Search Results - "Pabit, Suzette A"

Determining the Locations of Ions and Water around DNA from X-Ray Scattering Measurements by Meisburger, Steve P., Pabit, Suzette A., Pollack, Lois

“…Nucleic acids carry a negative charge, attracting salt ions and water. Interactions with these components of the solvent drive DNA to condense, RNA to fold,…”
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Ionic strength-dependent persistence lengths of single-stranded RNA and DNA by Chen, Huimin, Meisburger, Steve P, Pabit, Suzette A, Sutton, Julie L, Webb, Watt W, Pollack, Lois

“…Dynamic RNA molecules carry out essential processes in the cell including translation and splicing. Base-pair interactions stabilize RNA into relatively rigid…”
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Asymmetric unwrapping of nucleosomal DNA propagates asymmetric opening and dissociation of the histone core by Chen, Yujie, Tokuda, Joshua M., Topping, Traci, Meisburger, Steve P., Pabit, Suzette A., Gloss, Lisa M., Pollack, Lois

“…The nucleosome core particle (NCP) is the basic structural unit for genome packaging in eukaryotic cells and consists of DNA wound around a core of eight…”
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RNA and Its Ionic Cloud: Solution Scattering Experiments and Atomically Detailed Simulations by Kirmizialtin, Serdal, Pabit, Suzette A., Meisburger, Steve P., Pollack, Lois, Elber, Ron

“…RNA molecules play critical roles in many cellular processes. Traditionally viewed as genetic messengers, RNA molecules were recently discovered to have…”
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The Role of Correlation and Solvation in Ion Interactions with B-DNA by Sushko, Maria L., Thomas, Dennis G., Pabit, Suzette A., Pollack, Lois, Onufriev, Alexey V., Baker, Nathan A.

“…The ionic atmospheres around nucleic acids play important roles in biological function. Large-scale explicit solvent simulations coupled to experimental assays…”
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Chaotic advection mixer for capturing transient states of diverse biological macromolecular systems with time-resolved small-angle X-ray scattering by Zielinski, Kara A, Katz, Andrea M, Calvey, George D, Pabit, Suzette A, Milano, Shawn K, Aplin, Cody, San Emeterio, Josue, Cerione, Richard A, Pollack, Lois

“…Advances in time-resolved structural techniques, mainly in macromolecular crystallography and small-angle X-ray scattering (SAXS), allow for a detailed view of…”
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Recognition of Polyadenosine RNA by Zinc Finger Proteins by Kelly, Seth M., Pabit, Suzette A., Kitchen, Chad M., Guo, Peng, Marfatia, Kavita A., Murphy, T. J., Corbett, Anita H., Berland, Keith M.

“…Messenger RNA transcripts are coated from cap to tail with a dynamic combination of RNA binding proteins that process, package, and ultimately regulate the…”
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Mono- and Trivalent Ions around DNA: A Small-Angle Scattering Study of Competition and Interactions by Andresen, Kurt, Qiu, Xiangyun, Pabit, Suzette A., Lamb, Jessica S., Park, Hye Yoon, Kwok, Lisa W., Pollack, Lois

“…The presence of small numbers of multivalent ions in DNA-containing solutions results in strong attractive forces between DNA strands. Despite the biological…”
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Internal Friction Controls the Speed of Protein Folding from a Compact Configuration by Pabit, Suzette A, Roder, Heinrich, Hagen, Stephen J

“…Several studies have found millisecond protein folding reactions to be controlled by the viscosity of the solvent:  Reducing the viscosity allows folding to…”
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Closing the lid on DNA end-to-end stacking interactions by Li, Li, Pabit, Suzette A., Lamb, Jessica S., Park, Hye Yoon, Pollack, Lois

“…Recent experiments suggest that short DNA strands associate by end-to-end stacking. Here, we report interactions between DNAs with modified ends. DNA duplexes,…”
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Contrast variation SAXS: Sample preparation protocols, experimental procedures, and data analysis by San Emeterio, Josue, Pabit, Suzette A, Pollack, Lois

“…Proteins and nucleic acids, alone and in complex are among the essential building blocks of living organisms. Obtaining a molecular level understanding of…”
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Spermine Condenses DNA, but Not RNA Duplexes by Katz, Andrea M., Tolokh, Igor S., Pabit, Suzette A., Baker, Nathan, Onufriev, Alexey V., Pollack, Lois

“…Interactions between the polyamine spermine and nucleic acids drive important cellular processes. Spermine condenses DNA and some RNAs, such as…”
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Divalent ions tune the kinetics of a bacterial GTPase center rRNA folding transition from secondary to tertiary structure by Welty, Robb, Pabit, Suzette A, Katz, Andrea M, Calvey, George D, Pollack, Lois, Hall, Kathleen B

“…Folding of an RNA from secondary to tertiary structure often depends on divalent ions for efficient electrostatic charge screening (nonspecific association) or…”
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Why double-stranded RNA resists condensation by Tolokh, Igor S, Pabit, Suzette A, Katz, Andrea M, Chen, Yujie, Drozdetski, Aleksander, Baker, Nathan, Pollack, Lois, Onufriev, Alexey V

“…The addition of small amounts of multivalent cations to solutions containing double-stranded DNA leads to inter-DNA attraction and eventual condensation…”
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Revealing transient structures of nucleosomes as DNA unwinds by Chen, Yujie, Tokuda, Joshua M, Topping, Traci, Sutton, Julie L, Meisburger, Steve P, Pabit, Suzette A, Gloss, Lisa M, Pollack, Lois

“…The modulation of DNA accessibility by nucleosomes is a fundamental mechanism of gene regulation in eukaryotes. The nucleosome core particle (NCP) consists of…”
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Structural analyses of an RNA stability element interacting with poly(A) by Torabi, Seyed-Fakhreddin, Chen, Yen-Lin, Zhang, Kaiming, Wang, Jimin, DeGregorio, Suzanne J., Vaidya, Anand T., Su, Zhaoming, Pabit, Suzette A., Chiu, Wah, Pollack, Lois, Steitz, Joan A.

“…Cis-acting RNA elements are crucial for the regulation of polyadenylated RNA stability. The element for nuclear expression (ENE) contains a U-rich internal…”
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Double-stranded RNA resists condensation by Li, Li, Pabit, Suzette A, Meisburger, Steve P, Pollack, Lois

“…Much attention has been focused on DNA condensation because of its fundamental biological importance. The recent discovery of new roles for RNA duplexes…”
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Elucidating the Role of Microprocessor Protein DGCR8 in Bending RNA Structures by Pabit, Suzette A., Chen, Yen-Lin, Usher, Emery T., Cook, Erik C., Pollack, Lois, Showalter, Scott A.

“…Although conformational dynamics of RNA molecules are potentially important in microRNA (miRNA) processing, the role of the protein binding partners in…”
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Extracting water and ion distributions from solution x-ray scattering experiments by Nguyen, Hung T, Pabit, Suzette A, Pollack, Lois, Case, David A

“…Small-angle X-ray scattering measurements can provide valuable information about the solvent environment around biomolecules, but it can be difficult to…”
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Counting Ions around DNA with Anomalous Small-Angle X-ray Scattering by Pabit, Suzette A, Meisburger, Steve P, Li, Li, Blose, Joshua M, Jones, Christopher D, Pollack, Lois

“…The majority of charge-compensating ions around nucleic acids form a diffuse counterion “cloud” that is not amenable to investigation by traditional methods…”
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