Search Results - "Pacchierotti, F."

Environmental hazard in the aetiology of somatic and germ cell aneuploidy by Pacchierotti, F, Eichenlaub-Ritter, U

“…Sources of environmental exposures to potentially aneugenic agents are many and include occupational and therapeutic exposures, and exposures associated with…”
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Evaluation of aneugenic effects of bisphenol A in somatic and germ cells of the mouse by Pacchierotti, F., Ranaldi, R., Eichenlaub-Ritter, U., Attia, S., Adler, I.-D.

“…Bisphenol A (BPA) is a synthetic monomer widely used to polymerize polycarbonate plastics and resins. It is shown in vitro to interfere with microtubules,…”
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Gender effects on the incidence of aneuploidy in mammalian germ cells by Pacchierotti, F., Adler, I.-D., Eichenlaub-Ritter, U., Mailhes, J.B.

“…Aneuploidy occurs in 0.3% of newborns, 4% of stillbirths, and more than 35% of all human spontaneous abortions. Human gametogenesis is uniquely and…”
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Effect of p53 haploinsufficiency on melphalan-induced genotoxic effects in mouse bone marrow and peripheral blood by Ranaldi, R, Palma, S, Tanzarella, C, Lascialfari, A, Cinelli, S, Pacchierotti, F

“…Mice heterozygous for a p53 null mutation develop tumours induced by genotoxic carcinogens with a shorter latency than wild type mice and have been proposed as…”
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Griseofulvin induces mitotic delay and aneuploidy in bone marrow cells of orally treated mice by Pacchierotti, Francesca, Bassani, Bruno, Marchetti, Francesco, Tiveron, Cecilia

“…Griseofulvin (GF) is a fungicide drug well characterized for its aneugenic activity in vitro. In vivo strong evidence of aneuploidy and polyploidy induction…”
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Nondisjunction rates of mouse chromosomes involved in heterozygous Rb rearrangements measured by chromosome painting of spermatocytes. II. The effects of trivalent combinations and genetic background by Scascitelli, M, Gustavino, B, Pacchierotti, F, Spirito, F, Rizzoni, M

“…Chromosome specific nondisjunction rates were quantified by dual-colour FISH in spermatocytes II of Robertsonian heterozygous mice with different trivalent…”
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Nondisjunction rates of mouse specific chromosomes involved in heterozygous Rb rearrangements measured by chromosome painting of spermatocytes II. I. The effects of the number of trivalents by Scascitelli, M, Gustavino, B, Pacchierotti, F, Spirito, F, Rizzoni, M

“…Dual-colour FISH painting with alternative fluorescent chromosome-specific probes allowed us to distinguish chromosomes 1, 4, 6 and 14. The purpose was to…”
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Cosegregation of Robertsonian metacentric chromosomes in the first meiotic division of multiple heterozygous male mice as revealed by FISH analysis of spermatocyte II metaphases by Scascitelli, M, Pacchierotti, F, Rizzoni, M, Gustavino, B, Spirito, F

“…Contrasting results (random segregation or cosegregation of isomorphic chromosomes) have been reported up to now on the segregation pattern of Robertsonian…”
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Analysis of micronuclei and DNA single-strand breaks in mouse splenocytes and peripheral lymphocytes after oral administration of tetramethylthiuram disulfide (Thiram) by Villani, P., Andreoli, C., Crebelli, R., Pacchierotti, F., Zijno, A., Carere, A.

“…The fungicide thiram (tetramethylthiuram disulfide, TMTD) was administered by repeated oral intubations to groups of male B6C3F 1 mice at 100, 300 and 900…”
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Cytogenetic biomonitoring of workers from laboratories of clinical analyses occupationally exposed to chemicals by Testa, A, Ranaldi, R, Carpineto, L, Pacchierotti, F, Tirindelli, D, Fabiani, L, Giuliani, A.R, Urso, M, Rossini, A, Materazzo, F, Petyx, M, Leoni, V

“…A cytogenetic monitoring study was carried out on a group of workers in clinical analysis laboratories to investigate the risk of occupational exposure to…”
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Exposure of mouse oocytes to bisphenol A causes meiotic arrest but not aneuploidy by Eichenlaub-Ritter, Ursula, Vogt, Edgar, Cukurcam, Suna, Sun, Fengyun, Pacchierotti, Francesca, Parry, Jim

“…Mouse oocytes isolated from large antral follicles were exposed to a wide range of concentrations of bisphenol A (BPA) during maturation in vitro (50 ng/ml to…”
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Biodistribution and acute toxicity of a nanofluid containing manganese iron oxide nanoparticles produced by a mechanochemical process by Bellusci, Mariangela, La Barbera, Aurelio, Padella, Franco, Mancuso, Mariateresa, Pasquo, Alessandra, Grollino, Maria Giuseppa, Leter, Giorgio, Nardi, Elisa, Cremisini, Carlo, Giardullo, Paola, Pacchierotti, Francesca

“…Superparamagnetic iron oxide nanoparticles are candidate contrast agents for magnetic resonance imaging and targeted drug delivery. Biodistribution and…”
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Clastogenicity of diepoxybutane in bone marrow cells and male germ cells of mice by Adler, I D, Kliesch, U, Tiveron, C, Pacchierotti, F

“…The bifunctional metabolite of 1,3-butadiene, 1,2:3,4-diepoxybutane (DEB), was tested in the mouse bone marrow micronucleus assay and in male mouse germ cell…”
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Induction and transmission of chromosome aberrations in mouse oocytes after treatment with butadiene diepoxide by Tiveron, C., Ranaldi, R., Bassani, B., Pacchierotti, F.

“…A study was conducted on the genotoxicity of butadiene diepoxide (DEB) in mouse oocytes. Superovulated female mice were injected intraperitoneally with DEB and…”
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In vivo repair of DNA damage induced by X-rays in the early stages of mouse fertilization, and the influence of maternal PARP1 ablation by Pacchierotti, F, Ranaldi, R, Derijck, A A, van der Heijden, G W, de Boer, P

“…The early pronucleus stage of the mouse zygote has been characterised in vitro as radiosensitive, due to a high rate of induction of chromosome-type chromosome…”
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Noscapine does not show aneugenic activity in mouse oocytes by Tiveron, C, Hartley-Asp, B, Johansson, C J, Pacchierotti, F

“…To clarify if noscapine has the ability to induce polyploidy in rodent germ cells in vivo, a cytogenetic study of mouse metaphase II oocytes was conducted…”
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Glutathione depletion enhances germ cell toxicity of butadiene metabolites: a flow cytometric study by Cordelli, E, Leter, G, Pacchierotti, F, Tiveron, C, Spanò, M

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Nitrilotriacetic acid (NTA) induces aneuploidy in Drosophila and mouse germ-line cells by Costa, R, Russo, A, Zordan, M, Pacchierotti, F, Tavella, A, Levis, A G

“…The ability of nitrilotriacetic acid (NTA) to induce aneuploidy was studied in the germ line of both Drosophila and the mouse. The Free Inverted X Chromosomes…”
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Aneuploidy dose-responses following radiation or chemical exposures in mammals by Pacchierotti, F, Mailhes, J B

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Trichlorfon effects on mouse oocytes following in vivo exposure by Ranaldi, Roberto, Gambuti, Gloria, Eichenlaub-Ritter, Ursula, Pacchierotti, Francesca

“…Trichlorfon (TCF) is a widely used pesticide, which according to some epidemiological and experimental data, is suspected of being aneugenic in human and mouse…”
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