Search Results - "Pachon, Angelica"
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Sex Difference Leads to Differential Gene Expression Patterns and Therapeutic Efficacy in Mucopolysaccharidosis IVA Murine Model Receiving AAV8 Gene Therapy
Published in International journal of molecular sciences (21-10-2022)“…Adeno-associated virus (AAV) vector-based therapies can effectively correct some disease pathology in murine models with mucopolysaccharidoses. However,…”
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2
Current Strategies for Increasing Knock-In Efficiency in CRISPR/Cas9-Based Approaches
Published in International journal of molecular sciences (20-02-2024)“…Since its discovery in 2012, the clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) system has supposed…”
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3
The landscape of CRISPR/Cas9 for inborn errors of metabolism
Published in Molecular genetics and metabolism (01-01-2023)“…Since its discovery as a genome editing tool, the clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR/Cas9)…”
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4
DNA approach to scenery reconstruction
Published in Stochastic processes and their applications (01-11-2011)“…The basic reconstruction problem lead with the general task of retrieving a scenery from observations made by a random walker. A critical factor associated…”
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Scale-free behavior of networks with the copresence of preferential and uniform attachment rules
Published in Physica. D (15-05-2018)“…Complex networks in different areas exhibit degree distributions with a heavy upper tail. A preferential attachment mechanism in a growth process produces a…”
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On the continuous-time limit of the Barabási–Albert random graph
Published in Applied mathematics and computation (01-08-2020)“…•Relationships between Barabàsi–Albert random graph and Yule model are studied.•Continuous-time macroevolutionary models as limits of Barabàsi–Albert…”
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Cost‐utility analysis of an integrated care program for children with asthma in a medium‐income country
Published in Pediatric pulmonology (01-11-2020)“…Objective To evaluate the cost‐utility of an integrated care program (ASMAIRE Infantil Program [PAI]) for children with asthma compared with standard of care…”
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Random Graphs Associated to Some Discrete and Continuous Time Preferential Attachment Models
Published in Journal of statistical physics (01-03-2016)“…We give a common description of Simon, Barabási–Albert, II-PA and Price growth models, by introducing suitable random graph processes with preferential…”
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Phase Transition for the Maki–Thompson Rumour Model on a Small-World Network
Published in Journal of statistical physics (01-11-2017)“…We consider the Maki–Thompson model for the stochastic propagation of a rumour within a population. In this model the population is made up of “spreaders”,…”
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10
RECONSTRUCTION OF A MULTIDIMENSIONAL SCENERY WITH A BRANCHING RANDOM WALK
Published in The Annals of applied probability (01-04-2017)“…We consider a d-dimensional scenery seen along a simple symmetric branching random walk, where at each time each particle gives the color record it observes…”
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11
Evolution of a Modified Binomial Random Graph by Agglomeration
Published in Journal of statistical physics (01-02-2018)“…In the classical Erdős–Rényi random graph G ( n , p ) there are n vertices and each of the possible edges is independently present with probability p . The…”
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12
Phase transition in preferential attachment-detachment through embedding
Published 13-10-2024“…We study a random graph model with preferential edge attachment and detachment through the embedding into a generalized Yule model. We show that the in-degree…”
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13
Mucopolysaccharidoses: Cellular Consequences of Glycosaminoglycans Accumulation and Potential Targets
Published in International journal of molecular sciences (28-12-2022)“…Mucopolysaccharidoses (MPSs) constitute a heterogeneous group of lysosomal storage disorders characterized by the lysosomal accumulation of glycosaminoglycans…”
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14
Bone Growth Induction in Mucopolysaccharidosis IVA Mouse
Published in International journal of molecular sciences (01-06-2023)“…Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is caused by a deficiency of the N-acetylgalactosamine-6-sulfate-sulfatase (GALNS) enzyme, leading to…”
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15
Scenery reconstruction with branching random walk
Published in Stochastics (Abingdon, Eng. : 2005) (01-04-2011)“…We study the problem of scenery reconstruction in arbitrary dimension using observations registered in boxes of size k (for k fixed), seen along a branching…”
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Adeno-associated virus-based gene therapy delivering combinations of two growth-associated genes to MPS IVA mice
Published in Molecular therapy. Nucleic acids (11-06-2024)“…Mucopolysaccharidosis type IVA (MPS IVA) is caused by a deficiency of the galactosamine (N-acetyl)-6-sulfatase (GALNS) enzyme responsible for the degradation…”
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State of the art about metaheuristics and artificial neural networks applied to open pit mining
Published in Resources policy (01-03-2019)“…In search of the best way to extract and take advantage of minerals, highlighting that these are part of the most important raw materials for the economic…”
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18
Upper bounds for the largest components in critical inhomogeneous random graphs
Published 16-12-2020“…We consider the Norros-Reittu random graph $NR_n(\textbf{w})$, where edges are present independently but edge probabilities are moderated by vertex weights,…”
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On discrete-time semi-Markov processes
Published 20-07-2018“…In the last years, many authors studied a class of continuous time semi-Markov processes obtained by time-changing Markov processes by hitting times of…”
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20
Scale-free behavior of networks with the copresence of preferential and uniform attachment rules
Published 27-04-2017“…Complex networks in different areas exhibit degree distributions with heavy upper tail. A preferential attachment mechanism in a growth process produces a…”
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