Search Results - "Pacold, M"

The role of AMP-activated protein kinase in the action of ethanol in the liver by You, Min, Matsumoto, Michinaga, Pacold, Christine M., Cho, Won Kyoo, Crabb, David W.

“…Background & Aims: Our previous work has shown that ethanol induces the fatty acid synthesis pathway by activation of sterol regulatory element-binding protein…”
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The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate by Bravo, J, Karathanassis, D, Pacold, C M, Pacold, M E, Ellson, C D, Anderson, K E, Butler, P J, Lavenir, I, Perisic, O, Hawkins, P T, Stephens, L, Williams, R L

“…More than 50 human proteins with a wide range of functions have a 120 residue phosphoinositide binding module known as the PX domain. The 1.7 A X-ray crystal…”
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Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction by Karathanassis, Dimitrios, Stahelin, Robert V, Bravo, Jerónimo, Perisic, Olga, Pacold, Christine M, Cho, Wonhwa, Williams, Roger L

“…p47(phox) is a key cytosolic subunit required for activation of phagocyte NADPH oxidase. The X-ray structure of the p47(phox) PX domain revealed two distinct…”
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The Supportive and Palliative Radiation Oncology Service: The Impact of a Dedicated Service on Palliative Cancer Care by Krishnan, M.S, Tseng, Y, Sullivan, A, Jones, J, Gorman, D, Taylor, A, Pacold, M, Kalinowski, B, Mamon, H, Balboni, T

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Nanoparticle Formulation of Wortmannin as a Novel Radiosensitizer by Karve, S.S, Werner, M.E, Pacold, M, Sukumar, R, Cummings, N, Wang, A.Z

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Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ by Pacold, Michael E., Suire, Sabine, Perisic, Olga, Lara-Gonzalez, Samuel, Davis, Colin T., Walker, Edward H., Hawkins, Phillip T., Stephens, Len, Eccleston, John F., Williams, Roger L.

“…Ras activation of phosphoinositide 3-kinase (PI3K) is important for survival of transformed cells. We find that PI3Kγ is strongly and directly activated by…”
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Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction by Karathanassis, Dimitrios, Stahelin, Robert V., Bravo, Jerónimo, Perisic, Olga, Pacold, Christine M, Cho, Wonhwa, Williams, Roger L

“…p47phox is a key cytosolic subunit required for activation of phagocyte NADPH oxidase. The X‐ray structure of the p47phox PX domain revealed two distinct basic…”
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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine by Walker, Edward H., Pacold, Michael E., Perisic, Olga, Stephens, Len, Hawkins, Philip T., Wymann, Matthias P., Williams, Roger L.

“…The specific phosphoinositide 3-kinase (PI3K) inhibitors wortmannin and LY294002 have been invaluable tools for elucidating the roles of these enzymes in…”
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Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway by Saxton, R. A., Knockenhauer, K. E., Wolfson, R. L., Chantranupong, L., Pacold, M. E., Wang, T., Schwartz, T. U., Sabatini, D. M.

“…Eukaryotic cells coordinate growth with the availability of nutrients through mTOR complex 1 (mTORC1), a master growth regulator. Leucine is of particular…”
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Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway by Saxton, R. A., Knockenhauer, K. E., Wolfson, R. L., Chantranupong, L., Pacold, M. E., Wang, T., Schwartz, T. U., Sabatini, D. M.

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Molecular Design of Single-Site Metal Alkoxide Catalyst Precursors for Ring-Opening Polymerization Reactions Leading to Polyoxygenates. 1. Polylactide Formation by Achiral and Chiral Magnesium and Zinc Alkoxides, (η3-L)MOR, Where L = Trispyrazolyl- and Trisindazolylborate Ligands by Chisholm, Malcolm H, Eilerts, Nancy W, Huffman, John C, Iyer, Suri S, Pacold, Martha, Phomphrai, Khamphee

“…Single-site achiral and chiral C 3-symmetric complexes LMOR, where M = Mg and Zn, L = an η3-trispyrazolyl- or η3-trisindazolyl-borate ligand and R = Et, tBu,…”
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The Crystal Structure of the PX Domain from p40phox Bound to Phosphatidylinositol 3-Phosphate by Bravo, Jerónimo, Karathanassis, Dimitrios, Pacold, Christine M, Pacold, Michael E, Ellson, Chris D, Anderson, Karen E, Butler, P.Jonathan G, Lavenir, Isabelle, Perisic, Olga, Hawkins, Phillip T, Stephens, Len, Williams, Roger L

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Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance by Babrzadeh, Farbod, Varghese, Vici, Pacold, Mary, Liu, Tommy F, Nyrén, Pål, Schiffer, Celia, Fessel, W Jeffrey, Shafer, Robert W

“…To determine whether pan-protease inhibitor (PI)-resistant virus populations are composed predominantly of viruses with resistance to all PIs or of diverse…”
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Comparison of methods to detect HIV dual infection by Pacold, Mary, Smith, Davey, Little, Susan, Cheng, Pok Man, Jordan, Parris, Ignacio, Caroline, Richman, Douglas, Pond, Sergei Kosakovsky

“…Current methods to detect intraclade HIV dual infection are poorly suited for determining its prevalence in large cohorts. To investigate the potential of…”
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The NADP-linked glyceraldehyde-3-phosphate dehydrogenases of Anabaena variabilis and Synechocystis PCC 6803, which lack one of the cysteines found in the higher plant enzyme, are not reductively activated by Pacold, M E, Stevens, F J, Li, D, Anderson, L E

“…Light activation of NADP-linked glyceraldehyde-3-P dehydrogenase involves reductive cleavage of a disulfide bond. We have proposed that the inactivating…”
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Attorneys' Fees in Class Actions Governed by Fee-Shifting Statutes by Pacold, Martha

“…Calculating the ideal compensation for plaintiffs' attorneys in class actions is difficult. This comment proposes that the rules for setting fees in hybrid…”
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LAB-RADIOBIOLOGY by Floyd, S. R., Pacold, M. E., Clarke, S. M., Blake, E., Fydrych, A., Ho, R., Lee, M. J., Root, D. E., Carpenter, A. E., Sabatini, D. M., French, C. A., Bradner, J. E., Chen, C. C., Yaffe, M. B., Le Rhun, E., Massin, F., Lefevre, A., Bonneterre, J., Bittencourt, M. d. C., Faure, G., Hiramatsu, R., Kawabata, S., Yamada, Y., Miyatake, S.-I., Kuroiwa, T., Li, S., Chou, A. P., Chen, W., Chen, R., Deng, Y., Phillips, H. S., Faull, K. F., Cloughesy, T., Liau, L. M., Lai, A., Mori, K., Ishikura, R., Tomogane, Y., Izumoto, S., Arita, N., Piao, J., Auyeung, G., Policarpio, E., Tabar, V., Yeung, T. P. C., Morrison, L., Hoffman, L., Lee, T.-Y., Bauman, G., Yartsev, S., Ryu, S., Kolozsvary, A., Lapanowski, M., Jenrow, K., Brown, S., Kim, J. H., Brown, R. J., Love, J., Warburton, D., McBride, W., Bluml, S., Ren, X., Vanderwaal, B., Jaboin, J., Baldock, A. L., Anh, S., Rockne, R., Neal, M., Clark-Swanson, K., Sterin, G., Trister, A. D., Malone, H., Ebiana, V., Sonabend, A. M., Mrugala, M., Rockhill, J. K., Silbergeld, D. L., McKhann, G. M., Bruce, J. N., Rostomily, R., Canoll, P., Swanson, K. R., Hawkins-Daarud, A., Baldock, A., Bridge, C., Corwin, D., Mrugala, M. M., Yagle, K., Born, D., Swanson, P.

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Retroviruses and opportunistic infections - 15th annual conference by Pacold, Mary, Soto, Paula

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A public health model for the molecular surveillance of HIV transmission in San Diego, California by SMITH, Davey M, MAY, Susanne J, WOELK, Christopher H, LITTLE, Susan J, TWEETEN, Samantha, DRUMRIGHT, Lydia, PACOLD, Mary E, KOSAKOVSKY POND, Sergei L, PESANO, Rick L, LIE, Yolanda S, RICHMAN, Douglas D, FROST, Simon D. W

“…Current public health efforts often use molecular technologies to identify and contain communicable disease networks, but not for HIV. Here, we investigate how…”
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Clinical, virologic, and immunologic correlates of HIV-1 intraclade B dual infection among men who have sex with men by PACOLD, Mary E, KOSAKOVSKY POND, Sergei L, WAGNER, Gabriel A, DELPORT, Wayne, BOURQUE, Daniel L, RICHMAN, Douglas D, LITTLE, Susan J, SMITH, Davey M

“…To investigate the susceptibilities to and consequences of HIV-1 dual infection. We compared clinical, virologic, and immunologic factors between participants…”
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