Search Results - "Padella, A"
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SETD2 and histone H3 lysine 36 methylation deficiency in advanced systemic mastocytosis
Published in Leukemia (01-01-2018)“…The molecular basis of advanced systemic mastocytosis (SM) is not fully understood and despite novel therapies the prognosis remains dismal. Exome sequencing…”
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2
Fanconi anemia gene variants in therapy-related myeloid neoplasms
Published in Blood cancer journal (New York) (03-07-2015)Get full text
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Chromothripsis in acute myeloid leukemia: Biological features and impact on survival
Published in Leukemia (18-12-2017)“…Chromothripsis is a one-step genome-shattering catastrophe resulting from disruption of one or few chromosomes in multiple fragments and consequent random…”
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PF169 LONG‐TERM INHIBITION OF CHK1/CHK2 KINASES MODIFY ACUTE LYMPHOBLASTIC LEUKEMIA CELL LINE RESPONSE TO DNA DAMAGING AGENTS
Published in HemaSphere (01-06-2019)“…Background: Acute lymphoblastic leukemia (ALL) cells respond to chemotherapy, or more generally to DNA damages, by activating different DNA Damage Response…”
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PS1020 SNP ARRAY REVEALS A NEW DELETION OF JAK2 IN AML PATIENTS
Published in HemaSphere (01-06-2019)“…Background: Acute Myeloid Leukemia (AML) is a disease of the elderly that initiates in a hematopoietic stem cell and is characterized by clonal hematopoiesis…”
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PS976 METABOLIC REPROGRAMMING OF ACUTE MYELOID LEUKEMIA STEM‐ PROGENITOR CELLS AT RELAPSE
Published in HemaSphere (01-06-2019)“…Background: Primary chemo‐refractory disease and relapse are the most important causes of mortality in acute myeloid leukemia (AML) patients (Döhner et al., N…”
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PS931 ADULT TRIPLE NEGATIVE ACUTE LYMPHOBLASTIC LEUKEMIA FUSION DETECTION: CHALLENGING AIM FOR PH‐ ALTERNATIVE THERAPIES
Published in HemaSphere (01-06-2019)“…Background: The adult “triple negative” [Ph‐/‐/‐; neg for t(9;22); t(1;19); t(4;11); 61% of adult B‐ALL (Roberts KG et al., J Clin Oncol. 2017)] B‐ALL group is…”
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PS928 “3C‐UP” A NEW ADULT PHILADELPHIA NEGATIVE ACUTE LYMPHOBLASTIC LEUKEMIA SUBGROUP: NOVEL MOLECULAR MARKERS
Published in HemaSphere (01-06-2019)“…Background: The adult “triple negative” [Ph‐/‐/‐; neg for t(9;22); t(1;19); t(4;11); 61% of adult B‐ALL (Roberts KG et al., JCO. 2017)] B‐ALL group is…”
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PS997 A NEW BIOMARKER OF RESPONSE TO 5‐AZACITIDINE THERAPY IN MDS AND AML PATIENTS: SIRPB1
Published in HemaSphere (01-06-2019)“…Background: Myelodisplastic syndromes (MDS) and Acute Myeloid Leukemia (AML) are a group of diseases of the elderly that initiates in a hematopoietic stem cell…”
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PF197 A NEW CLASSIFICATION OF ACUTE MYELOID LEUKEMIA BASED ON INTEGRATED GENOMICS AND METABOLOMICS
Published in HemaSphere (01-06-2019)“…Background: An expanding body of evidence indicates that targeting cell metabolism is a promising therapeutic strategy in acute myeloid leukemia (AML)…”
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