Search Results - "Pañeda, C."
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1
SYL040012, a siRNA for the treatment of glaucoma
Published in Acta ophthalmologica (Oxford, England) (01-08-2013)“…Purpose SYL040012 is a siRNA under developed for the treatment of glaucoma and increased intraocular pressure (IOP). siRNAs are small double stranded RNAs that…”
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2
Growth Hormone-Releasing Peptide-6 Increases Insulin-Like Growth Factor-I mRNA Levels and Activates Akt in RCA-6 Cells as a Model of Neuropeptide Y Neurones
Published in Journal of neuroendocrinology (01-11-2005)“…Chronic systemic administration of growth hormone (GH)‐releasing peptide‐6 (GHRP‐6), an agonist for the ghrelin receptor, to normal adult rats increases…”
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3
Role of diffusible and transcription factors in inner ear development: implications in regeneration
Published in Histology and histopathology (01-04-2000)“…Organogenesis involves a dynamic balance of the mechanisms regulating cell division, differentiation and death. The development of the chicken embryo inner ear…”
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4
The corticotropin-releasing factor-hypocretin connection: implications in stress response and addiction
Published in Drug news & perspectives (01-05-2005)“…The hypothalamic neuropeptides hypocretins (orexins) play a crucial role in the stability of arousal and alertness. Recent data have raised the hypothesis that…”
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5
The number of lactotrophs is reduced in the anterior pituitary of streptozotocin-induced diabetic rats
Published in Diabetologia (01-05-2003)“…Prolactin secretion is often reduced in insulin dependent diabetes mellitus, but little is known about the mechanism involved. Since changes in the hormonal…”
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6
Short-chain ceramide regulates hepatic methionine adenosyltransferase expression
Published in Journal of hepatology (01-02-2001)“…Background : The metabolism of methionine plays an important role in regulating hepatic cellular function. Methionine adenosyltransferase (MAT) is the enzyme…”
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7
Purification and characterization of insulin-mimetic inositol phosphoglycan-like molecules from grass pea (Lathyrus sativus) seeds
Published in Molecular medicine (Cambridge, Mass.) (01-07-2001)“…Signal transduction through the hydrolysis of glycosyl-phosphatidylinositol (GPI) leading to the release of the water-soluble inositol phosphoglycan (IPG)…”
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8
Towards the in vitro reconstitution of caveolae. Asymmetric incorporation of glycosylphosphatidylinositol (GPI) and gangliosides into liposomal membranes
Published in FEBS letters (20-08-1999)“…Large unilamellar vesicles consisting of phospholipids with or without cholesterol have been prepared containing GPI and/or gangliosides asymmetrically located…”
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9
Growth Hormone (GH) and GH-Releasing Peptide-6 Increase Brain Insulin-Like Growth Factor-I Expression and Activate Intracellular Signaling Pathways Involved in Neuroprotection
Published in Endocrinology (Philadelphia) (01-10-2002)“…Beneficial effects of GH on memory, mental alertness, and motivation have been documented. Many actions of GH are mediated through IGF-I; hence, we…”
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10
Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6‐methyl‐phenyl‐tetrahydropyridine toxicity
Published in Journal of neurochemistry (01-04-2005)“…Oxidative stress is implicated in the death of dopaminergic neurons in sporadic forms of Parkinson's disease. Because oxidative stress can be modulated…”
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11
Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis
Published in The Journal of clinical investigation (01-03-2004)“…S-adenosyl-L-methionine (SAM) is synthesized by methionine adenosyltransferases (MATs). Ablation of the liver-specific MAT1A gene results in liver neoplasia…”
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12
Liver cell proliferation requires methionine adenosyltransferase 2A mRNA up-regulation
Published in Hepatology (Baltimore, Md.) (01-06-2002)“…Regulation of liver cell proliferation is a key event to control organ size during development and liver regeneration. Methionine adenosyltransferase (MAT) 2A…”
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13
Growth hormone-releasing peptide-6 inhibits cerebellar cell death in aged rats
Published in Neuroreport (26-08-2003)“…Insulin-like growth factor (IGF)-I is essential for cerebellar granule neuron survival and a decline in IGF-I is implicated in various age-dependent processes…”
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14
Phosphorylation of glycosyl-phosphatidylinositol by phosphatidylinositol 3-kinase changes its properties as a substrate for phospholipases
Published in FEBS letters (03-01-2005)“…Phosphatidylinositol 3-kinases (PI3K) phosphorylate the 3-position of the inositol ring of phosphatidylinositol-4,5-bisphosphate to produce…”
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15
Development of a poly-gate NMOS process for research and teaching
Published in Proceedings Ninth Biennial University/Government/Industry Microelectronics Symposium (1991)“…An integrated circuit fabrication facility has been developed at the University of Florida which is suitable for undergraduate laboratories, research in…”
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