Search Results - "Pabst, M."

Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics by Pabst, Timothy M., Thai, Johnny, Hunter, Alan K.

“…•12 Protein A stationary phases were compared using nine Fc-containing proteins.•Morphological properties were investigated using four orthogonal…”
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Adaptation of anammox bacteria to low temperature via gradual acclimation and cold shocks: Distinctions in protein expression, membrane composition and activities by V, Kouba, D, Vejmelkova, E, Zwolsman, K, Hurkova, K, Navratilova, M, Laureni, P, Vodickova, T, Podzimek, J, Hajslova, M, Pabst, MCM, van Loosdrecht, J, Bartacek, P, Lipovova, DG, Weissbrodt

“…•Anammox bacteria were adapted to low t by gradual acclimation and cold shocks.•The shocked culture was more active than gradually acclimated…”
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Clinical Use of PET/MR in Oncology: An Update by Seifert, Robert, Kersting, David, Rischpler, Christoph, Opitz, Marcel, Kirchner, Julian, Pabst, Kim M., Mavroeidi, Ilektra-Antonia, Laschinsky, Christina, Grueneisen, Johannes, Schaarschmidt, Benedikt, Catalano, Onofrio Antonio, Herrmann, Ken, Umutlu, Lale

“…The combination of PET and MRI is one of the recent advances of hybrid imaging. Yet to date, the adoption rate of PET/MRI systems has been rather slow. This…”
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Adsorption equilibrium and kinetics of monomer–dimer monoclonal antibody mixtures on a cation exchange resin by Reck, Jason M., Pabst, Timothy M., Hunter, Alan K., Wang, Xiangyang, Carta, Giorgio

“…•Adsorption of mAb monomer/dimer mixtures on CEX resin visualized by CLSM.•Monomer/dimer selectivity varies with salt concentration.•Displacement of monomer by…”
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Exploring the role of antimicrobials in the selective growth of purple phototrophic bacteria through genome mining and agar spot assays by Alloul, A., Van Kampen, W., Cerruti, M., Wittouck, S., Pabst, M., Weissbrodt, D.G.

“…Purple non‐sulphur bacteria (PNSB) are an emerging group of microbes attractive for applied microbiology applications such as wastewater treatment, plant…”
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Impact of constant storage temperatures and multiple warming cycles on the quality of stored red blood cells by Wagner, T., Pabst, M.-A., Leitinger, G., Reiter, U., Kozma, N., Lanzer, G., Huppertz, B.

“…Background Red blood cells (RBCs) are routinely stored in liquid state at temperatures below 6°C, and RBC unit core temperature should not exceed 10°C during…”
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Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity by Pabst, Timothy M., Palmgren, Ronnie, Forss, Annika, Vasic, Jelena, Fonseca, Mariko, Thompson, Christopher, Wang, William K., Wang, Xiangyang, Hunter, Alan K.

“…•Two novel Protein A ligands are described that enable elution at milder pH.•The ligands are coupled to a support matrix and tested against a panel of…”
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Influence of mechanical compression on human periodontal ligament fibroblasts and osteoblasts by Nettelhoff, L., Grimm, S., Jacobs, C., Walter, C., Pabst, A. M., Goldschmitt, J., Wehrbein, H.

“…Objectives The aim of this study was to investigate and compare the changes in human periodontal ligament fibroblasts (HPdLFs) and osteoblasts (HOBs) after the…”
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Photochemical regeneration of flavoenzymes – An Old Yellow Enzyme case-study by Rauch, M.C.R., Huijbers, M.M.E., Pabst, M., Paul, C.E., Pešić, M., Arends, I.W.C.E., Hollmann, F.

“…Direct, NAD(P)H-independent regeneration of Old Yellow Enzymes represents an interesting approach for simplified reaction schemes for the stereoselective…”
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[68Ga]Ga-FAPI versus 2-[18F]FDG PET/CT in patients with autoimmune thyroiditis: a case control study by Pabst, Kim M., Kessler, Lukas, Ferdinandus, Justin, Hamacher, Rainer, Bartel, Timo, Siveke, Jens T., Nader, Michael, Brandenburg, Tim, Desaulniers, Mélanie, Herrmann, Ken, Fendler, Wolfgang P.

“…Purpose Radiolabelled fibroblast activation protein inhibitors (FAPIs) are becoming increasingly important for imaging various tumour diseases. However, it is…”
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In vitro and in vivo characterization of porcine acellular dermal matrix for gingival augmentation procedures by Pabst, A. M., Happe, A., Callaway, A., Ziebart, T., Stratul, S. I., Ackermann, M., Konerding, M. A., Willershausen, B., Kasaj, A.

“…Background and Objective Recently, porcine acellular dermal matrix (PADM) has been proposed as a possible alternative to autogenous grafts in periodontal…”
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pH transitions in cation exchange chromatographic columns containing weak acid groups by Pabst, Timothy M., Carta, Giorgio

“…Complex pH transitions occur in cation exchange columns used for protein chromatography during equilibration and salt elution steps when the stationary phase…”
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The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes—in vitro study by Pabst, Andreas M., Ziebart, Thomas, Koch, Felix P., Taylor, Katherine Y., Al-Nawas, Bilal, Walter, Christian

“…Bisphosphonate-associated osteonecrosis of the jaw (BP-ONJ) is one of the most often seen side effects in patients treated with bisphosphonates, presenting…”
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Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine by Weber, Patrick, Thonhofer, Martin, Averill, Summer, Davies, Gideon J, Santana, Andres Gonzalez, Müller, Philipp, Nasseri, Seyed A, Offen, Wendy A, Pabst, Bettina M, Paschke, Eduard, Schalli, Michael, Torvisco, Ana, Tschernutter, Marion, Tysoe, Christina, Windischhofer, Werner, Withers, Stephen G, Wolfsgruber, Andreas, Wrodnigg, Tanja M, Stütz, Arnold E

“…Glycosidase inhibitors have shown great potential as pharmacological chaperones for lysosomal storage diseases. In light of this, a series of new…”
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Improved analysis of ultra-high molecular mass polystyrenes in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using DCTB matrix and caesium salts by Gabriel, S. J., Steinhoff, R. F., Pabst, M., Schwarzinger, C., Zenobi, R., Panne, U., Weidner, S. M.

“…Rationale The ionization of polystyrenes in matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) is typically achieved by the use of silver…”
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Bisphosphonates inhibit cell functions of HUVECs, fibroblasts and osteogenic cells via inhibition of protein geranylgeranylation by Hagelauer, Nadine, Ziebart, Thomas, Pabst, Andreas M., Walter, Christian

“…Objectives Bisphosphonate-associated osteonecrosis of the jaw is a severe side effect in patients receiving nitrogen-containing bisphosphonates (N-BPs). One…”
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Effect of a colorectal bundle in an entire health care region in Switzerland: Results from a prospective cohort study (EvaCol study) by Wiesler, B, Rosenberg, R, Galli, R, Metzger, J, Worni, M, Henschel, M, Hartel, M, Nebiker, C, Viehl, C T, Müller, A, Eisner, L, Pabst, M, Zingg, U, Stimpfle, D, Müller, B, von Flüe, M, Peterli, R, Werlen, L, Zuber, M, Gass, J-M, von Strauss Und Torney, M

“…Standardisation has the potential to serve as a measure to mitigate complication rates. The objective was to assess the impact of standardisation by…”
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Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation by Luo, Haibin, Tie, Liu, Cao, Mingyan, Hunter, Alan K., Pabst, Timothy M., Du, Jiali, Field, Raymond, Li, Yuling, Wang, William K.

“…A stochastic approach of copurification of the protease Cathepsin L that results in product fragmentation during purification processing and storage is…”
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Protein Mass Transfer Kinetics in Ion Exchange Media: Measurements and Interpretations by Carta, G., Ubiera, A. R., Pabst, T. M.

“…The paper gives a summary of successful methods for measuring protein mass transfer kinetics in ion exchange matrices along with models needed to interpret…”
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Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols by Weber, Patrick, Nasseri, Seyed A, Pabst, Bettina M, Torvisco, Ana, Müller, Philipp, Paschke, Eduard, Tschernutter, Marion, Windischhofer, Werner, Withers, Stephen G, Wrodnigg, Tanja M, Stütz, Arnold E

“…From 1,2;3,4-di- -isopropylidene-d-galactopyranose, a preliminary series of highly functionalized amino(hydroxymethyl)cyclopentanes was easily available. These…”
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