Search Results - "Padilha, Alessandra S."

The Role of Antioxidants in the Prevention of Cadmium-Induced Endothelial Dysfunction by Almenara, Camila Cruz Pereira, Oliveira, Thiago F, Padilha, Alessandra S

“…Cadmium is a worldwide spread toxicant that accumulates in tissues and affects many organs, mainly through oxidative damage. Oxidative stress is often…”
Get more information

Chronic cadmium treatment promotes oxidative stress and endothelial damage in isolated rat aorta by Almenara, Camila C P, Broseghini-Filho, Gilson B, Vescovi, Marcus V A, Angeli, Jhuli K, Faria, Thaís de O, Stefanon, Ivanita, Vassallo, Dalton V, Padilha, Alessandra S

“…Cadmium is a highly toxic metal that is present in phosphate fertilizers, and the incidence of cadmium poisoning in the general population has increased,…”
Get full text

Low-level lead exposure increases systolic arterial pressure and endothelium-derived vasodilator factors in rat aortas by Fiorim, Jonaina, Ribeiro Júnior, Rogério F, Silveira, Edna A, Padilha, Alessandra S, Vescovi, Marcos Vinícius A, de Jesus, Honério C, Stefanon, Ivanita, Salaices, Mercedes, Vassallo, Dalton V

“…Chronic lead exposure induces hypertension and alters endothelial function. However, treatment with low lead concentrations was not yet explored. We analyzed…”
Get full text

Acute lead exposure increases arterial pressure: role of the renin-angiotensin system by Simões, Maylla Ronacher, Ribeiro Júnior, Rogério F, Vescovi, Marcos Vinícius A, de Jesus, Honério C, Padilha, Alessandra S, Stefanon, Ivanita, Vassallo, Dalton V, Salaices, Mercedes, Fioresi, Mirian

“…Chronic lead exposure causes hypertension and cardiovascular disease. Our purpose was to evaluate the effects of acute exposure to lead on arterial pressure…”
Get full text

Exposure to a Low Lead Concentration Impairs Contractile Machinery in Rat Cardiac Muscle by Silva, Marito A. S. C, de Oliveira, Thiago F, Almenara, Camila C. P, Broseghini-Filho, Gilson B, Vassallo, Dalton V, Padilha, Alessandra S, Silveira, Edna A

“…Lead exposure has been considered to be a risk factor for hypertension and cardiovascular disease. Our purpose was to evaluate the effects of low plasma lead…”
Get full text

Blood Pressure Decreases Following Lead Treatment Cessation: Highest NO Bioavailability Involved by Broseghini-Filho, Gilson B., Almenara, Camila C. Pereira, Vassallo, Dalton V., Padilha, Alessandra S.

“…Although lead is known to induce arterial hypertension and vascular damage, it is not clear if after cessation of lead treatment, the increase of blood…”
Get full text

Post-weaning protein malnutrition increases blood pressure and induces endothelial dysfunctions in rats by de Belchior, Aucelia C S, Angeli, Jhuli K, Faria, Thaís de O, Siman, Fabiana D M, Silveira, Edna A, Meira, Eduardo F, da Costa, Carlos P, Vassallo, Dalton V, Padilha, Alessandra S

“…Malnutrition during critical periods in early life may increase the subsequent risk of hypertension and metabolic diseases in adulthood, but the underlying…”
Get full text

Subacute cadmium exposure disrupts the hypothalamic-pituitary-gonadal axis, leading to polycystic ovarian syndrome and premature ovarian failure features in female rats by da Costa, Charles S., Oliveira, Thiago F., Freitas-Lima, Leandro C., Padilha, Alessandra S., Krause, Maiara, Carneiro, Maria Tereza W.D., Salgado, Breno S., Graceli, Jones B.

“…Cadmium (Cd), a toxic heavy metal, is a known endocrine disruptor that is associated with reproductive complications. However, few studies have explored the…”
Get full text

Activation of BKCa channels by nitric oxide prevents coronary artery endothelial dysfunction in ouabain-induced hypertensive rats by BRIONES, Ana M, PADILHA, Alessandra S, COGOLLUDO, Angel L, ALONSO, Maria J, VASSALLO, Dalton V, PEREZ-VIZCAINO, Francisco, SALAICES, Mercedes

“…Chronic-ouabain administration to rats induces hypertension and increases the endothelial modulation of vasoconstrictor responses. The aim of this study was to…”
Get full text

Subacute cadmium exposure changes different metabolic functions, leading to type 1 and 2 diabetes mellitus features in female rats by da Costa, Charles S., Oliveira, Thiago F., Dos Santos, Flavia C. F., Padilha, Alessandra S., Krause, Maiara, Carneiro, Maria Tereza W. D., Miranda‐Alves, Leandro, Graceli, Jones B.

“…Cadmium (Cd) is a heavy metal that acts as endocrine disrupting chemical (EDC). Few studies have investigated the effects of Cd exposure on metabolic…”
Get full text

Tension cost correlates with mechanical and biochemical parameters in different myocardial contractility conditions by Moreira, Cleci M., Meira, Eduardo F., Vestena, Luis, Stefanon, Ivanita, Vassallo, Dalton V., Padilha, Alessandra S.

“…Tension cost, the ratio of myosin ATPase activity to tension, reflects the economy of tension development in the myocardium. To evaluate the mechanical…”
Get full text

Maternal protein restriction compromises myocardial contractility in the young adult rat by changing proteins involved in calcium handling by de Belchior, Aucelia C S, Freire, Jr, David D, da Costa, Carlos P, Vassallo, Dalton V, Padilha, Alessandra S, Dos Santos, Leonardo

“…Maternal protein restriction (MPR) during pregnancy is associated with increased cardiovascular risk in the offspring in adulthood. In this study we evaluated…”
Get full text

Preliminary Studies of Acute Cadmium Administration Effects on the Calcium-Activated Potassium (SKCa and BKCa) Channels and Na+/K+-ATPase Activity in Isolated Aortic Rings of Rats by Vassallo, Dalton V., Almenara, Camila C. P., Broseghini-Filho, Gilson Brás, Teixeira, Ariane Calazans, da Silva, David Chaves F., Angeli, Jhuli K., Padilha, Alessandra S.

“…Cadmium is an environmental pollutant closely linked with cardiovascular diseases that seems to involve endothelium dysfunction and reduced nitric oxide (NO)…”
Get full text

In vitro fructose exposure overactivates NADPH oxidase and causes oxidative stress in the isolated rat aorta by Almenara, Camila C.P., Mill, José G., Vassallo, Dalton V., Baldo, Marcelo P., Padilha, Alessandra S.

“…Fructose acutely interferes with cardiovascular function in humans and in animals, but the mechanisms remain unclear. Thus, we tested whether fructose can…”
Get full text

Ouabain Induces Nitric Oxide Release by a PI3K/Akt-dependent Pathway in Isolated Aortic Rings From Rats With Heart Failure by Siman, Fabiana D M, Silveira, Edna A, Fernandes, Aurélia A, Stefanon, Ivanita, Vassallo, Dalton V, Padilha, Alessandra S

“…BACKGROUND:Ouabain occurs in nanomolar concentrations in myocardial infarction and heart failure (HF). However, the effects of ouabain in vascular function in…”
Get full text

Low-dose ouabain administration increases Na⁺,K⁺-ATPase activity and reduces cardiac force development in rats by Meira, Eduardo F, Siman, Fabiana Dayse M, Faria, Thais de O, Júnior, Rogerio F Ribeiro, de Batista, Priscila R, Stefanon, Ivanita, Vassallo, Dalton V, Padilha, Alessandra S

“…Ouabain is a digitalis compound that inhibits the Na(+),K(+)-ATPase (NKA) activity inducing increment in cardiac force. However, this effect seems to be dose…”
Get more information

Flaxseed oil increases aortic reactivity to phenylephrine through reactive oxygen species and the cyclooxygenase-2 pathway in rats by Nunes, Dieli Oliveira, Almenara, Camila Cruz Pereira, Broseghini-Filho, Gilson Brás, Silva, Marito Afonso Sousa Costa, Stefanon, Ivanita, Vassallo, Dalton V, Padilha, Alessandra S

“…Flaxseed oil has the highest concentration of omega-3 α-linolenic acid, which has been associated with cardiovascular benefit. However, the mechanism…”
Get full text

Acute Cadmium Exposure Reduces the Local Angiotensin I Converting Enzyme Activity and Increases the Tissue Metal Content by Broseghini-Filho, Gilson B, Almenara, Camila C. Pereira, Vescovi, Marcus V. A, Faria, Thaís de O, Vassallo, Dalton V, Angeli, Jhuli K, Padilha, Alessandra S

“…Cadmium exposure causes health problems that may result from increased oxidative stress and from changes in enzyme metalloproteases activities as…”
Get full text

Ouabain treatment changes the role of endothelial factors in rat resistance arteries by Padilha, Alessandra S., Peçanha, Franck M., Vassallo, Dalton V., Alonso, María J., Salaices, Mercedes

“…This study investigates the participation of the endothelial factors in the α-adrenoceptor contractile responses in mesenteric resistance arteries from 15 days…”
Get full text

CHRONIC OUABAIN TREATMENT ENHANCES CARDIAC MYOSIN ATPase ACTIVITY IN RATS by Padilha, Alessandra S, Moreira, Cleci M, Meira, Eduardo F, Siman, Fabiana DM, Stefanon, Ivanita, Vassallo, Dalton V

“…SUMMARY 1 Chronic ouabain administration increases blood pressure and produces a positive inotropic effect. However, the temporal changes capable of affecting…”
Get full text