Search Results - "Padh, Harish"
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Sequencing and comparative genome analysis of three Indians
Published in Mammalian genome (01-10-2021)“…Remarkable advancement in DNA sequencing (NGS) technology has made personal genome analysis feasible and affordable. Here we present the whole genome…”
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Correction to: Sequencing and comparative genome analysis of three Indians
Published in Mammalian genome (01-10-2021)Get full text
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Application of quality by design approach for intranasal delivery of rivastigmine loaded solid lipid nanoparticles: Effect on formulation and characterization parameters
Published in European journal of pharmaceutical sciences (12-10-2015)“…[Display omitted] •Identification of process parameters affecting quality attributes of rivastigmine SLN.•Determination of process parameters by 33 by full…”
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Implications of gene copy-number variation in health and diseases
Published in Journal of human genetics (01-01-2012)“…Inter-individual genomic variations have recently become evident with advances in sequencing techniques and genome-wide array comparative genomic…”
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Production of heterologous proteins in plants: Strategies for optimal expression
Published in Biotechnology advances (01-07-2010)“…Plants are a promising expression system for the production of heterologous proteins, especially therapeutic proteins. Currently the majority of therapeutic…”
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Application of Box-Behnken design for optimization and development of quetiapine fumarate loaded chitosan nanoparticles for brain delivery via intranasal route
Published in International journal of biological macromolecules (01-08-2016)“…[Display omitted] The objective of the present investigation was to optimize and develop quetiapine fumarate (QF) loaded chitosan nanoparticles (QF-NP) by…”
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Andrographolide : A New Plant-Derived Antineoplastic Entity on Horizon
Published in Evidence-based complementary and alternative medicine (01-01-2011)“…Plant-derived natural products occupy an important position in the area of cancer chemotherapy. Molecules such as vincristine, vinblastine, paclitaxel,…”
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EpiMix Based Novel Vaccine Candidate for Shigella: Evidence of Prophylactic Immunity in Balb/c Mice
Published in International journal of peptide research and therapeutics (01-06-2021)“…Multidrug resistant Shigella is one of the leading causes of mortality in children and infants. Availability of vaccine could prevent the Shigella infection…”
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Search for antibacterial and antifungal agents from selected Indian medicinal plants
Published in Journal of ethnopharmacology (19-09-2006)“…A series of 61 Indian medicinal plants belonging to 33 different families used in various infectious disorders, were screened for their antimicrobial…”
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SULT1A1 copy number variation: ethnic distribution analysis in an Indian population
Published in Annals of human biology (01-11-2017)“…Cytosolic sulfotransferases (SULTs) are phase II detoxification enzymes involved in metabolism of numerous xenobiotics, drugs and endogenous compounds…”
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Dual recombinant Lactococcus lactis for enhanced delivery of DNA vaccine reporter plasmid pPERDBY
Published in Microbiology and immunology (01-04-2017)“…ABSTRACT Food grade Lactococcus lactis has been widely used as an antigen and DNA delivery vehicle. We have previously reported the use of non‐invasive L…”
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Thymidylate synthase enhancer region: Novel allele in Indians
Published in Annals of human biology (01-02-2017)“…Thymidylate synthase (TS) is the major target for fluoropyrimidine drugs like 5-Fluorouracil (5-FU). There are polymorphic tandem repeats in the TYMS gene…”
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Plant genomic DNA isolation: An art or a science
Published in Biotechnology journal (01-03-2007)“…Isolating quality DNA from tissues/cells presents a variety of problems in particular when plants are used as the source material. The specific characteristics…”
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Swertiamarin: A lead from Enicostemma littorale Blume. for anti-hyperlipidaemic effect
Published in European journal of pharmacology (01-09-2009)“…We have investigated the hypolipidemic effects of swertiamarin an active lead isolated from a perennial herb Enicostemma littorale Blume. in high cholesterol…”
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Genetic alterations of the PIK3CA oncogene in human oral squamous cell carcinoma in an Indian population
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-11-2015)“…Objective The phosphatidylinositol 3-kinase ( PIK3 ) genes, which code for heterodimeric lipid kinases, consist of a catalytic subunit, p110α (PIK3CA), which…”
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Variants of NAT2 polymorphisms: Intra and inter-ethnic differences
Published in African journal of biotechnology (17-12-2014)“…N-Acetyltransferase 2 (NAT2) gene is known for its polymorphism. The genetic variations leads to the change in the N-acetylation activity and these differences…”
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Simultaneous HPLC–UV determination of rhein and aceclofenac in human plasma
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-04-2009)“…Diacerein and aceclofenac are prescribed for reducing the symptoms associated with osteoarthritis. We present a simple HPLC method with UV detection for…”
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Antihyperlipidaemic activity of swertiamarin, a secoiridoid glycoside in poloxamer-407-induced hyperlipidaemic rats
Published in Journal of natural medicines (01-10-2009)“…We have investigated antihyperlipidaemic effect of swertiamarin (50 mg/kg, oral once) isolated from the perennial herb Enicostemma littorale Blume in poloxamer…”
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LTBP2 and CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy founder population
Published in European journal of human genetics : EJHG (01-03-2011)“…Primary congenital glaucoma (PCG) is a genetically heterogeneous autosomal recessive disorder, which is an important cause of blindness in childhood. The first…”
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Amelioration of STZ-induced type 1 diabetic nephropathy by aqueous extract of Enicostemma littorale Blume and swertiamarin in rats
Published in Molecular and cellular biochemistry (01-07-2010)“…Diabetic nephropathy (DN) is one of the foremost causes of renal failure and a primary cause of diabetes mellitus related death. Previously, we have reported…”
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