Search Results - "Paczkowski, Filip A."

χ-Conotoxin and Tricyclic Antidepressant Interactions at the Norepinephrine Transporter Define a New Transporter Model by Paczkowski, Filip A., Sharpe, Iain A., Dutertre, Seébastien, Lewis, Richard J.

“…Monoamine neurotransmitter transporters for norepinephrine (NE), dopamine and serotonin are important targets for antidepressants and analgesics. The…”
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Nitric oxide donors inhibit 5‐hydroxytryptamine (5‐HT) uptake by the human 5‐HT transporter (SERT) by Bryan‐Lluka, Lesley J, Papacostas, Marisa H, Paczkowski, Filip A, Wanstall, Janet C

“…The aim was to test the hypothesis that nitric oxide (NO) donor drugs can inhibit the 5‐hydroxytryptamine (5‐HT) transporter, SERT. The NO donors, MAHMA/NO (a…”
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Synthesis and In vitro Biological Activity of Cyclic Lipophilic χ-Conotoxin MrIA Analogues by Dekan, Zoltan, Paczkowski, Filip A., Lewis, Richard J., Alewood, Paul F.

“…The 13-residue peptide, χ-conotoxin MrIA extracted from the venom of Conus marmoreus, is a potent and selective inhibitor of the human noradrenaline…”
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Comparison of the pharmacological properties of cloned rat, human, and bovine norepinephrine transporters by Paczkowski, F A, Bryan-Lluka, L J, Pörzgen, P, Brüss, M, Bönisch, H

“…The aims of this study were to characterize the recently cloned rat norepinephrine transporter (NET) in more detail and in particular to study possible species…”
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Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter by Sucic, Sonja, Paczkowski, Filip A., Runkel, Fabian, Bönisch, Heinz, Bryan‐Lluka, Lesley J.

“…The aim of the study was to investigate the role of glutamate residue 113 in transmembrane domain 2 of the human noradrenaline transporter in determining cell…”
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Effects of short- and long-term exposure to c-AMP and c-GMP on the noradrenaline transporter by Bryan-Lluka, Lesley J., Paczkowski, Filip A., Bönisch, Heinz

“…The effects of short- and long-term exposure of cells to elevated cyclic adenosine monophosphate (c-AMP), using dibutyryl-c-AMP, 8-bromo-c-AMP, cholera toxin…”
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Amino acids involved in differences in the pharmacological profiles of the rat and human noradrenaline transporters by Paczkowski, Filip A, Bryan-Lluka, Lesley J

“…It has been suggested from a previous study in our laboratory that differences in the pharmacology of the species variants of the noradrenaline transporter…”
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Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology by Paczkowski, Filip A, Bryan-Lluka, Lesley J

“…The aim was to examine the functional importance in the norepinephrine transporter (NET) of (i) the phenylalanine residue at position 531 in transmembrane…”
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χ-Conotoxin and Tricyclic Antidepressant Interactions at the Norepinephrine Transporter Define a New Transporter Model by Filip A. Paczkowski, Iain A. Sharpe, Sébastien Dutertre, Richard J. Lewis

“…Monoamine neurotransmitter transporters for norepinephrine (NE), dopamine and serotonin are important targets for antidepressants and analgesics. The…”
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Pharmacological properties of the naturally occurring Ala(457)Pro variant of the human norepinephrine transporter by Paczkowski, Filip A, Bönisch, Heinz, Bryan-Lluka, Lesley J

“…Recently, another research group has reported an almost complete loss of function of the human norepinephrine transporter (hNET) in patients who had…”
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Synthesis and In vitro Biological Activity of Cyclic Lipophilic [chi]-Conotoxin MrIA Analogues by Dekan, Zoltan, Paczkowski, Filip A, Lewis, Richard J, Alewood, Paul F

“…Issue Title: Bruce Merrifield Commemorative Issue The 13-residue peptide, χ-conotoxin MrIA extracted from the venom of Conus marmoreus, is a potent and…”
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Synthesis and In vitro Biological Activity of Cyclic Lipophilic j-Conotoxin MrIA Analogues by Dekan, Zoltan, Paczkowski, Filip A, Lewis, Richard J, Alewood, Paul F

“…The 13-residue peptide, j-conotoxin MrIA extracted from the venom of Conus marmoreus, is a potent and selective inhibitor of the human noradrenaline…”
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Pharmacological properties of the naturally occurring Ala457Pro variant of the human norepinephrine transporter by PACZKOWSKI, Filip A, BÖNISCH, Heinz, BRYAN-LLUKA, Lesley J

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