Search Results - "Pańczyk, K."

Design, synthesis and cardiovascular evaluation of some aminoisopropanoloxy derivatives of xanthone by Kubacka, M., Szkaradek, N., Mogilski, S., Pańczyk, K., Siwek, A., Gryboś, A., Filipek, B., Żmudzki, P., Marona, H., Waszkielewicz, A.M.

“…[Display omitted] •We synthesized 8 derivatives of xanthone with structural elements of known drugs.•We evaluated cardiovascular activity of the tested…”
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Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system by Pańczyk, Katarzyna, Pytka, Karolina, Jakubczyk, Magdalena, Rapacz, Anna, Sałat, Kinga, Furgała, Anna, Siwek, Agata, Głuch-Lutwin, Monika, Gryboś, Anna, Słoczyńska, Karolina, Pękala, Elżbieta, Żmudzki, Paweł, Bucki, Adam, Kołaczkowski, Marcin, Żelaszczyk, Dorota, Marona, Henryk, Waszkielewicz, Anna M.

“…[Display omitted] •Presented compounds possess mainly antagonistic activity for serotonergic receptors.•Compound 9 showed 5-HT1A Ki = 5 nM, 5-HT7 Ki = 70 nM,…”
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