Search Results - "Pacia, Christopher P"

Characterization of the Targeting Accuracy of a Neuronavigation-guided Transcranial FUS system in vitro, in vivo, and in silico by Xu, Lu, Pacia, Christopher P., Gong, Yan, Hu, Zhongtao, Chien, Chih-Yen, Yang, Leqi, Gach, H. Michael, Hao, Yao, Comron, Hassanzadeh, Huang, Jiayi, Leuthardt, Eric C., Chen, Hong

“…Focused ultrasound (FUS)-enabled liquid biopsy (sonobiopsy) is an emerging technique for the noninvasive and spatiotemporally controlled diagnosis of brain…”
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Sonobiopsy for minimally invasive, spatiotemporally-controlled, and sensitive detection of glioblastoma-derived circulating tumor DNA by Pacia, Christopher P, Yuan, Jinyun, Yue, Yimei, Xu, Lu, Nazeri, Arash, Desai, Rupen, Gach, H Michael, Wang, Xiaowei, Talcott, Michael R, Chaudhuri, Aadel A, Dunn, Gavin P, Leuthardt, Eric C, Chen, Hong

“…Though surgical biopsies provide direct access to tissue for genomic characterization of brain cancer, they are invasive and pose significant clinical risks…”
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Estimation of Anisotropic Material Properties of Soft Tissue by MRI of Ultrasound-Induced Shear Waves by Guertler, Charlotte A, Okamoto, Ruth J, Ireland, Jake A, Pacia, Christopher P, Garbow, Joel R, Chen, Hong, Bayly, Philip V

“…This paper describes a new method for estimating anisotropic mechanical properties of fibrous soft tissue by imaging shear waves induced by focused ultrasound…”
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Leptomeningeal disease and tumor dissemination in a murine diffuse intrinsic pontine glioma model: implications for the study of the tumor-cerebrospinal fluid-ependymal microenvironment by Pan, Shelei, Ye, Dezhuang, Yue, Yimei, Yang, Lihua, Pacia, Christopher P, DeFreitas, Dakota, Esakky, Prabagaran, Dahiya, Sonika, Limbrick, David D, Rubin, Joshua B, Chen, Hong, Strahle, Jennifer M

“…Abstract Background Leptomeningeal disease and hydrocephalus are present in up to 30% of patients with diffuse intrinsic pontine glioma (DIPG), however there…”
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Static magnetic fields dampen focused ultrasound-induced cavitation and blood-brain barrier opening outcome by Yang, Yaoheng, Pacia, Christopher P., Ye, Dezhuang, Yue, Yimei, Chien, Chih-Yen, Chen, Hong

“…MRI-guided focused ultrasound combined with microbubbles has been used in clinical studies for blood-brain barrier (BBB) opening. However, the impact of the…”
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Characterize brain tumor genetic signatures with focused ultrasound-enabled liquid biopsy by Pacia, Christopher P., Zhu, Lifei, Yuan, Jinyun, Yue, Yimei, Chen, Hong

“…Although blood-based liquid biopsy is a promising noninvasive diagnostic technique, the blood-brain barrier (BBB) hinders the efficient transport of brain…”
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Transcranial cavitation localization by time difference of arrival algorithm using four sensors by Hu, Zhongtao, Xu, Lu, Chien, Chih-Yen, Yang, Yaoheng, Gong, Yan, Ye, Dezhuang, Pacia, Christopher P., Chen, Hong

“…Cavitation is widely existing in focused ultrasound (FUS)-mediated therapies in the brain, such as FUS in combination with microbubble-induced blood-brain…”
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Sonobiopsy increases release of circulating tumor DNA for sensitive molecular diagnosis of glioblastoma by Pacia, Christopher P., Yuan, Jinyun, Yue, Yimei, Xu, Lu, Nazeri, Arash, Desai, Rupen, Gach, H. M., Wang, Xiaowei, Talcott, Michael, Chaudhuri, Aadel, Dunn, Gavin, Leuthardt, Eric, Chen, Hong

“…Though surgical biopsies provide direct access to tissue for genomic characterization, they are invasive and pose significant clinical risks. Brain cancer…”
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Noninvasive and cell-type specific neuromodulation by integrating ultrasound and genetics by Yang, Yaoheng, Pacia, Christopher P., Ye, Dezhuang, Zhu, Lifei, Yue, Yimei, Yuan, Jinyun, Miller, Mark, Cui, Jianmin, Joseph, Culver, Bruchas, Michael, Chen, Hong

“…The investigation of brain functions and treatment of brain disorders requires modulation of selected neurons in a noninvasive manner in the deep brain. To…”
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FUS-LBx: Focused ultrasound-enabled brain tumor liquid biopsy for noninvasive brain cancer diagnosis by Chen, Hong, Zhu, Lifei, Pacia, Christopher P., Nazeri, Arash, Yang, Yaoheng, Gach, H. Michael, Liu, Weijun, Wang, Xiaowei, Petti, Allegra, Dunn, Gavin, Leuthardt, Eric

“…Focused ultrasound (FUS) in combination with microbubbles has been studied extensively as a blood-brain barrier (BBB) disruption tool for the delivery of drugs…”
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