Search Results - "Padmakumar, V C"

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration by Diril, M. Kasim, Ratnacaram, Chandrahas Koumar, Padmakumar, V. C, Du, Tiehua, Wasser, Martin, Coppola, Vincenzo, Tessarollo, Lino, Kaldis, Philipp

“…Cyclin-dependent kinase 1 (Cdk1) is an archetypical kinase and a central regulator that drives cells through G2 phase and mitosis. Knockouts of Cdk2, Cdk3,…”
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Loss of Cdk2 and Cyclin A2 Impairs Cell Proliferation and Tumorigenesis by GOPINATHAN, Lakshmi, SHAWN LU WEN TAN, PADMAKUMAR, V. C, COPPOLA, Vincenzo, TESSAROLLO, Lino, KALDIS, Philipp

“…Cell-cycle inhibition has yet to offer a generally effective approach to cancer treatment, but a full evaluation of different combinations of cell-cycle…”
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Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin by Lüke, Yvonne, Zaim, Hafida, Karakesisoglou, Iakowos, Jaeger, Verena M, Sellin, Lorenz, Lu, Wenshu, Schneider, Maria, Neumann, Sascha, Beijer, Asa, Munck, Martina, Padmakumar, V.C, Gloy, Joachim, Walz, Gerd, Noegel, Angelika A

“…Giant isoforms, encoded by Nesprin-1 (Syne1) and Nesprin-2 (Syne2), are multifunctional actin-binding and nuclear-envelope-associated proteins belonging to the…”
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Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation by Malik, Mariam, Jividen, Kasey, Padmakumar, V. C, Cataisson, Christophe, Li, Luowei, Lee, Jessica, Howard, O. M. Zack, Yuspa, Stuart H

“…Nuclear translocation of cytosolic CLIC4 is an essential feature of its proapoptotic and prodifferentiation functions. Here we demonstrate that CLIC4 is…”
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Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope by Libotte, Thorsten, Zaim, Hafida, Abraham, Sabu, Padmakumar, V C, Schneider, Maria, Lu, Wenshu, Munck, Martina, Hutchison, Christopher, Wehnert, Manfred, Fahrenkrog, Birthe, Sauder, Ursula, Aebi, Ueli, Noegel, Angelika A, Karakesisoglou, Iakowos

“…The vertebrate proteins Nesprin-1 and Nesprin-2 (also referred to as Enaptin and NUANCE) together with ANC-1 of Caenorhabditis elegans and MSP-300 of…”
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CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma by Shukla, A, Edwards, R, Yang, Y, Hahn, A, Folkers, K, Ding, J, Padmakumar, V C, Cataisson, C, Suh, K S, Yuspa, S H

“…Cancer stroma has a profound influence on tumor development and progression. The conversion of fibroblasts to activated myofibroblasts is a hallmark of…”
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inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope by Padmakumar, V.C, Libotte, Thorsten, Lu, Wenshu, Zaim, Hafida, Abraham, Sabu, Noegel, Angelika A, Gotzmann, Josef, Foisner, Roland, Karakesisoglou, Iakowos

“…Nesprins form a novel class of nuclear envelope-anchored spectrin-repeat proteins. We show that a direct association of their highly conserved C-terminal…”
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Cdk2 and Cdk4 Activities Are Dispensable for Tumorigenesis Caused by the Loss of p53 by Padmakumar, V. C., Aleem, Eiman, Berthet, Cyril, Hilton, Mary Beth, Kaldis, Philipp

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton by Padmakumar, V.C, Abraham, Sabu, Braune, Stephan, Noegel, Angelika A, Tunggal, Budi, Karakesisoglou, Iakowos, Korenbaum, Elena

“…Enaptin belongs to a family of recently identified giant proteins that associate with the F-actin cytoskeleton as well as the nuclear membrane. It is composed…”
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Spontaneous skin erosions and reduced skin and corneal wound healing characterize CLIC4(NULL) mice by Padmakumar, V C, Speer, Kelsey, Pal-Ghosh, Sonali, Masiuk, Katelyn E, Ryscavage, Andrew, Dengler, Samuel L, Hwang, Shelly, Edwards, John C, Coppola, Vincenzo, Tessarollo, Lino, Stepp, Mary Ann, Yuspa, Stuart H

“…Cutaneous wound healing is a complex process involving blood clotting, inflammation, migration of keratinocytes, angiogenesis, and, ultimately, tissue…”
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A gradient PCR-based screen for use in site-directed mutagenesis by Padmakumar, V.C, Varadarajan, Raghavan

“…Site-directed mutagenesis is widely used to study protein and nucleic acid structure and function. Despite recent advancements in the efficiency of procedures…”
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CLIC4 regulates TGF-[beta]-dependent myofibroblast differentiation to produce a cancer stroma by Shukla, A, Edwards, R, Yang, Y, Hahn, A, Folkers, K, Ding, J, Padmakumar, V C, Cataisson, C, Suh, K S, Yuspa, S H

“…Cancer stroma has a profound influence on tumor development and progression. The conversion of fibroblasts to activated myofibroblasts is a hallmark of…”
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Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line by Padmakumar, Vc, Masiuk, Katelyn E, Luger, Dror, Lee, Christina, Coppola, Vincenzo, Tessarollo, Lino, Hoover, Shelley B, Karavanova, Irina, Buonanno, Andres, Simpson, R Mark, Yuspa, Stuart H

“…Chloride Intracellular Channel 4 (CLIC4) is one of seven members in the closely related CLIC protein family. CLIC4 is involved in multiple cellular processes…”
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Spontaneous Skin Erosions and Reduced Skin and Corneal Wound Healing Characterize CLIC4NULL Mice by Padmakumar, V.C, Speer, Kelsey, Pal-Ghosh, Sonali, Masiuk, Katelyn E, Ryscavage, Andrew, Dengler, Samuel L, Hwang, Shelly, Edwards, John C, Coppola, Vincenzo, Tessarollo, Lino, Stepp, Mary Ann, Yuspa, Stuart H

“…Cutaneous wound healing is a complex process involving blood clotting, inflammation, migration of keratinocytes, angiogenesis, and, ultimately, tissue…”
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Abstract 1418: CLIC4 regulates carcinogenesis in a TGF-β context-dependent manner by Shukla, Anjali, Edwards, Rebecca, Yang, Yihan, Hahn, Alexandra, Padmakumar, VC, Ryscavage, Andrew, Suh, Kwang S., Yuspa, Stuart H.

“…Abstract CLIC4 is a 28kD, ubiquitously expressed, redox-regulated, multifunctional protein. It is dimorphic and can transition between membrane bound or…”
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S 3-33: Lamin A/C dependent localization of nuance, a giant actin binding protein of the nuclear envelope by Libotte, Thorsten, Zaim, Hafida, Sabu Abraham, Padmakumar, V C

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S 3-30: Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton by Padmakumar, V C, Sabu Abraham, Braune, Stephan, Noegel, Angelika A

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