Search Results - "Padmaja, Divya"

Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis by Pratheeshkumar, Poyil, Son, Young-Ok, Budhraja, Amit, Wang, Xin, Ding, Songze, Wang, Lei, Hitron, Andrew, Lee, Jeong-Chae, Kim, Donghern, Divya, Sasidharan Padmaja, Chen, Gang, Zhang, Zhuo, Luo, Jia, Shi, Xianglin

“…Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and metastasis. Luteolin is a common…”
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Telomerase reverse transcriptase mutations are independent predictor of disease‐free survival in Middle Eastern papillary thyroid cancer by Bu, Rong, Siraj, Abdul K., Divya, Sasidharan Padmaja, Kong, Yan, Parvathareddy, Sandeep Kumar, Al‐Rasheed, Maha, Al‐Obaisi, Khadija A.S., Victoria, Ingrid G., Al‐Sobhi, Saif S., Al‐Dawish, Mohammed, Al‐Dayel, Fouad, Al‐Kuraya, Khawla S.

“…Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Tumor recurrence occurs in ∼20% of PTCs and some reach advanced stages. Promoter…”
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APC truncating mutations in Middle Eastern Population: Tankyrase inhibitor is an effective strategy to sensitize APC mutant CRC To 5-FU chemotherapy by Siraj, Abdul K., Kumar Parvathareddy, Sandeep, Pratheeshkumar, Poyil, Padmaja Divya, Sasidharan, Ahmed, Saeeda Omer, Melosantos, Roxanne, Begum, Rafia, Concepcion, Rica Micaela J.A., Al-Sanea, Nasser, Ashari, Luai H, Abduljabbar, Alaa, Al-Dayel, Fouad, Al-Kuraya, Khawla S.

“…[Display omitted] •In Saudi Arabia, CRC is the second most common cancer.•In our cohort, APC mutation was independent predictor of superior overall…”
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PLK1 and PARP positively correlate in Middle Eastern breast cancer and their combined inhibition overcomes PARP inhibitor resistance in triple negative breast cancer by Siraj, Abdul K, Poyil, Pratheesh Kumar, Padmaja, Divya, Parvathareddy, Sandeep Kumar, Alobaisi, Khadija, Thangavel, Saravanan, Diaz, Roxanne, Begum, Rafia, Almalik, Osama, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Despite advancements in treatment approaches, patients diagnosed with aggressive breast cancer (BC) subtypes typically face an unfavorable prognosis. Globally,…”
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PLK1 and FoxM1 expressions positively correlate in papillary thyroid carcinoma and their combined inhibition results in synergistic anti‐tumor effects by Poyil, Pratheesh Kumar, Siraj, Abdul K., Padmaja, Divya, Parvathareddy, Sandeep Kumar, Thangavel, Saravanan, Alobaisi, Khadija, Diaz, Roxanne, Begum, Rafia, Haqawi, Wael, Al‐Sobhi, Saif S., Al‐Dayel, Fouad, Al‐Kuraya, Khawla S.

“…Polo‐like kinase 1 (PLK1; also known as serine/threonine‐protein kinase PLK1) serves as a central player in cell proliferation, exerting critical regulatory…”
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Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling by Poyil, Pratheesh Kumar, Siraj, Abdul K., Padmaja, Divya, Parvathareddy, Sandeep Kumar, Diaz, Roxanne, Thangavel, Saravanan, Begum, Rafia, Haqawi, Wael, Al‐Mohanna, Falah Hassan, Al‐Sobhi, Saif S., Al‐Dayel, Fouad, Al‐Kuraya, Khawla S.

“…Furin belongs to the pro‐protein convertases (PCs) family and its aberrant expression has been documented in various types of cancers; however, its role in…”
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Polo-like Kinase 1 Predicts Lymph Node Metastasis in Middle Eastern Colorectal Cancer Patients; Its Inhibition Reverses 5-Fu Resistance in Colorectal Cancer Cells by Poyil, Pratheesh Kumar, Siraj, Abdul K, Padmaja, Divya, Parvathareddy, Sandeep Kumar, Alobaisi, Khadija, Thangavel, Saravanan, Begum, Rafia, Diaz, Roxanne, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Polo-like kinase 1 (PLK1) is a serine/threonine-protein kinase essential for regulating multiple stages of cell cycle progression in mammals. Aberrant…”
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RETRACTED ARTICLE: Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism by Pratheeshkumar, Poyil, Son, Young-Ok, Divya, Sasidharan Padmaja, Wang, Lei, Zhang, Zhuo, Shi, Xianglin

“…Arsenic is a well-documented human carcinogen. The present study explored the role of the onco-miR, miR-21 and its target protein, programmed cell death 4…”
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Arsenic Induces Insulin Resistance in Mouse Adipocytes and Myotubes Via Oxidative Stress-Regulated Mitochondrial Sirt3-FOXO3a Signaling Pathway by Padmaja Divya, Sasidharan, Pratheeshkumar, Poyil, Son, Young-Ok, Vinod Roy, Ram, Andrew Hitron, John, Kim, Donghern, Dai, Jin, Wang, Lei, Asha, Padmaja, Huang, Bin, Xu, Mei, Luo, Jia, Zhang, Zhuo

“…Chronic exposure to arsenic via drinking water is associated with an increased risk for development of type 2 diabetes mellitus (T2DM). This study investigates…”
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Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells by Son, Young-Ok, Pratheeshkumar, Poyil, Divya, Sasidharan Padmaja, Zhang, Zhuo, Shi, Xianglin

“…Nickel-containing compounds are widely used in industry. Nickel is a known human carcinogen that primarily affects the lungs. Proposed mechanisms of…”
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Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways by Pratheeshkumar, Poyil, Son, Young-Ok, Divya, Sasidharan Padmaja, Roy, Ram Vinod, Hitron, John Andrew, Wang, Lei, Kim, Donghern, Dai, Jin, Asha, Padmaja, Zhang, Zhuo, Wang, Yitao, Shi, Xianglin

“…Hexavalent chromium [Cr(VI)] is a well-known human carcinogen associated with the incidence of lung cancer. Inhibition of metal induced carcinogenesis by a…”
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Retraction Note: Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism by Pratheeshkumar, Poyil, Son, Young-Ok, Divya, Sasidharan Padmaja, Wang, Lei, Zhang, Zhuo, Shi, Xianglin

“…This article has been retracted…”
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CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells by Pratheeshkumar, Poyil, Siraj, Abdul K, Divya, Sasidharan Padmaja, Parvathareddy, Sandeep Kumar, Alobaisi, Khadija, Al-Sobhi, Saif S, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Chromodomain-helicase-DNA-binding protein 4 (CHD4), a core subunit of the nucleosome remodeling and deacetylation (NuRD) complex is highly expressed in several…”
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Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced Carcinogenesis by Son, Young-Ok, Pratheeshkumar, Poyil, Roy, Ram Vinod, Hitron, John Andrew, Wang, Lei, Divya, Sasidharan Padmaja, Xu, Mei, Luo, Jia, Chen, Gang, Zhang, Zhuo, Shi, Xianglin

“…Arsenic (As3+) is a carcinogen with considerable environmental and occupational relevancy. The present study shows that As3+-transformed human lung bronchial…”
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Downregulation of SKP2 in Papillary Thyroid Cancer Acts Synergistically With TRAIL on Inducing Apoptosis via ROS by Pratheeshkumar, Poyil, Siraj, Abdul K, Divya, Sasidharan Padmaja, Parvathareddy, Sandeep Kumar, Begum, Rafia, Melosantos, Roxanne, Al-Sobhi, Saif S, Al-Dawish, Mohammed, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Abstract Context and Objective S-phase kinase protein 2 (SKP2) is an F-box protein with proteasomal properties and has been found to be overexpressed in a…”
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Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling by Pratheeshkumar, Poyil, Son, Young-Ok, Divya, Sasidharan Padmaja, Turcios, Lilia, Roy, Ram Vinod, Hitron, John Andrew, Wang, Lei, Kim, Donghern, Dai, Jin, Asha, Padmaja, Zhang, Zhuo, Shi, Xianglin

“…Hexavalent chromium [Cr(VI)] is a well-known human carcinogen associated with an increased risk of lung cancer. However, the mechanisms underlying…”
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Krupple-Like Factor 5 is a Potential Therapeutic Target and Prognostic Marker in Epithelial Ovarian Cancer by Siraj, Abdul K, Pratheeshkumar, Poyil, Divya, Sasidharan Padmaja, Parvathareddy, Sandeep Kumar, Alobaisi, Khadija A, Thangavel, Saravanan, Siraj, Sarah, Al-Badawi, Ismail A, Al-Dayel, Fouad, Al-Kuraya, Khawla S

“…Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. Despite current therapeutic and surgical options, advanced EOC shows poor…”
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Epigenetic targets of arsenic: emphasis on epigenetic modifications during carcinogenesis by Roy, Ram Vinod, Son, Young-Ok, Pratheeshkumar, Poyil, Wang, Lei, Hitron, John Andrew, Divya, Sasidharan Padmaja, D, Rakesh, Kim, Donghern, Yin, Yuanqin, Zhang, Zhuo, Shi, Xianglin

“…DNA methylation and histone modification promote opening and closure of chromatin structure, which affects gene expression without altering the DNA sequence…”
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Abstract 2933: KLF5 and its association with HIF-1α promotes PTC progression and metastatic potential through AKT activation by Poyil, Pratheeshkumar, Siraj, Abdul K, Padmaja, Divya, Parvathareddy, Sandeep Kumar, Thangavel, Saravanan, Melosantos, Roxanne, Victoria, Ingrid G., Begum, Rafia, Al-Dayel, Fouad, Al-Kuraya, Khawla S.

“…Thyroid cancer is the second most common malignancy among females in Saudi Arabia, with Papillary thyroid carcinoma (PTC) accounting for 80-90%. Kruppel-like…”
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Abstract 3447: APC truncating mutations in Middle Eastern population: Tankyrase inhibitor is an effective strategy to sensitize APC mutant CRC to 5-FU chemotherapy by Parvathareddy, Sandeep K., Siraj, Abdul K., Bu, Rong, Poyil, Prateeshkumar, Masoodi, Tariq, Padmaja, Divya Sasidharan, Concepcion, Rica, Begum, Rafia, Sabido, Maria A., Melosantos, Roxanne, Al-Sanea, Nasser, Al-Dayel, Fouad, Al-Kuraya, Khawla S.

“…Colorectal Cancer (CRC) is the leading cause of cancer related death and the most common cancer affecting Saudi males. Mutation of the adenomatous polyposis…”
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