Search Results - "Pachuk, Catherine"

Intraoperative storage of saphenous vein grafts in coronary artery bypass grafting by Pachuk, Catherine J, Rushton-Smith, Sophie K, Emmert, Maximilian Y

“…: Saline is not biocompatible with saphenous vein grafts and does not protect against ischemia reperfusion injury. We compared normal heparinized saline with…”
Get more information

Preservation solutions to improve graft patency: The devil is in the detail by Caliskan, Etem, Pachuk, Catherine J, Perrault, Louis P, Emmert, Maximilian Y

Get full text

Vector design for liver-specific expression of multiple interfering RNAs that target hepatitis B virus transcripts by Snyder, Lindsey L., Esser, Jonathan M., Pachuk, Catherine J., Steel, Laura F.

“…RNA interference (RNAi) is a process that can target intracellular RNAs for degradation in a highly sequence-specific manner, making it a powerful tool that is…”
Get full text

Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum by Wang, Yuxin, Song, Zhili, Wagner, Janice D., Pachuk, Catherine, Subramanian, Romesh R.

“…Apolipoprotein CIII (apoCIII), a major constituent of triglyceride-rich lipoprotein, has been proposed as a key contributor to hypertriglyceridemia on the…”
Get full text

DNA Vaccines Encoding Interleukin-8 and RANTES Enhance Antigen-Specific Th1-Type CD4+ T-Cell-Mediated Protective Immunity against Herpes Simplex Virus Type 2 In Vivo by Sin, J, Kim, J J, Pachuk, C, Satishchandran, C, Weiner, D B

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Plasmid DNA—Expressed Secreted and Nonsecreted Forms of Herpes Simplex Virus Glycoprotein D2 Induce Different Types of Immune Responses by Higgins, Terry J., Herold, Kathleen M., Arnold, Renee L., McElhiney, Susan P., Shroff, Khushroo E., Pachuk, Catherine J.

“…Herpes simplex viruses (HSVs) are significant pathogens and major targets of vaccine development. Several attempts have been made to develop prophylactic and…”
Get full text

A spectrophotometric method to quantify linear DNA by Samuel, Manoj, Lu, Meiqing, Pachuk, Catherine J, Satishchandran, C

“…A spectrophotometric method for quantification of linear DNA is described. The assay measures ADP produced following digestion of linear DNA by an…”
Get full text

Characterization of a new class of DNA delivery complexes formed by the local anesthetic bupivacaine by Pachuk, Catherine J, Ciccarelli, Richard B, Samuel, Manoj, Bayer, Manfred E, Troutman, Robert D, Zurawski, Daniel V, Schauer, Julia I, Higgins, Terry J, Weiner, David B, Sosnoski, Donna M, Zurawski, Vincent R, Satishchandran, C

“…Bupivacaine, a local anesthetic and cationic amphiphile, forms stable liposomal-like structures upon direct mixing with plasmid DNA in aqueous solutions. These…”
Get full text

The primary structure and expression of the second open reading frame of the polymerase gene of the coronavirus MHV-A59; a highly conserved polymerase is expressed by an efficient ribosomal frameshifting mechanism by Bredenbeek, P J, Pachuk, C J, Noten, A F, Charité, J, Luytjes, W, Weiss, S R, Spaan, W J

“…Sequence analysis of a substantial part of the polymerase gene of the murine coronavirus MHV-A59 revealed the 3' end of an open reading frame (ORF1a)…”
Get full text

RNA interference and its potential applications to chronic HBV treatment: results of a Phase I safety and tolerability study by Gish, Robert G, Satishchandran, C, Young, Michael, Pachuk, Catherine

“…RNA interference (RNAi) provides an attractive tool to modulate biological systems, and ultimately, to treat human diseases. We describe early results from a…”
Get more information

Molecular cloning of the gene encoding the putative polymerase of mouse hepatitis coronavirus, strain A59 by Pachuk, C J, Bredenbeek, P J, Zoltick, P W, Spaan, W J, Weiss, S R

“…Complementary DNA (cDNA) libraries were constructed representing the genome RNA of the coronavirus mouse hepatitis virus, strain A59 (MHV-A59). From these…”
Get more information

Abstract 1646: In vivo target validation in orthotopic hepatocellular carcinoma model using formulated siRNA by Liao, Baisong, Kellner, Debra, Wang, Chunrong, Wu, Shilu, Molina, Marion, Zhu, De-Min, Gollerkeri, Ashwin, Pachuk, Catherine

“…Abstract Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and its incidence continues to increase. Although there are approved…”
Get full text

Expression and immune response to hepatitis C virus core DNA-based vaccine constructs by Tokushige, K, Wakita, T, Pachuk, C, Moradpour, D, Weiner, DB, Zurawski, VR, Wands, JR

“…Hepatitis C virus (HCV) is a major worldwide cause of acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The development of vaccines against…”
Get full text

DNA priming-protein boosting enhances both antigen-specific antibody and Th1-type cellular immune responses in a murine herpes simplex virus-2 gD vaccine model by Sin, J I, Bagarazzi, M, Pachuk, C, Weiner, D B

“…It has previously been reported that herpes simplex virus (HSV)-2 gD DNA vaccine preferentially induces T-helper (Th) 1-type cellular immune responses, whereas…”
Get more information

Chain reaction cloning: a one-step method for directional ligation of multiple DNA fragments by Pachuk, Catherine J., Samuel, Manoj, Zurawski, John A., Snyder, Linda, Phillips, Paula, Satishchandran, C.

“…A novel DNA assembly method, chain reaction cloning (CRC), is described. CRC enables the ordered assembly of multiple DNA fragments in a single step. The power…”
Get full text

Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences by Pachuk, Catherine, Yoon, Kyonggeun, Moelling, Karin, Coney, Leslie R.

“…Conventionally designed ribozymes may be unable to cleave RNA at sites which are inaccessible due to secondary structure. In addition, it may also be difficult…”
Get full text

Methods for DNA introduction into mammalian cells by Norton, Pamela A., Pachuk, Catherine J.

“…The development of methods for the introduction of DNA into cultured cells, especially mammalian cells, has proceeded in parallel with advances in molecular…”
Get full text

Facilitated DNA inoculation induces anti-HIV-1 immunity in vivo by Coney, L, Wang, B, Ugen, K E, Boyer, J, McCallus, D, Srikantan, V, Agadjanyan, M, Pachuk, C J, Herold, K, Merva, M

“…Vaccine design against HIV-1 is complicated both by the latent aspects of lentiviral infection and the diversity of the virus. The type of vaccine approach…”
Get more information

Identification of polypeptides encoded in open reading frame 1b of the putative polymerase gene of the murine coronavirus mouse hepatitis virus A59 by DENISON, M. R, ZOLTICK, P. W, LEIBOWITZ, J. L, PACHUK, C. J, WEISS, S. R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

DNA vaccines--challenges in delivery by Pachuk, C J, McCallus, D E, Weiner, D B, Satishchandran, C

“…DNA vaccines are typically comprised of plasmid DNA molecules that encode an antigen(s) derived from a pathogen or tumor cell. Following introduction into a…”
Get more information