Search Results - "Pabla, Navjot S"

Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury by Rauckhorst, Adam J, Vasquez Martinez, Gabriela, Mayoral Andrade, Gabriel, Wen, Hsiang, Kim, Ji Young, Simoni, Aaron, Robles-Planells, Claudia, Mapuskar, Kranti A, Rastogi, Prerna, Steinbach, Emily J, McCormick, Michael L, Allen, Bryan G, Pabla, Navjot S, Jackson, Ashley R, Coleman, Mitchell C, Spitz, Douglas R, Taylor, Eric B, Zepeda-Orozco, Diana

“…Energy-intensive kidney reabsorption processes essential for normal whole-body function are maintained by tubular epithelial cell metabolism. Although tubular…”
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IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in acute kidney injury by Taguchi, Kensei, Sugahara, Sho, Elias, Bertha C, Pabla, Navjot S, Canaud, Guillaume, Brooks, Craig R

“…Acute kidney injury (AKI) affects over 13 million people worldwide annually and is associated with a 4-fold increase in mortality. Our lab and others have…”
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Genome-Wide CRISPR Screen Identifies Phospholipid Scramblase 3 as the Biological Target of Mitoprotective Drug SS-31 by Silvaroli, Josie A, Bisunke, Bijay, Kim, Ji Young, Stayton, Amanda, Jayne, Laura A, Martinez, Shirely A, Nguyen, Christopher, Patel, Prisha S, Vanichapol, Thitinee, Verma, Vivek, Akhter, Juheb, Bolisetty, Subhashini, Madhavan, Sethu M, Kuscu, Cem, Coss, Christopher C, Zepeda-Orozco, Diana, Parikh, Samir V, Satoskar, Anjali A, Davidson, Alan J, Eason, James D, Szeto, Hazel H, Pabla, Navjot S, Bajwa, Amandeep

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Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2 by Bashore, Frances M., Min, Sophia M., Chen, Xiangrong, Howell, Stefanie, Rinderle, Caroline H., Morel, Gabriel, Silvaroli, Josie A., Wells, Carrow I., Bunnell, Bruce A., Drewry, David H., Pabla, Navjot S., Ultanir, Sila K., Bullock, Alex N., Axtman, Alison D.

“…Acylaminoindazole-based inhibitors of CDKL2 were identified via analyses of cell-free binding and selectivity data. Compound 9 was selected as a CDKL2 chemical…”
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Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective by Ong, Han Wee, Liang, Yi, Richardson, William, Lowry, Emily R., Wells, Carrow I., Chen, Xiangrong, Silvestre, Margaux, Dempster, Kelvin, Silvaroli, Josie A., Smith, Jeffery L., Wichterle, Hynek, Pabla, Navjot S., Ultanir, Sila K., Bullock, Alex N., Drewry, David H., Axtman, Alison D.

“…Despite mediating several essential processes in the brain, including during development, cyclin-dependent kinase-like 5 (CDKL5) remains a poorly characterized…”
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