Search Results - "Packard, C. J"

Measurement and meaning of apolipoprotein AI and apolipoprotein B plasma levels by MARCOVINA, S., PACKARD, C. J.

“… Apolipoproteins AI and B are structural components of lipoprotein particles, and also determinants of the metabolic fate of the encapsulated lipid,…”
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Investigation of human apoB48 metabolism using a new, integrated non‐steady‐state model of apoB48 and apoB100 kinetics by Björnson, E., Packard, C. J., Adiels, M., Andersson, L., Matikainen, N., Söderlund, S., Kahri, J., Sihlbom, C., Thorsell, A., Zhou, H., Taskinen, M.‐R., Borén, J.

“…Background Triglyceride‐rich lipoproteins and their remnants have emerged as major risk factors for cardiovascular disease. New experimental approaches are…”
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Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty‐person/ten‐country panel by BARTER, P. J., BALLANTYNE, C. M., CARMENA, R., CABEZAS, M. CASTRO, CHAPMAN, M. JOHN, COUTURE, P., GRAAF, J., DURRINGTON, P. N., FAERGEMAN, O., FROHLICH, J., FURBERG, C. D., GAGNE, C., HAFFNER, S. M., HUMPHRIES, S. E., JUNGNER, I., KRAUSS, R. M., KWITEROVICH, P., MARCOVINA, S., PACKARD, C. J., PEARSON, T. A., REDDY, K. SRINATH, ROSENSON, R., SARRAFZADEGAN, N., SNIDERMAN, A. D., STALENHOEF, A. F., STEIN, E., TALMUD, P. J., TONKIN, A. M., WALLDIUS, G., WILLIAMS, K. M. S.

“… There is abundant evidence that the risk of atherosclerotic vascular disease is directly related to plasma cholesterol levels. Accordingly, all of the…”
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Triacylglycerol-rich lipoproteins and the generation of small, dense low-density lipoprotein by Packard, C J

“…LDL (low-density lipoprotein) is the major carrier of cholesterol in human plasma, and as such is intimately involved in the process of atherosclerosis. The…”
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Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men by Skogsberg, J., McMahon, A. D., Karpe, F., Hamsten, A., Packard, C. J., Ehrenborg, E.

“… Objectives.  Peroxisome proliferator activated receptor delta (PPARD) is a transcription factor implicated in the regulation of genes involved in cholesterol…”
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Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM by MALMSTRÖM, R, PACKARD, C. J, CASLAKE, M, BEDFORD, D, STEWART, P, YKI-JÄRVINEN, H, SHEPHERD, J, TASKINEN, M.-R

“…Insulin administration to healthy subjects inhibits the production of very low density lipoprotein (VLDL)1 (Svedbergs flotation (Sf) rate 60-400) without…”
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Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters by Pirwany, I. R., Fleming, R., Greer, I. A., Packard, C. J., Sattar, N.

“…OBJECTIVE Women with polycystic ovary syndrome (PCOS) exhibit an abnormal lipoprotein profile, characterized by raised concentrations of plasma triglyceride,…”
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Exercise training has greater effects on insulin sensitivity in daughters of patients with type 2 diabetes than in women with no family history of diabetes by Barwell, N. D, Malkova, D, Moran, C. N, Cleland, S. J, Packard, C. J, Zammit, V. A, Gill, J. M. R

“…Aims/hypothesis Sedentary offspring of patients with type 2 diabetes are often more insulin-resistant than persons with no family history of diabetes, but when…”
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Genetic variation in the interleukin-1β-converting enzyme associates with cognitive function. The PROSPER study by Trompet, S., de Craen, A. J. M., Slagboom, P., Shepherd, J., Blauw, G. J., Murphy, M. B., Bollen, E. L. E. M., Buckley, B. M., Ford, I., Gaw, A., Macfarlane, P. W., Packard, C. J., Stott, D. J., Jukema, J. W., Westendorp, R. G. J.

“…Inflammation is thought to play an important role in the development of cognitive decline and dementia in old age. The interleukin-1 signalling pathway may…”
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Lipoprotein Heterogeneity and Apolipoprotein B Metabolism by Packard, Chris J, Shepherd, James

“…The apolipoprotein B containing lipoproteins VLDL, IDL, and LDL exhibit variation in their structure, function, and metabolism. These major lipoprotein classes…”
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Apolipoprotein B metabolism and the distribution of VLDL and LDL subfractions by Packard, C J, Demant, T, Stewart, J P, Bedford, D, Caslake, M J, Schwertfeger, G, Bedynek, A, Shepherd, J, Seidel, D

“…Apolipoprotein B (apoB) metabolism was investigated in 20 men with plasma triglyceride 0.66-2.40 mmol/l and plasma cholesterol 3.95-6. 95 mmol/l. Kinetics of…”
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Testing cognitive function in elderly populations: the PROSPER study by Houx, P J, Shepherd, J, Blauw, G-J, Murphy, M B, Ford, I, Bollen, E L, Buckley, B, Stott, D J, Jukema, W, Hyland, M, Gaw, A, Norrie, J, Kamper, A M, Perry, I J, MacFarlane, P W, Meinders, A Edo, Sweeney, B J, Packard, C J, Twomey, C, Cobbe, S M, Westendorp, R G

“…Objectives: For large scale follow up studies with non-demented patients in which cognition is an endpoint, there is a need for short, inexpensive, sensitive,…”
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Influence of plasma lipid and LDL-subfraction profile on the interaction between low density lipoprotein with human arterial wall proteoglycans by Anber, V., Griffin, B.A., McConnell, M., Packard, C.J., Shepherd, J.

“…Low density lipoprotein (LDL) is known to bind to arterial wall proteoglycans (APG), an interaction which may initiate cholesterol deposition in the arterial…”
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Effects of insulin and acipimox on VLDL1 and VLDL2 apolipoprotein B production in normal subjects by Malmström, R, Packard, C J, Caslake, M, Bedford, D, Stewart, P, Yki-Järvinen, H, Shepherd, J, Taskinen, M R

“…Effects of insulin and acipimox on VLDL1 and VLDL2 apolipoprotein B production in normal subjects. R Malmström , C J Packard , M Caslake , D Bedford , P…”
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Prospective analysis of the association of infection with CagA bearing strains of Helicobacter pylori and coronary heart disease by Singh, R K, McMahon, A D, Patel, H, Packard, C J, Rathbone, B J, Samani, N J

“…Objective: To see whether it was possible to replicate in a prospective study the association recently reported between infection with the more virulent (type…”
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Apolipoprotein B48 metabolism in chylomicrons and very low‐density lipoproteins and its role in triglyceride transport in normo‐ and hypertriglyceridemic human subjects by Björnson, E., Packard, C.J., Adiels, M., Andersson, L., Matikainen, N., Söderlund, S., Kahri, J., Hakkarainen, A., Lundbom, N., Lundbom, J., Sihlbom, C., Thorsell, A., Zhou, H., Taskinen, M.‐R., Borén, J.

“…Background Renewed interest in triglyceride‐rich lipoproteins as causative agents in cardiovascular disease mandates further exploration of the integrated…”
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Plasma C reactive protein concentration indicates a direct relation between systemic inflammation and social deprivation by St J O’Reilly, D, Upton, M N, Caslake, M J, Robertson, M, Norrie, J, McConnachie, A, Watt, G C M, Packard, C J

“…An increase in the plasma concentration of C reactive protein (CRP), within the reference range for the population but below the threshold that indicates…”
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Overview of fenofibrate by PACKARD, C. J

“…Fenofibrate is a broad spectrum lipid-lowering agent able to produce substantial reductions in plasma triglyceride and low density lipoprotein (LDL) and an…”
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Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly by Sattar, N, Murray, H. M, Welsh, P, Blauw, G. J, Buckley, B. M, de Craen, A. J, Ford, I, Forouhi, N. G, Freeman, D. J, Jukema, J. W, Macfarlane, P. W, Murphy, M. B, Packard, C. J, Stott, D. J, Westendorp, R. G. J, Shepherd, J

“…Aims/hypothesis The aim of this prospective study was to determine whether circulating intercellular adhesion molecule (ICAM) 1, as a potential surrogate of…”
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Interaction of Very-Low-Density, Intermediate-Density, and Low-Density Lipoproteins With Human Arterial Wall Proteoglycans by Anber, V, Millar, J.S, McConnell, M, Shepherd, J, Packard, C.J

“…The specific interaction of lipoproteins with arterial wall constituents, particularly proteoglycans (APG), is believed to play an important role in the…”
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