Search Results - "Packer, Lester"

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    Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling by Packer, Lester, Cadenas, Enrique

    “…The role of R-α-lipoic acid as a cofactor (lipoyllysine) in mitochondrial energy metabolism is well established. Lipoic acid non-covalently bound and…”
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    Journal Article
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    Antioxidants, oxidants, and redox impacts on cell function — A tribute to Helmut Sies by Cadenas, Enrique, Packer, Lester, Traber, Maret G.

    Published in Archives of biochemistry and biophysics (01-04-2016)
    “…This article is in tribute to Helmut Sies and is written by his friends from the Oxygen Club of California with personal recollections from each of us: Enrique…”
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    Journal Article
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    Molecular aspects of lipoic acid in the prevention of diabetes complications by Packer, Lester, Kraemer, Klaus, Rimbach, Gerald

    “…α-Lipoic acid (LA) and its reduced form, dihydrolipoic acid, are powerful antioxidants. LA scavenges hydroxyl radicals, hypochlorous acid, peroxynitrite, and…”
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    Journal Article
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    Antioxidant Activities of Pomegranate Fruit Extract and Its Anthocyanidins:  Delphinidin, Cyanidin, and Pelargonidin by Noda, Yasuko, Kaneyuki, Takao, Mori, Akitane, Packer, Lester

    Published in Journal of agricultural and food chemistry (02-01-2002)
    “…Antioxidant activities of freeze-dried preparations of a 70% acetone extract of pomegranate (Punica granatum L.) and its three major anthocyanidins…”
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    Journal Article
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    Antioxidant and redox regulation of gene transcription by Sen, C K, Packer, L

    Published in The FASEB journal (01-05-1996)
    “…Reactive oxygen species (ROS) are implicated in the pathogenesis of a wide variety of human diseases. Recent evidence suggests that at moderately high…”
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    Journal Article
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    Thiol homeostasis and supplements in physical exercise by SEN, C. K, PACKER, L

    Published in The American journal of clinical nutrition (01-08-2000)
    “…Thiols are a class of organic sulfur derivatives (mercaptans) characterized by the presence of sulfhydryl residues. In biological systems, thiols have numerous…”
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    Conference Proceeding Journal Article
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    Oxidative-inflammatory damage in cirrhosis: Effect of vitamin E and a fermented papaya preparation by Marotta, Francesco, Yoshida, Chisato, Barreto, Rafael, Naito, Yasuhiro, Packer, Lester

    Published in Journal of gastroenterology and hepatology (01-05-2007)
    “…Background and Aim:  Oxidative DNA damage occurs as an early event in hepatitis C virus (HCV) infection and is an indication of the potential for…”
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    Journal Article
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    The in vivo Neuromodulatory Effects of the Herbal Medicine Ginkgo Biloba by Coran M. H. Watanabe, Wolffram, Siegfried, Ader, Peter, Rimbach, Gerald, Packer, Lester, Maguire, John J., Schultz, Peter G., Gohil, Kishorchandra

    “…Extracts of Ginkgo biloba leaves are consumed as dietary supplements to counteract chronic, age-related neurological disorders. We have applied high-density…”
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    Journal Article
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    Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction by Li, Xuesen, Liu, Zhongbo, Luo, Cheng, Jia, Haiqun, Sun, Lijuan, Hou, Bei, Shen, Weili, Packer, Lester, Cotman, Carl W., Liu, Jiankang

    Published in Free radical biology & medicine (01-04-2008)
    “…α-Lipoic acid (LA) has been widely studied as an agent for preventing and treating various diseases associated with oxidative disruption of mitochondrial…”
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    Journal Article
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    Antioxidants and the response of skin to oxidative stress: vitamin E as a key indicator by Packer, Lester, Valacchi, Giuseppe

    “…As the outermost barrier of the body, the skin is directly and frequently exposed to a prooxidative environment, including solar UVA and UVB radiation, and air…”
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    Journal Article
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    Sebaceous Gland Secretion is a Major Physiologic Route of Vitamin E Delivery to Skin by Packer, Lester, Weber, Stefan U., Thiele, Jens J.

    Published in Journal of investigative dermatology (01-12-1999)
    “…Skin plays an important part in the protection against oxidative stressors, such as ultraviolet radiation, ozone, and chemicals. This study was based on the…”
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    Journal Article Conference Proceeding
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    Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence-accelerated mouse by Rebrin, Igor, Zicker, Steven, Wedekind, Karen J, Paetau-Robinson, Inke, Packer, Lester, Sohal, Rajindar S

    Published in Free radical biology & medicine (15-08-2005)
    “…The main purpose of this study was to investigate whether consumption of diets enriched in antioxidants attenuates the level of oxidative stress in the…”
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    Journal Article
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    Increased Atherosclerosis in Hyperlipidemic Mice Deficient in α-Tocopherol Transfer Protein and Vitamin E by Terasawa, Y, Ladha, Z, Leonard, S W, Morrow, J D, Newland, D, Sanan, D, Packer, L, Traber, M G, Farese, Jr, R V

    “…Although lipid peroxidation in the subendothelial space has been hypothesized to play a central role in atherogenesis, the role of vitamin E in preventing…”
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    Journal Article
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    Antioxidant activity of nasunin, an anthocyanin in eggplant peels by Noda, Yasuko, Kneyuki, Takao, Igarashi, Kiharu, Mori, Akitane, Packer, Lester

    Published in Toxicology (Amsterdam) (07-08-2000)
    “…The free radical scavenging activities and inhibitory effect of lipid peroxidation of a delphinidin derivative in eggplant were investigated. Delphinidin-3-(…”
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    Journal Article Conference Proceeding
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    Antioxidant Supplementation Decreases Lipid Peroxidation Biomarker F2-isoprostanes in Plasma of Smokers by DIETRICH, Marion, BLOCK, Gladys, HUDES, Mark, MORROW, Jason D, NORKUS, Edward P, TRABER, Maret G, CROSS, Carroll E, PACKER, Lester

    “…Free radicals in cigarette smoke (CS) cause oxidative damage to proteins, DNA, and lipids, contributing to the pathobiology of atherosclerosis, heart disease,…”
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    Journal Article
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    Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid by Shen, Weili, Liu, Kai, Tian, Chuan, Yang, Lu, Li, Xuesen, Ren, Jinmin, Packer, Lester, Head, Elizabeth, Sharman, Edward, Liu, Jiankang

    Published in Journal of cellular biochemistry (01-07-2008)
    “…Mitochondrial dysfunction due to oxidative stress and concomitant impaired β‐cell function may play a key role in type 2 diabetes. Preventing and/or…”
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    Journal Article
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