Search Results - "Pace, Edward"
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Abnormal dynamic functional connectivity during fear extinction learning in PTSD and anxiety disorders
Published in Molecular psychiatry (01-04-2022)“…Examining the neural circuits of fear/threat extinction advanced our mechanistic understanding of several psychiatric disorders, including anxiety disorders…”
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Multiverse analyses of fear acquisition and extinction retention in posttraumatic stress disorder
Published in Psychophysiology (01-07-2023)“…Persistent fear is a cardinal feature of posttraumatic stress disorder (PTSD), and deficient fear extinction retention is a proposed illness mechanism and…”
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Noise-induced tinnitus using individualized gap detection analysis and its relationship with hyperacusis, anxiety, and spatial cognition
Published in PloS one (12-09-2013)“…Tinnitus has a complex etiology that involves auditory and non-auditory factors and may be accompanied by hyperacusis, anxiety and cognitive changes. Thus far,…”
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Processing of emotional reactivity and emotional memory over sleep
Published in The Journal of neuroscience (18-01-2012)“…Sleep enhances memories, particularly emotional memories. As such, it has been suggested that sleep deprivation may reduce posttraumatic stress disorder. This…”
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Blast-induced tinnitus and hyperactivity in the auditory cortex of rats
Published in Neuroscience (06-01-2017)“…Highlights • Blast induces delayed increases in spontaneous firing in the auditory cortex of rats with tinnitus. • Blast induces delayed increases in bursting…”
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Neuroinflammation mediates noise-induced synaptic imbalance and tinnitus in rodent models
Published in PLoS biology (18-06-2019)“…Hearing loss is a major risk factor for tinnitus, hyperacusis, and central auditory processing disorder. Although recent studies indicate that hearing loss…”
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Autonomic activity, posttraumatic and nontraumatic nightmares, and PTSD after trauma exposure
Published in Psychological medicine (01-02-2023)“…Nightmares are a hallmark symptom of posttraumatic stress disorder (PTSD). This strong association may reflect a shared pathophysiology in the form of altered…”
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Time course of blast-induced injury in the rat auditory cortex
Published in PloS one (28-02-2018)“…Blast exposure is an increasingly significant health hazard and can have a range of debilitating effects, including auditory dysfunction and traumatic brain…”
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The influence of sleep on fear extinction in trauma-related disorders
Published in Neurobiology of stress (01-01-2023)“…In Posttraumatic Stress Disorder (PTSD), fear and anxiety become dysregulated following psychologically traumatic events. Regulation of fear and anxiety…”
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Morning blue light treatment improves sleep complaints, symptom severity, and retention of fear extinction memory in post-traumatic stress disorder
Published in Frontiers in behavioral neuroscience (12-09-2022)“…Disrupted sleep is a major feature in numerous clinical disorders and is related to decrements in affective memory processing. The prevalence of sleep…”
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Call to action: Addressing sleep disturbances, a hallmark symptom of PTSD, for refugees, asylum seekers, and internally displaced persons
Published in Sleep health (01-12-2022)“…Sleep difficulty is a recognized hallmark symptom of post-traumatic stress disorder (PTSD) yet often remains an enduring and neglected problem post-treatment…”
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Contribution of estradiol levels and hormonal contraceptives to sex differences within the fear network during fear conditioning and extinction
Published in BMC psychiatry (18-11-2015)“…Findings about sex differences in the field of fear conditioning and fear extinction have been mixed. At the psychophysiological level, sex differences emerge…”
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Editorial: How does sleep help regulate negative emotion?
Published in Frontiers in behavioral neuroscience (09-01-2023)“…The stimuli are typically presented during slow wave sleep (SWS) during which the influential active systems consolidation model (Klinzing et al., 2019)…”
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Interaction of sleep and emotional content on the production of false memories
Published in PloS one (07-11-2012)“…Sleep benefits veridical memories, resulting in superior recall relative to off-line intervals spent awake. Sleep also increases false memory recall in the…”
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Distributed neural representations of conditioned threat in the human brain
Published in Nature communications (12-03-2024)“…Detecting and responding to threat engages several neural nodes including the amygdala, hippocampus, insular cortex, and medial prefrontal cortices. Recent…”
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A Conditioned Behavioral Paradigm for Assessing Onset and Lasting Tinnitus in Rats
Published in PloS one (11-11-2016)“…Numerous behavioral paradigms have been developed to assess tinnitus-like behavior in animals. Nevertheless, they are often limited by prolonged training…”
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The Neurobiology of Sleep: Genetics, cellular physiology and subcortical networks
Published in Nature reviews. Neuroscience (01-08-2002)“…To appreciate the neural underpinnings of sleep, it is important to view this universal mammalian behaviour at multiple levels of its biological organization…”
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Blast-Induced Tinnitus and Elevated Central Auditory and Limbic Activity in Rats: A Manganese-Enhanced MRI and Behavioral Study
Published in Scientific reports (07-07-2017)“…Blast-induced tinitus is the number one service-connected disability that currently affects military personnel and veterans. To elucidate its underlying…”
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Rapid eye movement sleep parasympathetic activity predicts wake hyperarousal symptoms following a traumatic event
Published in Journal of sleep research (01-02-2023)“…Summary Heart rate variability (HRV) can be used to assess changes in output of the parasympathetic nervous system (PNS). Considering that patients with…”
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