Search Results - "Padayachy, Laura"

High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing by Macheret, Morgane, Bhowmick, Rahul, Sobkowiak, Katarzyna, Padayachy, Laura, Mailler, Jonathan, Hickson, Ian D., Halazonetis, Thanos D.

“…DNA replication stress, a feature of human cancers, often leads to instability at specific genomic loci, such as the common fragile sites (CFSs). Cells…”
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Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks by Sotiriou, Sotirios K., Kamileri, Irene, Lugli, Natalia, Evangelou, Konstantinos, Da-Ré, Caterina, Huber, Florian, Padayachy, Laura, Tardy, Sebastien, Nicati, Noemie L., Barriot, Samia, Ochs, Fena, Lukas, Claudia, Lukas, Jiri, Gorgoulis, Vassilis G., Scapozza, Leonardo, Halazonetis, Thanos D.

“…Human cancers are characterized by the presence of oncogene-induced DNA replication stress (DRS), making them dependent on repair pathways such as…”
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RECQL4 is not critical for firing of human DNA replication origins by Padayachy, Laura, Ntallis, Sotirios G., Halazonetis, Thanos D.

“…Human RECQL4, a member of the RecQ helicase family, plays a role in maintaining genomic stability, but its precise function remains unclear. The N-terminus of…”
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Loss of histone H3.3 results in DNA replication defects and altered origin dynamics in C. elegans by Strobino, Maude, Wenda, Joanna M, Padayachy, Laura, Steiner, Florian A

“…Histone H3.3 is a replication-independent variant of histone H3 with important roles in development, differentiation, and fertility. Here, we show that loss of…”
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A method to sequence genomic sites of mitotic DNA synthesis in mammalian cells by Mailler, Jonathan, Padayachy, Laura, Halazonetis, Thanos D

“…Under normal conditions, the genome of eukaryotic cells is faithfully replicated during S phase. However, in cells exposed to DNA polymerase inhibitors, some…”
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Annexin V expression on CD4+ T cells with regulatory function by Bollinger, Anna‐Lena, Bollinger, Thomas, Rupp, Jan, Shima, Kensuke, Gross, Natalie, Padayachy, Laura, Chicheportiche, Rachel, Puga Yung, Gisella L., Seebach, Jörg Dieter

“…Summary Regulatory T (Treg) cells induce immunologic tolerance by suppressing effector functions of conventional lymphocytes in the periphery. On the other…”
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