Search Results - "Pacienza"

The Morrison–Kawamata cone conjecture for singular symplectic varieties by Lehn, Christian, Mongardi, Giovanni, Pacienza, Gianluca

“…We prove the Morrison–Kawamata cone conjecture for projective primitive symplectic varieties with Q -factorial and terminal singularities with b 2 ≥ 5 , from…”
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Corrigendum and Addendum to “Polarized Parallel Transport and Uniruled Divisors on Generalized Kummer Varieties” by Mongardi, Giovanni, Pacienza, Gianluca

“…We correct the statement of the main result of [9] and provide some further precisions…”
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Polarized Parallel Transport and Uniruled Divisors on Deformations of Generalized Kummer Varieties by Mongardi, Giovanni, Pacienza, Gianluca

“…Abstract In this note, we characterize polarized parallel transport operators on irreducible holomorphic symplectic varieties which are deformations of…”
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CD9: A possible clue into breast cancer chemoresistance by Pacienza, Natalia, Yannarelli, Gustavo

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Ion exchange chromatography as a simple and scalable method to isolate biologically active small extracellular vesicles from conditioned media by Malvicini, Ricardo, Santa-Cruz, Diego, Tolomeo, Anna Maria, Muraca, Maurizio, Yannarelli, Gustavo, Pacienza, Natalia

“…In the last few years, extracellular vesicles (EVs) have become of great interest due to their potential as biomarkers, drug delivery systems, and, in…”
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Bone marrow/bone pre-metastatic niche for breast cancer cells colonization: The role of mesenchymal stromal cells by Sanmartin, M.C., Borzone, F.R., Giorello, M.B., Pacienza, N., Yannarelli, G., Chasseing, N.A.

“…[Display omitted] •About 70 % of advanced breast cancer patients develop bone metastasis with a high mortality rate.•Breast cancer cells disrupt bone…”
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OCT4 Silencing Triggers Its Epigenetic Repression and Impairs the Osteogenic and Adipogenic Differentiation of Mesenchymal Stromal Cells by Malvicini, Ricardo, Santa-Cruz, Diego, Pacienza, Natalia, Yannarelli, Gustavo

“…Mechanisms mediating mesenchymal stromal/stem cells' (MSCs) multipotency are unclear. Although the expression of the pluripotency factor OCT4 has been detected…”
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Nitric oxide induces specific isoforms of antioxidant enzymes in soybean leaves subjected to enhanced ultraviolet-B radiation by Santa-Cruz, Diego M., Pacienza, Natalia A., Zilli, Carla G., Tomaro, Maria L., Balestrasse, Karina B., Yannarelli, Gustavo G.

“…•UV-B affects plant growth and development.•Nitric oxide protects against UV-B-induced oxidative stress.•Nitric oxide up-regulates antioxidant enzymes…”
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OCT4 expression mediates partial cardiomyocyte reprogramming of mesenchymal stromal cells by Yannarelli, Gustavo, Pacienza, Natalia, Montanari, Sonia, Santa-Cruz, Diego, Viswanathan, Sowmya, Keating, Armand

“…Mesenchymal stem/stromal cells (MSCs) are in numerous cell therapy clinical trials, including for injured myocardium. Acquisition of cardiomyocyte…”
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Deformations of rational curves on primitive symplectic varieties and applications by Lehn, Christian, Mongardi, Giovanni, Pacienza, Gianluca

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In Vitro Macrophage Assay Predicts the In Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells by Pacienza, Natalia, Lee, Ryang Hwa, Bae, Eun-Hye, Kim, Dong-ki, Liu, Qisong, Prockop, Darwin J., Yannarelli, Gustavo

“…Extracellular vesicles (EVs) play key roles in cell biology and may provide new clinical diagnostics and therapies. However, it has proven difficult to develop…”
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Chromatographic Scalable Method to Isolate Engineered Extracellular Vesicles Derived from Mesenchymal Stem Cells for the Treatment of Liver Fibrosis in Mice by Domínguez, Luciana M, Bueloni, Bárbara, Cantero, Ma José, Albornoz, Milagros, Pacienza, Natalia, Biani, Celeste, Luzzani, Carlos, Miriuka, Santiago, García, Mariana, Atorrasagasti, Catalina, Yannarelli, Gustavo, Bayo, Juan, Fiore, Esteban, Mazzolini, Guillermo

“…New therapeutic options for liver cirrhosis are needed. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have emerged as a promising tool for…”
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Deformations of singular symplectic varieties and termination of the log minimal model program by Lehn, Christian, Pacienza, Gianluca

“…We generalize Huybrechts' theorem on deformation equivalence of birational irreducible symplectic manifolds to the singular setting. More precisely, under…”
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Alendronate inhibits triglyceride accumulation and oxidative stress in adipocytes and the inflammatory response of macrophages which are associated with adipose tissue dysfunction by Martini, Claudia, Sosa, Fernando Nicolas, Malvicini, Ricardo, Pacienza, Natalia, Yannarelli, Gustavo, del C. Vila, María

“…Alendronate, a bisphosphonate used to prevent osteoporosis, stimulates osteogenesis but impairs adipogenesis. Different clinical trials suggest that the…”
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Nitric oxide synthase-like dependent NO production enhances heme oxygenase up-regulation in ultraviolet-B-irradiated soybean plants by Santa-Cruz, Diego M., Pacienza, Natalia A., Polizio, Ariel H., Balestrasse, Karina B., Tomaro, Maria L., Yannarelli, Gustavo G.

“…Nitric oxide is involved in the signaling pathway leading to HO-1 up-regulation under UV-B, and a balance between NO and ROS is important to trigger the…”
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Influence of the isolation method on characteristics and functional activity of mesenchymal stromal cell-derived extracellular vesicles by Malvicini, Ricardo, De Lazzari, Giada, Tolomeo, Anna Maria, Santa-Cruz, Diego, Ullah, Mujib, Cirillo, Carmine, Grumati, Paolo, Pacienza, Natalia, Muraca, Maurizio, Yannarelli, Gustavo

“…Extracellular vesicle (EV) isolation methods are based on different physicochemical properties and may result in the purification of distinct EV populations…”
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Macrophage bioassay standardization to assess the anti-inflammatory activity of mesenchymal stromal cell-derived small extracellular vesicles by Malvicini, Ricardo, Santa-Cruz, Diego, De Lazzari, Giada, Tolomeo, Anna Maria, Sanmartin, Cecilia, Muraca, Maurizio, Yannarelli, Gustavo, Pacienza, Natalia

“…BACKGROUND AIMSOwing to the lack of biological assays, determining the biological activity of extracellular vesicles has proven difficult. Here the authors…”
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Human umbilical cord perivascular cells exhibit enhanced cardiomyocyte reprogramming and cardiac function after experimental acute myocardial infarction by Yannarelli, Gustavo, Dayan, Victor, Pacienza, Natalia, Lee, Chyan-Jang, Medin, Jeffrey, Keating, Armand

“…We were interested in evaluating the ability of the mesenchymal stromal cell (MSC) population, human umbilical cord perivascular cells (HUCPVCs), to undergo…”
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Novel and safe single-dose treatment of cutaneous leishmaniasis with implantable amphotericin B-loaded microparticles by Sousa-Batista, Ariane J., Pacienza-Lima, Wallace, Ré, Maria Inês, Rossi-Bergmann, Bartira

“…The development of an effective amphotericin B (AmB) topical formulation to replace the systemically toxic injections currently used in cutaneous leishmaniasis…”
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Uniruledness of stable base loci of adjoint linear systems via Mori theory by Boucksom, Sébastien, Broustet, Amaël, Pacienza, Gianluca

“…We explain how to deduce from recent results in the Minimal Model Program a general uniruledness theorem for base loci of adjoint divisors. As a special case,…”
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