Search Results - "Padmanabhan, Swami"

Ofatumumab As Single-Agent CD20 Immunotherapy in Fludarabine-Refractory Chronic Lymphocytic Leukemia by Wierda, William G, Kipps, Thomas J, Mayer, Jirí, Stilgenbauer, Stephan, Williams, Cathy D, Hellmann, Andrzej, Robak, Tadeusz, Furman, Richard R, Hillmen, Peter, Trneny, Marek, Dyer, Martin J S, Padmanabhan, Swami, Piotrowska, Magdalena, Kozak, Tomas, Chan, Geoffrey, Davis, Randy, Losic, Nedjad, Wilms, Joris, Russell, Charlotte A, Osterborg, Anders

“…New treatments are needed for patients with fludarabine- and alemtuzumab-refractory (FA-ref) chronic lymphocytic leukemia (CLL) or patients with…”
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Ofatumumab monotherapy in fludarabine-refractory chronic lymphocytic leukemia: final results from a pivotal study by Österborg, Anders, Jewell, Roxanne C, Padmanabhan-Iyer, Swami, Kipps, Thomas J, Mayer, Jiří, Stilgenbauer, Stephan, Williams, Cathy D, Hellmann, Andrzej, Furman, Richard R, Robak, Tadeusz, Hillmen, Peter, Trnêný, Marek, Dyer, Martin J S, Piotrowska, Magdalena, Kozak, Tomas, Gupta, Ira V, Phillips, Jennifer L, Goldstein, Nancy, Struemper, Herbert, Losic, Nedjad, Lisby, Steen, Wierda, William G

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Current status of therapy for chronic myeloid leukemia: a review of drug development by Padmanabhan, Swami, Ravella, Saritha, Curiel, Tyler, Giles, Francis

“…Chronic myeloid leukemia (CML) has led the way for developing rational drug development in cancer. Most cases of CML diagnosed and treated in chronic phase are…”
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Protein Kinase C βII Plays an Essential Role in Dendritic Cell Differentiation and Autoregulates Its Own Expression by Cejas, Pedro J., Carlson, Louise M., Zhang, Jian, Padmanabhan, Swami, Kolonias, Despina, Lindner, Inna, Haley, Stephen, Boise, Lawrence H., Lee, Kelvin P.

“…Dendritic cells (DC) arise from a diverse group of hematopoietic progenitors and have marked phenotypic and functional heterogeneity. The signal transduction…”
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Analysis of Donor Age and Absolute Lymphocyte Count Recovery as Prognostic Indicators of Survival after Allogeneic Blood or Marrow Transplantation by Senfield, Jeffrey J., Hahn, Theresa, Padmanabhan, Swami, McCarthy, Philip L., Battiwalla, Minoo

“…Absolute lymphocyte count (ALC) recovery ≥500 cells/mL at day 15 or 30 post-autologous (autoBMT) transplantation has been reported in many studies as an…”
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The Adaptor Protein SLP-76 Is Not a Direct Substrate for BCR-ABL in the Chronic Myeloid Leukemia Cell Line K562 by Joseph, Witzard, Luckashenak, Nancy, Ramsey, Kimberly, Clements, James, Padmanabhan, Swami

“…SLP-76(SH2 domain-containing leukocyte protein of 76 kD) is a hematopoietic adapter protein that is expressed in myeloid and T cells. SLP-76 is a substrate for…”
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Incidence, Clinical Presentation and Outcome of Secondary Multiple Extramedullary Plasmacytomas: Experience at Roswell Park Cancer Institute by Manochakian, Rami, Miller, Kena C., Coignet, Jean-Gabriel, Padmanabhan, Swami, Musial, Laurie, DePaolo, Dawn, Chanan-Khan, Asher Alban

“…Introduction: Extramedullary plasmacytomas are malignant plasma cell tumors that arise outside of the bone marrow. They occur either as solitary tumors with a…”
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Aggressive relapse of multiple myeloma with intracerebral extension and associated hemorrhage by Reddy, Nishitha, Karampelas, Ioannis, Chanan-Khan, Asher, Fenstermaker, Robert, Padmanabhan, Swami

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Correlation Between Serum Ofatumumab Concentrations, Baseline Patient Characteristics and Clinical Outcomes in Patients with Fludarabine-Refractory Chronic Lymphocytic Leukemia (CLL) Treated with Single-Agent Ofatumumab by Österborg, Anders, Ronn, Birgitte Biilmann, Jewell, Roxanne C, Kipps, Thomas J, Mayer, Jiri, Stilgenbauer, Stephan, Williams, Cathy D, Hellmann, Andrzej, Robak, Tadeusz, Furman, Richard R, Hillmen, Peter, Trneny, Marek, Dyer, Martin JS, Padmanabhan, Swami, Piotrowska, Magdalena, Kozak, Tomas, Chan, Geoffrey, Arning, Michael, Losic, Nedjad, Davis, Randy, Wilms, Joris, Russell, Charlotte A, Wierda, William G

“…Abstract 3433 Poster Board III-321 Monoclonal antibody (mAb) therapies represent an important clinical advance for patients (pts) with CLL, yet little is known…”
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Pro-Apoptotic Effect of Lenalidomide (L) in Patients with Chronic Lymphocytic Leukemia (CLL) Is Possibly Mediated through Interruption of the Phosphatidylinositol Pathway by Chanan-Khan, Asher Alban, Ersing, Noreen, Krammer, Deborah, Bernacki, Ralph, Coignet, Lionel, Goodrich, David, Bangia, Naveen, Padmanabhan, Swami, Porter, Carl W.

“…Introduction: In a phase II clinical trial we reported the antileukemic effect of L in CLL pts. In this clinical trial 24/34 (70.5%) pts with detectable tumor…”
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Human leukocyte antigen DR4 is associated with inferior progression-free survival following allogeneic hematopoietic stem cell transplantation for lymphoid malignancies by Aggarwal, Charu, Gupta, Sameer, Hahn, Theresa, Smiley, Shannon, Padmanabhan, Swami, McCarthy, Philip L., Battiwalla, Minoo

“…The Class II human leukocyte antigen (HLA) DRB1 antigen DR4 is associated with autoimmune disorders and response to cyclosporine immunosuppression in…”
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Pharmacokinetic study of omacetaxine mepesuccinate administered subcutaneously to patients with advanced solid and hematologic tumors by Nemunaitis, John, Mita, Alain, Stephenson, Joe, Mita, Monica M., Sarantopoulos, John, Padmanabhan-Iyer, Swami, Nanda, Nisha, Gleich, Lyon, Benichou, Annie-Claude, Craig, Adam

“…Purpose Omacetaxine mepesuccinate is a first-in-class cephalotaxine demonstrating clinical activity in chronic myeloid leukemia. A subcutaneous (SC)…”
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Protein Kinase C βII Plays an Essential Role in Dendritic Cell Differentiation and Autoregulates Its Own Expression by Pedro J. Cejas, Louise M. Carlson, Jian Zhang, Swami Padmanabhan, Despina Kolonias, Inna Lindner, Stephen Haley, Lawrence H. Boise, Kelvin P. Lee

“…Dendritic cells (DC) arise from a diverse group of hematopoietic progenitors and have marked phenotypic and functional heterogeneity. The signal transduction…”
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Protein kinase C betaII plays an essential role in dendritic cell differentiation and autoregulates its own expression by Cejas, Pedro J, Carlson, Louise M, Zhang, Jian, Padmanabhan, Swami, Kolonias, Despina, Lindner, Inna, Haley, Stephen, Boise, Lawrence H, Lee, Kelvin P

“…Dendritic cells (DC) arise from a diverse group of hematopoietic progenitors and have marked phenotypic and functional heterogeneity. The signal transduction…”
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Bridging the gap in hematological malignancies by Parmar, Simrit, Iyer, Swami Padmanabhan

“…After the success of the BTG Series in Singapore in 2010 and 2011, meeting organizers held the 3rd International Hematologic Malignancies Conference in Hong…”
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Ofatumumab, a Novel CD20 Monoclonal Antibody, Is Active in Patients With Fludarabine- and Alemtuzumab-Refractory or Bulky Fludarabine-Refractory Chronic Lymphocytic Leukemia Irrespective of Prior Rituximab by Wierda, William, Kipps, Thomas, Mayer, Jiří, Stilgenbauer, Stephan, Williams, Cathy D., Hellmann, Andrzej, Robak, Tadeusz, Furman, Richard R., Hillmen, Peter, Trneny, Marek, Dyer, Martin J.S., Padmanabhan, Swami, Piotrowska, Magdalena, Kozak, Tomas, Chan, Geoffrey, Davis, Randy, Losic, Nedjad, Wilms, Joris, Russell, Charlotte, Österborg, Anders

“…Ofatumumab, a novel CD20 monoclonal antibody, produces high response rates regardless of prior rituximab exposure in patients with fludarabine- and…”
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Aggressive relapse of multiple myeloma with intracerebral extension and associated hemorrhage by Reddy, Nishitha, Karampelas, Ioannis, Chanan-Khan, Asher, Fenstermaker, Robert, Padmanabhan, Swami

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