Search Results - "Padilla, Karen M"

Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels by McCormack, Ken, Santos, Sonia, Chapman, Mark L, Krafte, Douglas S, Marron, Brian E, West, Christopher W, Krambis, Michael J, Antonio, Brett M, Zellmer, Shannon G, Printzenhoff, David, Padilla, Karen M, Lin, Zhixin, Wagoner, P Kay, Swain, Nigel A, Stupple, Paul A, de Groot, Marcel, Butt, Richard P, Castle, Neil A

“…Voltage-gated sodium (Na ᵥ) channels play a fundamental role in the generation and propagation of electrical impulses in excitable cells. Here we describe two…”
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TRPA1 ankyrin repeat six interacts with a small molecule inhibitor chemotype by Tseng, Wei Chou, Pryde, David C., Yoger, Katrina E., Padilla, Karen M., Antonio, Brett M., Han, Seungil, Shanmugasundaram, Veerabahu, Gerlach, Aaron C.

“…TRPA1, a member of the transient receptor potential channel (TRP) family, is genetically linked to pain in humans, and small molecule inhibitors are…”
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A comprehensive approach to identifying repurposed drugs to treat SCN8A epilepsy by Atkin, Talia A., Maher, Chani M., Gerlach, Aaron C., Gay, Bryant C., Antonio, Brett M., Santos, Sonia C., Padilla, Karen M., Rader, JulieAnn, Krafte, Douglas S., Fox, Matthew A., Stewart, Gregory R., Petrovski, Slavé, Devinsky, Orrin, Might, Matthew, Petrou, Steven, Goldstein, David B.

“…Summary Objective Many previous studies of drug repurposing have relied on literature review followed by evaluation of a limited number of candidate compounds…”
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Estrogen Receptor (ER) Modulators Each Induce Distinct Conformational Changes in ER α and ER β by Paige, Lisa A., Christensen, Dale J., Grøn, Hanne, Norris, John D., Gottlin, Elizabeth B., Padilla, Karen M., Chang, Ching-yi, Ballas, Lawrence M., Hamilton, Paul T., McDonnell, Donald P., Fowlkes, Dana M.

“…Estrogen receptor (ER) modulators produce distinct tissue-specific biological effects, but within the confines of the established models of ER action it is…”
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Enhanced Dendritic Cell Antigen Presentation in RNA-Based Immunotherapy by Kalady, Matthew F., Onaitis, Mark W., Padilla, Karen M., Emani, Sirisha, Tyler, Douglas S., Pruitt, Scott K.

“…Background. Dendritic cells pulsed with mRNA provide a unique approach to tumor immunotherapy. We hypothesized that increased mRNA transfection efficiency and…”
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Autoantibodies to Type VII Collagen Recognize Epitopes in a Fibronectin-Like Region of the Noncollagenous (NC1) Domain by Gammon, W Ray, Murrell, Dédée F., Jenison, Mark W., Padilla, Karen M., Prisayanh, Phillip S., Jones, Drew A., Briggaman, Robert A., Hunt, Stephen W.

“…Autoantibodies to type VII collagen are characteristic of the blistering diseases epidermolysis bullosa acquisita and bullous systemic lupus erythematosus…”
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A comprehensive approach to identifying repurposed drugs to treat SCN 8A epilepsy by Atkin, Talia A., Maher, Chani M., Gerlach, Aaron C., Gay, Bryant C., Antonio, Brett M., Santos, Sonia C., Padilla, Karen M., Rader, JulieAnn, Krafte, Douglas S., Fox, Matthew A., Stewart, Gregory R., Petrovski, Slavé, Devinsky, Orrin, Might, Matthew, Petrou, Steven, Goldstein, David B.

“…Summary Objective Many previous studies of drug repurposing have relied on literature review followed by evaluation of a limited number of candidate compounds…”
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Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels by McCormack, Ken, Santos, Sonia, Chapman, Mark L., Krafte, Douglas S., Marron, Brian E., West, Christopher W., Krambis, Michael J., Antonio, Brett M., Zellmer, Shannon G., Printzenhoff, David, Padilla, Karen M., Lin, Zhixin, Wagoner, P. Kay, Swain, Nigel A., Stupple, Paul A., de Groot, Marcel, Butt, Richard P., Castle, Neil A.

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Noncollagenous (NC1) Domain of Collagen VII Resembles Multidomain Adhesion Proteins Involved in Tissue-Specific Organization of Extracellular Matrix by Gammon, W. Ray, Abernethy, M. Lisa, Padilla, Karen M., Prisayanh, Phillip S., Cook, Molly E., Wright, Jocyndra, Briggaman, Robert A., Hunt, Stephen W.

“…Type VII collagen (C7) is a stratified squamous epithelial basement membrane protein composed of three identical alpha chains, each consisting of a 145-kDa…”
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