Search Results - "Pachón, Jerónimo"

Acinetobacter baumannii: human infections, factors contributing to pathogenesis and animal models by McConnell, Michael J., Actis, Luis, Pachón, Jerónimo

“…Abstract Acinetobacter baumannii has emerged as a medically important pathogen because of the increasing number of infections produced by this organism over…”
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Perspectives for clinical use of engineered human host defense antimicrobial peptides by Pachón-Ibáñez, María Eugenia, Smani, Younes, Pachón, Jerónimo, Sánchez-Céspedes, Javier

“…Abstract Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of death worldwide. The emergence of drug-resistance mechanisms,…”
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Structure–Activity Relationship Studies on Diversified Salicylamide Derivatives as Potent Inhibitors of Human Adenovirus Infection by Xu, Jimin, Berastegui-Cabrera, Judith, Chen, Haiying, Pachón, Jerónimo, Zhou, Jia, Sánchez-Céspedes, Javier

“…The effective treatment of adenovirus (HAdV) infections in immunocompromised patients still poses great challenges. Herein, we reported our continued efforts…”
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Role of fibronectin in the adhesion of Acinetobacter baumannii to host cells by Smani, Younes, McConnell, Michael J, Pachón, Jerónimo

“…Adhesion to host cells is an initial and important step in Acinetobacter baumannii pathogenesis. However, there is relatively little information on the…”
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Repositioning salicylanilide anthelmintic drugs to treat adenovirus infections by Marrugal-Lorenzo, José A., Serna-Gallego, Ana, Berastegui-Cabrera, Judith, Pachón, Jerónimo, Sánchez-Céspedes, Javier

“…The repositioning of drugs already approved by regulatory agencies for other indications is an emerging alternative for the development of new antimicrobial…”
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iTRAQ-Based Quantitative Proteomic Analysis of Acinetobacter baumannii under Hypoxia and Normoxia Reveals the Role of OmpW as a Virulence Factor by Gil-Marqués, María Luisa, Pachón, Jerónimo, Smani, Younes

“…Acinetobacter baumannii needs to adapt to hypoxia during infection. Understanding its proteome regulation during infection would allow us to determine new…”
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Excretion and viability of SARS-CoV-2 in feces and its association with the clinical outcome of COVID-19 by Cerrada-Romero, Cristina, Berastegui-Cabrera, Judith, Camacho-Martínez, Pedro, Goikoetxea-Aguirre, Josune, Pérez-Palacios, Patricia, Santibáñez, Sonia, José Blanco-Vidal, María, Valiente, Adoración, Alba, Jorge, Rodríguez-Álvarez, Regino, Pascual, Álvaro, Oteo, José Antonio, Miguel Cisneros, José, Pachón, Jerónimo, Casas-Flecha, Inmaculada, Cordero, Elisa, Pozo, Francisco, Sánchez-Céspedes, Javier

“…The main objective was to evaluate the viability of the SARS-CoV-2 viral particles excreted in stools. In addition, we aimed to identify clinical factors…”
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Therapeutic efficacy of lysophosphatidylcholine in severe infections caused by Acinetobacter baumannii by Smani, Younes, Domínguez-Herrera, Juan, Ibáñez-Martínez, José, Pachón, Jerónimo

“…Due to the significant increase in antimicrobial resistance of Acinetobacter baumannii, immune system stimulation to block infection progression may be a…”
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New 4‑Acyl-1-phenylaminocarbonyl-2-phenylpiperazine Derivatives as Potential Inhibitors of Adenovirus Infection. Synthesis, Biological Evaluation, and Structure–activity Relationships by Sánchez-Céspedes, Javier, Martínez-Aguado, Pablo, Vega-Holm, Margarita, Serna-Gallego, Ana, Candela, José Ignacio, Marrugal-Lorenzo, José Antonio, Pachón, Jerónimo, Iglesias-Guerra, Fernando, Vega-Pérez, José Manuel

“…The search for human adenovirus (HAdV)-specific antiviral drugs for the treatment of HAdV infections in immunocompromised patients continues to be a…”
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Discovery of Novel Substituted N‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Xu, Jimin, Berastegui-Cabrera, Judith, Ye, Na, Carretero-Ledesma, Marta, Pachón-Díaz, Jerónimo, Chen, Haiying, Pachón-Ibáñez, Maria Eugenia, Sánchez-Céspedes, Javier, Zhou, Jia

“…An effective therapy for human adenovirus (HAdV) infections in immunocompromised patients and healthy individuals with community-acquired pneumonia remains an…”
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Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB by Parra-Millán, Raquel, Guerrero-Gómez, David, Ayerbe-Algaba, Rafael, Pachón-Ibáñez, Maria Eugenia, Miranda-Vizuete, Antonio, Pachón, Jerónimo, Smani, Younes

“…Acinetobacter baumannii is a significant human pathogen associated with hospital-acquired infections. While adhesion, an initial and important step in…”
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Activity of Tigecycline (GAR-936) against Acinetobacter baumannii Strains, Including Those Resistant to Imipenem by Pachón-Ibáñez, María Eugenia, Jiménez-Mejías, Manuel Enrique, Pichardo, Cristina, Llanos, Ana Cristina, Pachón, Jerónimo

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Three-year multicenter surveillance of community-acquired Listeria monocytogenes meningitis in adults by Amaya-Villar, Rosario, García-Cabrera, Emilio, Sulleiro-Igual, Elena, Fernández-Viladrich, Pedro, Fontanals-Aymerich, Dionisi, Catalán-Alonso, Pilar, Rodrigo-Gonzalo de Liria, Carlos, Coloma-Conde, Ana, Grill-Díaz, Fabio, Guerrero-Espejo, Antonio, Pachón, Jerónimo, Prats-Pastor, Guillén

“…Listeria monocytogenes is the third most frequent cause of bacterial meningitis. The aim of this study is to know the incidence and risk factors associated…”
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Serinol-Based Benzoic Acid Esters as New Scaffolds for the Development of Adenovirus Infection Inhibitors: Design, Synthesis, and In Vitro Biological Evaluation by Mazzotta, Sarah, Berastegui-Cabrera, Judith, Carullo, Gabriele, Vega-Holm, Margarita, Carretero-Ledesma, Marta, Mendolia, Lara, Aiello, Francesca, Iglesias-Guerra, Fernando, Pachón, Jerónimo, Vega-Pérez, José Manuel, Sánchez-Céspedes, Javier

“…Over the years, human adenovirus (HAdV) has progressively been recognized as a significant viral pathogen. Traditionally associated with self-limited…”
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T-cells immune response controls the high incidence of adenovirus infection in adult allogenic hematopoietic transplantation recipients by Sánchez-Céspedes, Javier, Marrugal-Lorenzo, José Antonio, Martín-Gandul, Cecilia, Rodríguez-Torres, Nancy, Montero-Mateos, Enrique, Serna-Gallego, Ana, Escamilla-Gómez, Virginia, Merino, Laura, Espigado, Ildefonso, Pachón, Jerónimo, Pérez-Simón, José Antonio, Aguilar-Guisado, Manuela

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Role of OmpA in the Multidrug Resistance Phenotype of Acinetobacter baumannii by SMANI, Younes, FABREGA, Anna, ROCA, Ignasi, SANCHEZ-ENCINALES, Viviana, VILA, Jordi, PACHON, Jerónimo

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Outer membrane vesicles as an acellular vaccine against Acinetobacter baumannii by McConnell, Michael J, Rumbo, Carlos, Bou, Germán, Pachón, Jerónimo

“…Highlights ► Acinetobacter baumannii produces OMVs that contain immunogenic outer membrane proteins. ► Immunization of mice with A. baumannii OMVs produces a…”
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Association of the Outer Membrane Protein Omp33 With Fitness and Virulence of Acinetobacter baumannii by Smani, Younes, Dominguez-Herrera, Juan, Pachón, Jerónimo

“…Outer membrane protein 33 (Omp33) is an outer membrane porin of Acinetobacter baumannii associated with carbapenem resistance. However, the role of Omp33 in…”
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Role of Acinetobactin-Mediated Iron Acquisition Functions in the Interaction of Acinetobacter baumannii Strain ATCC 19606T with Human Lung Epithelial Cells, Galleria mellonella Caterpillars, and Mice by GADDY, Jennifer A, ARIVETT, Brock A, MCCONNELL, Michael J, LOPEZ-ROJAS, Rafael, PACHON, Jerónimo, ACTIS, Luis A

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Vaccination with Outer Membrane Complexes Elicits Rapid Protective Immunity to Multidrug-Resistant Acinetobacter baumannii by McConnell, Michael J, Domínguez-Herrera, Juan, Smani, Younes, López-Rojas, Rafael, Docobo-Pérez, Fernando, Pachón, Jerónimo

“…Acinetobacter baumannii causes pneumonias, bacteremias, and skin and soft tissue infections, primarily in the hospitalized setting. The incidence of infections…”
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