Search Results - "Packham, Jonathan"

A randomized placebo-controlled trial of methotrexate in psoriatic arthritis by KINGSLEY, Gabrielle H, KOWALCZYK, Anna, O'KEEFFE, Aidan G, MADDISON, Peter J, SCOTT, David L, TAYLOR, Helen, IBRAHIM, Fowzia, PACKHAM, Jonathan C, MCHUGH, Neil J, MULHERIN, Diarmuid M, KITAS, George D, CHAKRAVARTY, Kuntal, TOM, Brian D. M

“…MTX is widely used to treat synovitis in PsA without supporting trial evidence. The aim of our study was to test the value of MTX in the first large randomized…”
Get full text

Increased Risk of Hypertension Associated with Spondyloarthritis Disease Duration: Results from the ASAS-COMOSPA Study by Derakhshan, Mohammad H, Goodson, Nicola J, Packham, Jonathan C, Sengupta, Raj, Molto, Anna, Marzo-Ortega, Helena, Siebert, Stefan

“…Spondyloarthritis (SpA) is associated with a number of cardiovascular (CV) comorbidities. We examined the association of SpA disease duration and delay in…”
Get full text

Evaluation and validation of a patient completed psoriatic arthritis flare questionnaire by Helliwell, Philip S, Tillett, William, Waxman, Robin, Coates, Laura C, Brooke, Mel, FitzGerald, Oliver, Packham, Jonathan C, McHugh, Neil

“…Evaluation of a psoriatic arthritis (PsA), multidimensional, patient completed disease flare questionnaire (FLARE). The FLARE questionnaire was administered to…”
Get full text

Qualitative interview study exploring the patient experience of living with axial spondyloarthritis and fatigue: difficult, demanding and draining by Pearson, Nathan Ashley, Tutton, Elizabeth, Martindale, J, Strickland, George, Thompson, Jean, Packham, Jonathan C, Creamer, Paul, Haywood, Kirstie

“…ObjectiveTo explore patients’ lived experiences of axial spondyloarthritis (axSpA) and fatigue.DesignInterpretative phenomenological analysis (lived…”
Get full text

Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis by Mattey, Derek L, Packham, Jonathan C, Nixon, Nicola B, Coates, Lucy, Creamer, Paul, Hailwood, Sarah, Taylor, Gordon J, Bhalla, Ashok K

“…The pathology of ankylosing spondylitis (AS) suggests that certain cytokines and matrix metalloproteinases (MMPs) might provide useful markers of disease…”
Get full text

Application of information theoretic feature selection and machine learning methods for the development of genetic risk prediction models by Jalali-najafabadi, Farideh, Stadler, Michael, Dand, Nick, Jadon, Deepak, Soomro, Mehreen, Ho, Pauline, Marzo-Ortega, Helen, Helliwell, Philip, Korendowych, Eleanor, Simpson, Michael A., Packham, Jonathan, Smith, Catherine H., Barker, Jonathan N., McHugh, Neil, Warren, Richard B., Barton, Anne, Bowes, John

“…In view of the growth of clinical risk prediction models using genetic data, there is an increasing need for studies that use appropriate methods to select the…”
Get full text

Assessing fatigue in ankylosing spondylitis: the importance of frequency and severity by Haywood, Kirstie L., Packham, Jonathan C., Jordan, Kelvin P.

“…Objective. The aim of this study was to explore the value of assessing fatigue frequency and its relationship with fatigue severity in a UK cohort of AS…”
Get full text

Relationship Between Smoking and Patient-reported Measures of Disease Outcome in Ankylosing Spondylitis by MATTEY, Derek L, DAWSON, Sarah R, HEALEY, Emma L, PACKHAM, Jonathan C

“…To investigate the relationship between smoking and disease activity, pain, function, and quality of life in patients with ankylosing spondylitis (AS)…”
Get full text

A new era for collaboration? by Packham, Jonathan C, Abraham, Sonya, Kirkham, Bruce, Helliwell, Philip, Siebert, Stefan, Korendowych, Ellie, Fitzgerald, Oliver, Parkinson, Andrew, Brookes, Mel, Coates, Laura, McHugh, Neil

Get full text

Influence of adult height on rheumatoid arthritis: association with disease activity, impairment of joint function and overall disability by Chen, Ying, Yu, Zanzhe, Packham, Jonathan C, Mattey, Derek L

“…To investigate whether normal variation of adult height is associated with clinical characteristics in rheumatoid arthritis (RA), including disease activity…”
Get full text

Development of the Warwick Axial Spondyloarthritis faTigue and Energy questionnaire (WASTEd)—a new patient-reported outcome measure by Pearson, Nathan A, Tutton, Elizabeth, Martindale, Jane, Strickland, George, Thompson, Jean, Packham, Jonathan C, Creamer, Paul, Haywood, Kirstie L

“…Abstract Objective The aim was to co-produce and test a potential new patient-reported outcome measure (PROM), the Warwick Axial Spondyloarthritis faTigue and…”
Get full text

Interaction Between Smoking and Polymorphism in the Promoter Region of the VEGFA Gene Is Associated with Ischemic Heart Disease and Myocardial Infarction in Rheumatoid Arthritis by YING CHEN, DAWES, Peter T, PACKHAM, Jonathan C, MATTEY, Derek L

“…To determine whether variants in the vascular endothelial growth factor A (VEGFA) gene are associated with ischemic heart disease (IHD) and/or myocardial…”
Get full text

Quality and acceptability of patient-reported outcome measures used to assess fatigue in axial spondyloarthritis (axSpA): a systematic review (protocol) by Pearson, Nathan A, Packham, Jonathan C, Parsons, Helen, Haywood, Kirstie L

“…The prevalence of axial spondyloarthritis (axSpA) is estimated between 0.15 and 1.2%, with many of those patients experiencing severe fatigue. Current axSpA…”
Get full text

Effect of Psychological Distress on Continuation of Anti-Tumor Necrosis Factor Therapy in Patients with Rheumatoid Arthritis by MATTEY, Derek L, DAWES, Peter T, HASSELL, Andrew B, BROWNFIELD, Ann, PACKHAM, Jonathan C

“…To investigate the relationship of psychological distress and associated factors with continuation of tumor necrosis factor (TNF) antagonist therapy in…”
Get full text

Optimizing outcomes for ankylosing spondylitis and axial spondyloarthritis patients: a holistic approach to care by Packham, Jonathan

“…Abstract Axial SpA (axSpA) can affect diverse elements of an individual's life. The areas affected can be much more wide-ranging than the historical medical…”
Get full text

Clinical efficacy of oral alendronate in ankylosing spondylitis: a randomised placebo-controlled trial by Coates, Lucy, Packham, Jonathan C, Creamer, Paul, Hailwood, Sarah, Bhalla, Ashley S, Chakravarty, Kuntal, Mulherin, Diamuid, Taylor, Gordon, Mattey, Derek L, Bhalla, Ashok K

“…A prospective, double blind, randomised, placebo controlled trial over 2 years was performed to test the efficacy of alendronate, an oral aminobisphosphonate,…”
Get full text

Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL): Reliability and Validity of a New Patient-reported Outcome Measure by HAYWOOD, Kirstie L, GARRATT, Andrew M, JORDAN, Kelvin P, HEALEY, Emma L, PACKHAM, Jonathan C

“…There is currently no universally accepted measure of quality of life in ankylosing spondylitis (AS). Our objective was to develop and evaluate a…”
Get full text

Assessing fatigue in adults with axial spondyloarthritis: a systematic review of the quality and acceptability of patient-reported outcome measures by Pearson, Nathan A, Packham, Jonathan C, Tutton, Elizabeth, Parsons, Helen, Haywood, Kirstie L

“…Abstract Objective The aim was to evaluate the quality and acceptability of patient-reported outcome measures used to assess fatigue in patients with axial…”
Get full text

AxSpA patients who also meet criteria for fibromyalgia: identifying distinct patient clusters using data from a UK national register (BSRBR-AS) by Macfarlane, Gary J, Pathan, Ejaz, Siebert, Stefan, Packham, Jonathan, Gaffney, Karl, Choy, Ernest, Sengupta, Raj, Atzeni, Fabiola, Martin, Kathryn R, Jones, Gareth T, Dean, Linda E

“…Around 1 in 8 patients with axial spondyloarthritis (axSpA) also meet criteria for fibromyalgia and such patients have considerable unmet need. Identifying…”
Get full text

Séance and technology: intermundane communication as a methodology for contemporary music by Packham, Jonathan

Get full text