saad, Joyce Silva, Sauter, Ismael Pretto, Fernandes, Livia Rosa, de Oliveira, Gilberto Santos, Quina, Daniel, Tano, Fabia Tomie, Brandt-Almeida, Deborah, Padrón, Gabriel, Stolf, Beatriz Simonsen, Larsen, Martin R., Cortez, Mauro, Palmisano, Giuseppe

“…Leishmania parasites cause a spectrum of diseases termed leishmaniasis, which manifests in two main clinical forms, cutaneous and visceral leishmaniasis…”
Get full text

Biodistribution and pharmacokinetic profiles of an altered peptide ligand derived from heat-shock proteins 60 in Lewis rats by del Carmen Domínguez, María, Cabrales, Ania, Lorenzo, Norailys, Padrón, Gabriel, Gonzalez, L. J.

“…Human heat-shock protein 60 (HSP60) is an autoantigen involved in the pathogenesis of rheumatoid arthritis (RA). Epitopes derived from HSP60 can trigger…”
Get full text

Advancing Smart Home Awareness-A Conceptual Computational Modelling Framework for the Execution of Daily Activities of People with Alzheimer's Disease by Liappas, Nikolaos, Teriús-Padrón, José Gabriel, García-Betances, Rebeca Isabel, Cabrera-Umpiérrez, María Fernanda

“…Utilizing context-aware tools in smart homes (SH) helps to incorporate higher quality interaction paradigms between the house and specific groups of users such…”
Get full text

Quantitative analysis of proteins secreted by Leishmania (Viannia) braziliensis strains associated to distinct clinical manifestations of American Tegumentary Leishmaniasis by Rodríguez-Vega, Andrés, Losada-Barragán, Monica, Berbert, Luiz Ricardo, Mesquita-Rodrigues, Camila, Bombaça, Ana Cristina Souza, Menna-Barreto, Rubem, Aquino, Priscila, Carvalho, Paulo C., Padrón, Gabriel, de Jesus, Jose Batista, Cuervo, Patricia

“…The role of Leishmania braziliensis in the development of different clinical forms of American Tegumentary Leishmaniasis (ATL) is unclear, but it has been…”
Get full text

Empowering Citizens through Perceptual Sensing of Urban Environmental and Health Data Following a Participative Citizen Science Approach by Ottaviano, Manuel, Beltrán-Jaunsarás, María Eugenia, Teriús-Padrón, José Gabriel, García-Betances, Rebeca I, González-Martínez, Sergio, Cea, Gloria, Vera, Cecilia, Cabrera-Umpiérrez, María Fernanda, Waldmeyer, María Teresa Arredondo

“…The growth of the urban population together with a high concentration of air pollution have important health impacts on citizens who are exposed to them,…”
Get full text

Two decades of proteomics in Latin America: A personal view by Padrón, Gabriel, Domont, Gilberto B.

“…Proteomics is the charming young daughter of classical protein chemistry. It was conceived in 1975, year of invention of the first proteomic technique, the…”
Get full text

APL1, an altered peptide ligand derived from human heat-shock protein 60, increases the frequency of Tregs and its suppressive capacity against antigen responding effector CD4+T cells from rheumatoid arthritis patients by Barberá, Ariana, Lorenzo, Noraylis, van Kooten, Peter, van Roon, Joel, de Jager, Wilco, Prada, Dinorah, Gómez, Jorge, Padrón, Gabriel, van Eden, Willem, Broere, Femke, del Carmen Domínguez, María

“…Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by a chronic relapsing-remitting joint inflammation. Perturbations in the balance…”
Get full text

In-Depth Quantitative Proteomics Characterization of In Vitro Selected Miltefosine Resistance in Leishmania infantum by Saboia-Vahia, Leonardo, Cuervo, Patricia, Wiśniewski, Jacek R, Dias-Lopes, Geovane, Pinho, Nathalia, Padrón, Gabriel, de Pilla Varotti, Fernando, Murta, Silvane Maria Fonseca

“…Visceral leishmaniasis (VL) is a neglected disease caused by parasites. Although significant morbidity and mortality in tropical and subtropical regions of the…”
Get full text

Evaluation of Phenylthiocarbamoyl-Derivatized Peptides by Electrospray Ionization Mass Spectrometry: Selective Isolation and Analysis of Modified Multiply Charged Peptides for Liquid Chromatography−Tandem Mass Spectrometry Experiments by Sanchez, Aniel, Perez-Riverol, Yasset, González, Luis Javier, Noda, Jesus, Betancourt, Lazaro, Ramos, Yassel, Gil, Jeovanis, Vera, Roberto, Padrón, Gabriel, Besada, Vladimir

“…Edman degradation in the gas phase has been observed by collision activated dissociation of N-terminal phenylthiocarbamoyl (PTC) protonated peptide to yield…”
Get full text

An altered peptide ligand corresponding to a novel epitope from heat-shock protein 60 induces regulatory T cells and suppresses pathogenic response in an animal model of adjuvant-induced arthritis by Dominguez, Maria del Carmen, Lorenzo, Noraylis, Barbera, Ariana, Darrasse-Jeze, Guillaume, Hernández, Maria Victoria, Torres, Ana, Hernández, Isabel, Gil, Rafael, Klatzmann, David, Padrón, Gabriel

“…Induction of immune tolerance as therapeutic approach for autoimmune diseases constitutes a current research focal point. In this sense, we aimed to evaluate…”
Get full text

Development and validation of a bioanalytical LC–MS method for the quantification of GHRP-6 in human plasma by Gil, Jeovanis, Cabrales, Ania, Reyes, Osvaldo, Morera, Vivian, Betancourt, Lázaro, Sánchez, Aniel, García, Gerardo, Moya, Galina, Padrón, Gabriel, Besada, Vladimir, González, Luis Javier

“…► A quantitative method for GHRP-6 in human plasma was developed and fully validated. ► 13C-labeled Alanine GHRP-6 as internal standard allowed relative…”
Get full text

Isoelectric point optimization using peptide descriptors and support vector machines by Perez-Riverol, Yasset, Audain, Enrique, Millan, Aleli, Ramos, Yassel, Sanchez, Aniel, Vizcaíno, Juan Antonio, Wang, Rui, Müller, Markus, Machado, Yoan J., Betancourt, Lazaro H., González, Luis J., Padrón, Gabriel, Besada, Vladimir

“…IPG (Immobilized pH Gradient) based separations are frequently used as the first step in shotgun proteomics methods; it yields an increase in both the dynamic…”
Get full text

Proteomics reveals major components of oogenesis in the reproductive tract of sugar-fed Anopheles aquasalis by Dias-Lopes, Geovane, Borges-Veloso, Andre, Saboia-Vahia, Leonardo, Padrón, Gabriel, de Faria Castro, Cássia Luana, Guimarães, Ana Carolina Ramos, Britto, Constança, Cuervo, Patricia, De Jesus, Jose Batista

“…Anopheles (Nyssorhynchus) aquasalis is a malaria vector mainly distributed along the coastal regions of South and Central America. In the absence of an…”
Get full text

Peptide fractionation by acid pH SDS-free electrophoresis by Ramos, Yassel, Garcia, Yairet, Pérez-Riverol, Yasset, Leyva, Alejandro, Padrón, Gabriel, Sánchez, Aniel, Castellanos-Serra, Lila, González, Luis J., Besada, Vladimir

“…SDS‐free polyacrylamide gel electrophoresis is an effective alternative approach to peptide fractionation. Here we describe a discontinuous buffer system at…”
Get full text

Characterization of the interaction of domain III of the envelope protein of dengue virus with putative receptors from CHO cells by Huerta, Vivian, Chinea, Glay, Fleitas, Noralvis, Sarría, Mónica, Sánchez, Jorge, Toledo, Patricia, Padrón, Gabriel

“…Domain III (DIII) of the envelope protein of dengue virus (DENV) contains structural determinants for the interaction with cellular receptors. In the present…”
Get full text

APL-2, an altered peptide ligand derived from heat-shock protein 60, induces interleukin-10 in peripheral blood mononuclear cell derived from juvenile idiopathic arthritis patients and downregulates the inflammatory response in collagen-induced arthritis model by Lorenzo, Norailys, Cantera, Dolores, Barberá, Ariana, Alonso, Amaris, Chall, Elsy, Franco, Lourdes, Ancizar, Julio, Nuñez, Yanetsy, Altruda, Fiorella, Silengo, Lorenzo, Padrón, Gabriel, del Carmen Dominguez, Maria

“…Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases characterized by autoimmune arthritis of unknown cause with onset before age of…”
Get full text

Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers by Cabrales, Ania, Gil, Jeovanis, Fernández, Eduardo, Valenzuela, Carmen, Hernández, Francisco, García, Idrián, Hernández, Ariadna, Besada, Vladimir, Reyes, Osvaldo, Padrón, Gabriel, Berlanga, Jorge, Guillén, Gerardo, González, Luis Javier

“…GHRP-6 is a growth hormone secretagogue that also enhances tissue viability in different organs. In the present work, we studied the pharmacokinetics of this…”
Get full text