Search Results - "Pacios, Luis F."

Arabidopsis immune responses triggered by cellulose‐ and mixed‐linked glucan‐derived oligosaccharides require a group of leucine‐rich repeat malectin receptor kinases by Martín‐Dacal, Marina, Fernández‐Calvo, Patricia, Jiménez‐Sandoval, Pedro, López, Gemma, Garrido‐Arandía, María, Rebaque, Diego, Hierro, Irene, Berlanga, Diego José, Torres, Miguel Ángel, Kumar, Varun, Mélida, Hugo, Pacios, Luis F., Santiago, Julia, Molina, Antonio

“…SUMMARY The plant immune system perceives a diversity of carbohydrate ligands from plant and microbial cell walls through the extracellular ectodomains (ECDs)…”
Get full text

A computational structural study on the DNA-protecting role of the tardigrade-unique Dsup protein by Mínguez-Toral, Marina, Cuevas-Zuviría, Bruno, Garrido-Arandia, María, Pacios, Luis F.

“…The remarkable ability of tardigrades to withstand a wide range of physical and chemical extremes has attracted a considerable interest in these small…”
Get full text

The major cow milk allergen Bos d 5 manipulates T-helper cells depending on its load with siderophore-bound iron by Roth-Walter, Franziska, Pacios, Luis F, Gomez-Casado, Cristina, Hofstetter, Gerlinde, Roth, Georg A, Singer, Josef, Diaz-Perales, Araceli, Jensen-Jarolim, Erika

“…The mechanisms of allergic sensitization to milk are still elusive. The major allergen Bos d 5 belongs to the lipocalin-family and thus is able to transport…”
Get full text

Arabidopsis Cell Cycle F-Box Protein SKP2A Binds to Auxin by Jurado, Silvia, Abraham, Zamira, Manzano, Concepción, López-Torrejón, Gema, Pacios, Luis F, Del Pozo, Juan C

“…Arabidopsis thaliana S-Phase Kinase-Associated Protein 2A (SKP2A) is an F-box protein that regulates the proteolysis of cell cycle transcription factors. The…”
Get full text

Bet v 1 from Birch Pollen Is a Lipocalin-like Protein Acting as Allergen Only When Devoid of Iron by Promoting Th2 Lymphocytes by Roth-Walter, Franziska, Gomez-Casado, Cristina, Pacios, Luis F., Mothes-Luksch, Nadine, Roth, Georg A., Singer, Josef, Diaz-Perales, Araceli, Jensen-Jarolim, Erika

“…It is hypothesized that allergens are at the borderline of self and non-self and, through as yet elusive circumstances, mount a Th2 response for allergic…”
Get full text

Energy Landscapes of Ligand Motion Inside the Tunnel-Like Cavity of Lipid Transfer Proteins: The Case of the Pru p 3 Allergen by Cuevas-Zuviría, Bruno, Garrido-Arandia, María, Díaz-Perales, Araceli, Pacios, Luis F

“…Allergies are a widespread problem in western countries, affecting a large part of the population, with levels of prevalence increasingly rising due to reasons…”
Get full text

Differences in the Elastomeric Behavior of Polyglycine-Rich Regions of Spidroin 1 and 2 Proteins by Pacios, Luis F, Arguelles, Joseph, Hayashi, Cheryl Y, Guinea, Gustavo V, Elices, Manuel, Perez-Rigueiro, Jose

“…Two different polyglycine-rich fragments were selected as representatives of major ampullate gland spidroins (MaSp) 1 and 2 types, and their behavior in a…”
Get full text

A Comparative Study of Human Saposins by Garrido-Arandia, María, Cuevas-Zuviría, Bruno, Díaz-Perales, Araceli, Pacios, Luis F

“…Saposins are small proteins implicated in trafficking and loading of lipids onto Cluster of Differentiation 1 (CD1) receptor proteins that in turn present…”
Get full text

Expression and Interaction Analysis among Saffron ALDHs and Crocetin Dialdehyde by Gómez-Gómez, Lourdes, Pacios, Luis F, Diaz-Perales, Araceli, Garrido-Arandia, María, Argandoña, Javier, Rubio-Moraga, Ángela, Ahrazem, Oussama

“…In saffron, the cleavage of zeaxanthin by means of CCD2 generates crocetin dialdehyde, which is then converted by an unknown aldehyde dehydrogenase to…”
Get full text

Wheat lipid transfer protein is a major allergen associated with baker's asthma by Palacin, Arantxa, PhD, Quirce, Santiago, MD, PhD, Armentia, Alicia, MD, PhD, Fernández-Nieto, Mar, MD, Pacios, Luis F., PhD, Asensio, Teresa, MD, Sastre, Joaquin, MD, PhD, Diaz-Perales, Araceli, PhD, Salcedo, Gabriel, PhD

“…Background Baker's asthma is a frequent occupational allergic disorder mainly caused by inhalation of cereal flours. Lipid transfer proteins (LTPs) constitute…”
Get full text

Structure-Based Multifunctionalization of Flexuous Elongated Viral Nanoparticles by Yuste-Calvo, Carmen, González-Gamboa, Ivonne, Pacios, Luis F, Sánchez, Flora, Ponz, Fernando

“…Nanoparticle multifunctionalization has become an important goal in many nanoscience-related areas because it allows different simultaneous applications with…”
Get full text

Secretory protein beta‐lactoglobulin in cattle stable dust may contribute to the allergy‐protective farm effect by Pali‐Schöll, Isabella, Bianchini, Rodolfo, Afify, Sheriene Moussa, Hofstetter, Gerlinde, Winkler, Simona, Ahlers, Stella, Altemeier, Theresa, Mayerhofer, Hanna, Hufnagl, Karin, Korath, Anna D. J., Pranger, Christina, Widhalm, Raimund, Hann, Stephan, Wittek, Thomas, Kasper‐Giebl, Anne, Pacios, Luis F., Roth‐Walter, Franziska, Vercelli, Donata, Mutius, Erika, Jensen‐Jarolim, Erika

“…Background Growing up on a cattle farm and consuming raw cow's milk protects against asthma and allergies. We expect a cattle‐specific protein as active…”
Get full text

Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: Peach Pru p 3 allergen as a model by Pacios, Luis F., Tordesillas, Leticia, Cuesta-Herranz, Javier, Compes, Esther, Sánchez-Monge, Rosa, Palacín, Arantxa, Salcedo, Gabriel, Díaz-Perales, Araceli

“…Lipid transfer proteins (LTPs) are the major allergens of Rosaceae fruits in the Mediterranean area. Pru p 3, the LTP and major allergen of peach, is a…”
Get full text

Structural Dynamics of the Lipid Antigen-Binding Site of CD1d Protein by Cuevas-Zuviría, Bruno, Mínguez-Toral, Marina, Díaz-Perales, Araceli, Garrido-Arandia, María, Pacios, Luis F

“…CD1 molecules present lipid antigens to T-cells in early stages of immune responses. Whereas CD1‒lipid‒T-cell receptors interactions are reasonably understood,…”
Get full text

Machine Learning of Analytical Electron Density in Large Molecules Through Message-Passing by Cuevas-Zuviría, Bruno, Pacios, Luis F

“…Machine learning milestones in computational chemistry are overshadowed by their unaccountability and the overwhelming zoo of tools for each specific task. A…”
Get full text

IgG4 Drives M2 Macrophages to Cortisol, Lcn-2 and IL-10 Release: Implications in Maintenance of Tolerance and Allergen Immunotherapy by Jensen-Jarolim, Erika, Prof, Roth-Walter, Franziska, PhD, Ass.Prof, Pacios, Luis F., Prof, Wagner, Stefanie, MSc, BSc, Glenk, Lisa-Maria, Dr, Hofstetter, Gerlinde, MSc, BSc, Palme, Rupert, Prof, Roth, Georg A., Prof, Hufnagl, Karin, PhD, Bianchini, Rodolfo, PhD

“…Only IgG4 is leading to cortisol, LCN-2 and IL-10 secretion. [...]exogenous unloaded lipocalin allergens may lower the levels of bioavailable cortisol, and…”
Get full text

Analytical Model of Electron Density and Its Machine Learning Inference by Cuevas-Zuviría, Bruno, Pacios, Luis F

“…We present an analytical model representation of the electron density ρ­(r) in molecules in the form of expansions of a few functions (exponentials and a…”
Get full text

Non-branched [beta]-1,3-glucan oligosaccharides trigger immune responses in Arabidopsis by Melida, Hugo, Sopena-Torres, Sara, Bacete, Laura, Garrido-Arandia, María, Jorda, Lucía, Lopez, Gemma, Munoz-Barrios, Antonio, Pacios, Luis F, Molina, Antonio

“…Summary Fungal cell walls, which are essential for environmental adaptation and host colonization by the fungus, have been evolutionarily selected by plants…”
Get full text

Intrinsic disorder in the dynamic evolution of structure, stability, and flexibility of potyviral VLP assemblies: A computational study by Pacios, Luis F, Sánchez, Flora, Ponz, Fernando

“…An all-atom Molecular Dynamics (MD) study was applied to three viral nanoparticles (VLPs) of Turnip mosaic virus (TuMV), a potyvirus: the particles genetically…”
Get full text

Cow’s milk protein β-lactoglobulin confers resilience against allergy by targeting complexed iron into immune cells by Roth-Walter, Franziska, Afify, Sheriene Moussa, Pacios, Luis F., Blokhuis, Bart R., Redegeld, Frank, Regner, Andreas, Petje, Lisa-Marie, Fiocchi, Alessandro, Untersmayr, Eva, Dvorak, Zdenek, Hufnagl, Karin, Pali-Schöll, Isabella, Jensen-Jarolim, Erika

“…Beta-lactoglobulin (BLG) is a bovine lipocalin in milk with an innate defense function. The circumstances under which BLG is associated with tolerance of or…”
Get full text