Search Results - "Padley, Douglas J"

Platelet lysate consisting of a natural repair proteome supports human mesenchymal stem cell proliferation and chromosomal stability by Crespo-Diaz, Ruben, Behfar, Atta, Butler, Greg W, Padley, Douglas J, Sarr, Michael G, Bartunek, Jozef, Dietz, Allan B, Terzic, Andre

“…With favorable regenerative and immunotolerant profiles, patient-derived human mesenchymal stem cells (hMSCs) are increasingly considered in cell therapy…”
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Sterility testing of hematopoietic progenitor cell products: a single-institution series of culture-positive rates and successful infusion of culture-positive products by Padley, Douglas J., Dietz, Allan B., Gastineau, Dennis A.

“…BACKGROUND: Administration of culture‐positive hematopoietic progenitor cells (HPCs) causing adverse events has been a hypothesized yet largely unmeasured risk…”
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Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma by Markovic, Svetomir N, Dietz, Allan B, Greiner, Carl W, Maas, Mary L, Butler, Greg W, Padley, Douglas J, Bulur, Peggy A, Allred, Jacob B, Creagan, Edward T, Ingle, James N, Gastineau, Dennis A, Vuk-Pavlovic, Stanimir

“…Dendritic cells (DCs) have been used as vaccines in clinical trials of immunotherapy of cancer and other diseases. Nonetheless, progress towards the use of DCs…”
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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting Phase I human trials by Chen, Bingkun K., Staff, Nathan P., Knight, Andrew M., Nesbitt, Jarred J., Butler, Greg W., Padley, Douglas J., Parisi, Joseph E., Dietz, Allan B., Windebank, Anthony J.

“…Background There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative…”
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Discordant CD34+ cell results in peripheral blood and hematopoietic progenitor cell-apheresis product: implications for clinical decisions and impact on patient treatment by Liwski, Courtney J., Padley, Douglas J., Gustafson, Michael P., Winters, Jeffrey L., Gastineau, Dennis A., Jacob, Eapen K.

“…Case Report A 50‐year‐old male with T‐cell lymphoma presented for autologous peripheral blood stem cell transplantation. After granulocyte–colony‐stimulating…”
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Folate Receptor Alpha Peptide Vaccine Generates Immunity in Breast and Ovarian Cancer Patients by Kalli, Kimberly R, Block, Matthew S, Kasi, Pashtoon M, Erskine, Courtney L, Hobday, Timothy J, Dietz, Allan, Padley, Douglas, Gustafson, Michael P, Shreeder, Barath, Puglisi-Knutson, Danell, Visscher, Dan W, Mangskau, Toni K, Wilson, Glynn, Knutson, Keith L

“…Folate receptor alpha (FR) is overexpressed in several cancers. Endogenous immunity to the FR has been demonstrated in patients and suggests the feasibility of…”
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Rapid generation of sustainable HER2-specific T cell immunity in HER2 breast cancer patients using a degenerate HLA class II epitope vaccine by Knutson, Keith L., Block, Matthew S., Norton, Nadine, Erskine, Courtney L., Hobday, Timothy J., Dietz, Allan B., Padley, Douglas J., Gustafson, Michael P., Puglisi-Knutson, Danell J., Mangskau, Toni K., Chumsri, Saranya, Dueck, Amylou C., Karyampudi, Lavakumar, Wilson, Glynn, Degnim, Amy

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A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting P hase I human trials by Chen, Bingkun K., Staff, Nathan P., Knight, Andrew M., Nesbitt, Jarred J., Butler, Greg W., Padley, Douglas J., Parisi, Joseph E., Dietz, Allan B., Windebank, Anthony J.

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Discordant CD 34+ cell results in peripheral blood and hematopoietic progenitor cell–apheresis product: implications for clinical decisions and impact on patient treatment by Liwski, Courtney J., Padley, Douglas J., Gustafson, Michael P., Winters, Jeffrey L., Gastineau, Dennis A., Jacob, Eapen K.

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Abstract A82: Metronomic cyclophosphamide followed by a multi-peptide folate receptor vaccine for ovarian and breast cancer immunotherapy in the setting of minimal residual disease - a feasibility study by Kalli, Kimberly R., Erskine, Courtney L., Krempski, James W., Benson, Linda M., Suman, Vera J., Padley, Douglas J., Dietz, Allan B., Hobday, Timothy J., Degnim, Amy C., Hartmann, Lynn C., Block, Matthew S., Knutson, Keith L.

“…Background: Current options to prevent ovarian and breast cancer recurrence are limited. However, signs of anti-tumor immunity are associated with improved…”
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Safety and Feasibility for Pediatric Cardiac Regeneration Using Epicardial Delivery of Autologous Umbilical Cord Blood‐Derived Mononuclear Cells Established in a Porcine Model System by Cantero Peral, Susana, Burkhart, Harold M., Oommen, Saji, Yamada, Satsuki, Nyberg, Scott L., Li, Xing, O'Leary, Patrick W., Terzic, Andre, Cannon, Bryan C., Nelson, Timothy J.

“…This study established a porcine pipeline to evaluate the feasibility and long‐term safety of autologous umbilical cord blood mononuclear cells (UCB‐MNCs)…”
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Priming Tissue-specific Cellular Immunity in a Phase I Trial of Autologous Dendritic Cells for Prostate Cancer by Burch, P A, Breen, J K, Buckner, J C, Gastineau, D A, Kaur, J A, Laus, R L, Padley, D J, Peshwa, M V, Pitot, H C, Richardson, R L, Smits, B J, Sopapan, P, Strang, G, Valone, F H, Vuk-Pavlović, S

“…We attempted to induce therapeutic immunity against prostate-derived tissues in patients suffering from progressive hormone-refractory metastatic prostate…”
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Factors Contributing to Renal Failure in Patients Undergoing Stem Cell Transplant for Multiple Myeloma and Amyloidosis by Richa, Elie M., Winters, Jeffrey L., Padley, Douglas J., Stowers, Robert E., Bryant, Sandra C., Ege, Hilmi, Gastineau, Dennis A.

“…Autologous stem cells transplant in tandem is considered the standard therapy for patients with Multiple Myeloma (MM) and Primary Amyloidosis. The collection…”
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AMD3100 Affects Autograft Lymphocyte Collection and Progression-Free Survival After Autologous Stem Cell Transplantion in Non-Hodgkin Lymphoma by Holtan, Shernan G., Porrata, Luis F., Micallef, Ivana N.M., Padley, Douglas J., Inwards, David J., Ansell, Stephen A., Johnston, Patrick B., Gastineau, Dennis A., Markovic, Svetomir N.

“…Autograft absolute lymphocyte count (A-ALC) affects survival after autologous stem cell transplantation (ASCT) in non- Hodgkin lymphoma (NHL). AMD3100, a CXCR4…”
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Effect of AMD3100 on T Lymphocyte Subpopulations in Apheresis Products of Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation for Non Hodgkin Lymphoma by Holtan, Shernan G., Porrata, Luis F., Inwards, David J., Ansell, Stephen A., Padley, Douglas J., Micallef, Ivana N., Litzow, Mark R., Johnston, Patrick B., Hayman, Suzanne R., Kumar, Shaji K., Gertz, Morie A., Lacy, Martha Q., Dispenzieri, Angela, Gastineau, Dennis A., Teferi, Ayalew, Elliot, Michelle, Hogan, William J., Markovic, Svetomir N.

“…AMD3100, a CXCR4 receptor antagonist, has been studied as a stem cell mobilization agent for the purpose of autologous stem cell transplantation (ASCT) in…”
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Increasing the Number of Apheresis Collections Increases Lymphocyte Collection and Affects Survival after Autologous Stem Cell Transplantation for Non-Hodgkin Lymphoma by Porrata, Luis F., Gastineau, Dennis A., Pineda, Alvaro, Winters, Jeffrey L., Moore, S. Breanndan, Padley, Douglas J., Bundy, Kevin L., Litzow, Mark R., Micallef, Ivana N.M., Inwards, David J., Ansell, Stephen M., Gertz, Morie A., Lacy, Martha Q., Dispenzieri, Angela, Tefferi, Ayalew, Elliott, Michelle, Hogan, William J., Hayman, Suzanne R., Markovic, Svetomir N.

“…Peripheral blood infused total autograft absolute lymphocyte count (A-ALC) correlates with day 15 absolute lymphocyte count and is an independent prognostic…”
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AMD3100 affects autograft lymphocyte collection and progression-free survival after autologous stem cell transplantation in non-Hodgkin lymphoma by Holtan, Shernan G, Porrata, Luis F, Micallef, Ivana N M, Padley, Douglas J, Inwards, David J, Ansell, Stephen A, Johnston, Patrick B, Gastineau, Dennis A, Markovic, Svetomir N

“…Autograft absolute lymphocyte count (A-ALC) affects survival after autologous stem cell transplantation (ASCT) in non- Hodgkin lymphoma (NHL). AMD3100, a CXCR4…”
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Mature myeloid dendritic cells for clinical use prepared from CD14+ cells isolated by immunomagnetic adsorption by Padley, D J, Dietz, A B, Gastineau, D A, Vuk-Pavlovic, S

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