Search Results - "Packeiser, Eva‐Maria"
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Uterine prolapse in a non‐pregnant bitch
Published in Reproduction in domestic animals (01-12-2023)“…A ten‐year‐old mixed breed bitch was presented for a tissue prolapse protruding from her vulva. Following detailed examination and stabilization, the ovaries…”
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Metformin and sodium dichloroacetate effects on proliferation, apoptosis, and metabolic activity tested alone and in combination in a canine prostate and a bladder cancer cell line
Published in PloS one (27-09-2021)“…An important approach in tumor therapy is combining substances with different action mechanisms aiming to enhance the antineoplastic effect, decrease the…”
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3
MDR1 Inhibition Reverses Doxorubicin-Resistance in Six Doxorubicin-Resistant Canine Prostate and Bladder Cancer Cell Lines
Published in International journal of molecular sciences (02-05-2023)“…Acquired chemoresistance during chemotherapy, often accompanied by cross- and multi-resistance, limits therapeutic outcomes and leads to recurrence. In order…”
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4
Insights into Canine Infertility: Apoptosis in Chronic Asymptomatic Orchitis
Published in International journal of molecular sciences (23-03-2023)“…Chronic asymptomatic orchitis (CAO) is a common cause of acquired non-obstructive azoospermia in dogs. To understand the impact and mode of action of…”
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Characterization of six canine prostate adenocarcinoma and three transitional cell carcinoma cell lines derived from primary tumor tissues as well as metastasis
Published in PloS one (13-03-2020)“…Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC) of prostate and urinary bladder are highly invasive and metastatic tumors of closely…”
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Involvement of Oxytocin and Progesterone Receptor Expression in the Etiology of Canine Uterine Inertia
Published in International journal of molecular sciences (01-11-2022)“…An altered oxytocin and progesterone receptor (OXTR and PGR, respectively) expression was postulated in canine uterine inertia (UI), which is the lack of…”
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An RNA-Seq-Based Framework for Characterizing Canine Prostate Cancer and Prioritizing Clinically Relevant Biomarker Candidate Genes
Published in International journal of molecular sciences (25-10-2021)“…Prostate cancer (PCa) in dogs is a highly malignant disease akin to its human counterpart. In contrast to the situation in humans, multi-gene approaches…”
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Evaluation of the therapeutic potential of masitinib and expression of its specific targets c‐Kit, PDGFR‐α, PDGFR‐β, and Lyn in canine prostate cancer cell lines
Published in Veterinary & comparative oncology (01-09-2022)“…Canine prostate cancer is classified into adenocarcinoma, transitional cell carcinoma with prostatic involvement, and mixed forms. Early metastatic spread…”
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Detection of spermatogonial stem cells in testicular tissue of dogs with chronic asymptomatic orchitis
Published in Frontiers in veterinary science (15-06-2023)“…Chronic asymptomatic idiopathic orchitis (CAO) is an important but neglected cause of acquired infertility due to non-obstructive azoospermia (NOA) in male…”
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10
Evaluation of new and old biomarkers in dogs with degenerative mitral valve disease
Published in BMC veterinary research (02-07-2022)“…Background Dogs with degenerative mitral valve disease are commonly presented to small animal clinicians. Diagnosis, clinical staging, and therapeutic design…”
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Cross-Species Comparison of the Pan-RAF Inhibitor LY3009120's Anti-Tumor Effects in Equine, Canine, and Human Malignant Melanoma Cell Lines
Published in Genes (01-02-2024)“…Malignant melanomas (MMs) are the abnormal proliferation of melanocytes and are one of the lethal skin cancers in humans, equines, and canines. Accordingly,…”
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RNA-seq of nine canine prostate cancer cell lines reveals diverse therapeutic target signatures
Published in Cancer cell international (02-02-2022)“…Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC) are typically characterized by metastasis and chemoresistance. Cell lines are…”
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13
Isoquinolinamine FX-9 Exhibits Anti-Mitotic Activity in Human and Canine Prostate Carcinoma Cell Lines
Published in International journal of molecular sciences (07-11-2019)“…Current therapies are insufficient for metastatic prostate cancer (PCa) in men and dogs. As human castrate-resistant PCa shares several characteristics with…”
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14
The In Vitro Contractile Response of Canine Pregnant Myometrium to Oxytocin and Denaverine Hydrochloride
Published in Biology (Basel, Switzerland) (01-06-2023)“…In pregnant bitches, the response to oxytocin and denaverine hydrochloride in dystocia management is usually poor. To better understand the effect of both…”
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Analysis of gene and protein expression in the endometrium for validation of an ex vivo model of the equine uterus using PCR, digital and visual histopathology
Published in Theriogenology (01-06-2024)“…In the past, most research in equine reproduction has been performed in vivo but the use of in vitro and ex vivo models has recently increased. This study…”
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Alterations in Tumor Aggression Following Androgen Receptor Signaling Restoration in Canine Prostate Cancer Cell Lines
Published in International journal of molecular sciences (07-08-2024)“…In prostate cancer (PCa), androgens upregulate tumorigenesis, whereas in benign tissue, the revival of androgen receptor (AR) signaling suppresses aggressive…”
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Insights into the role of PGF2α in canine periparturient myometrium
Published in Frontiers in physiology (28-05-2024)“…Parturition in dogs is subjected to complex hormonal regulation, with the involvement of prostaglandin F2α (PGF2α) still not fully understood. To investigate…”
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Proteomic analysis of extracellular vesicles derived from canine mammary tumour cell lines identifies protein signatures specific for disease state
Published in BMC veterinary research (26-10-2024)“…Canine mammary tumours (CMT) are among the most common types of tumours in female dogs. Diagnosis currently requires invasive tissue biopsies and histological…”
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Reproductive Management in Catteries: Optimising health and wellbeing through veterinarian-breeder collaboration
Published in Journal of Feline Medicine and Surgery (01-09-2022)“…Practical relevance: Many veterinarians – even those engaged in small animal reproduction – are uncomfortable with taking care of cat breeders or being in…”
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