Search Results - "PURCHIO, Tony"

Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis by Jenkins, Darlene E, Oei, Yoko, Hornig, Yvette S, Yu, Shang-Fan, Dusich, Joan, Purchio, Tony, Contag, Pamela R

“…Bioluminescent imaging (BLI) permits sensitive in vivo detection and quantification of cells specifically engineered to emit visible light. Three stable human…”
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Visualizing pneumococcal infections in the lungs of live mice using bioluminescent Streptococcus pneumoniae transformed with a novel gram-positive lux transposon by FRANCIS, Kevin P, JUN YU, BELLINGER-KAWAHARA, Carolyn, JOH, Danny, HAWKINSON, Matthew J, XIAO, Grace, PURCHIO, Tony F, CAPARON, Michael G, LIPSITCH, Marc, CONTAG, Pamela R

“…Animal studies with Streptococcus pneumoniae have provided valuable models for drug development. In order to monitor long-term pneumococcal infections…”
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Reduction of Astrogliosis by Early Treatment of Pneumococcal Meningitis Measured by Simultaneous Imaging, In Vivo, of the Pathogen and Host Response by Kadurugamuwa, Jagath L, Modi, Kshitij, Coquoz, Olivier, Rice, Brad, Smith, Steven, Contag, Pamela R, Purchio, Tony

“…We developed a method for simultaneous in vivo biophotonic monitoring of pneumococcal meningitis and the accompanying neuronal injury in live transgenic mice…”
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Rapid Direct Method for Monitoring Antibiotics in a Mouse Model of Bacterial Biofilm Infection by KADURUGAMUWA, Jagath L, SIN, Lin V, JUN YU, FRANCIS, Kevin P, KIMURA, Richard, PURCHIO, Tony, CONTAG, Pamela R

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Noninvasive Biophotonic Imaging for Monitoring of Catheter-Associated Urinary Tract Infections and Therapy in Mice by Kadurugamuwa, Jagath L, Modi, Kshitij, Yu, Jun, Francis, Kevin P, Purchio, Tony, Contag, Pamela R

“…Urinary tract infections (UTIs) are among the most common bacterial infections acquired by humans, particularly in catheterized patients. A major problem with…”
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Noninvasive Optical Imaging Method To Evaluate Postantibiotic Effects on Biofilm Infection In Vivo by KADURUGAMUWA, Jagath L, SIN, Lin V, JUN YU, FRANCIS, Kevin P, PURCHIO, Tony F, CONTAG, Pamela R

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Monitoring in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm infection model by Yu, Jun, Wu, Jenny, Francis, Kevin P., Purchio, Tony F., Kadurugamuwa, Jagath L.

“…Objectives: To investigate in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm model using bioluminescence imaging…”
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In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer by Jenkins, Darlene E, Yu, Shang-Fan, Hornig, Yvette S, Purchio, Tony, Contag, Pamela R

“…We used the bioluminescent human prostate carcinoma cell line PC-3M-luc-C6 to non-invasively monitor in vivo growth and response of tumors and metastasis…”
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Imaging of bioluminescent LNCaP-luc-M6 Tumors: A new animal model for the study of metastatic human prostate cancer by Scatena, Caroline D., Hepner, Mischa A., Oei, Yoko A., Dusich, Joan M., Yu, Shang-Fan, Purchio, Tony, Contag, Pamela R., Jenkins, Darlene E.

“…BACKGROUND Animal experiments examining hormone‐sensitive metastatic prostate cancer using the human LNCaP cell line have been limited to endpoint analyses. To…”
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Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice by Jenkins, Darlene E, Hornig, Yvette S, Oei, Yoko, Dusich, Joan, Purchio, Tony

“…Our goal was to generate xenograft mouse models of human breast cancer based on luciferase-expressing MDA-MB-231 tumor cells that would provide rapid mammary…”
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Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDE construct by FRANCIS, K. P, JOH, D, BELLINGER-KAWAHARA, C, HAWKINSON, M. J, PURCHIO, T. F, CONTAG, P. R

“…Strains of Staphylococcus aureus were transformed with plasmid DNA containing a Photorhabdus luminescens lux operon (luxABCDE) that was genetically modified to…”
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Noninvasive bioluminescence imaging of normal and spontaneously transformed prostate tissue in mice by LYONS, Scott K, LIM, Ed, JENKINS, Darlene, CLERMONT, Anne O, DUSICH, Joan, LINGYUN ZHU, CAMPBELL, Kenneth D, COFFEE, Richard J, GRASS, David S, HUNTER, John, PURCHIO, Tony

“…Several transgenic mouse models of prostate cancer have been developed recently that are able to recapitulate many key biological features of the human…”
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Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivodetection of mammary tumors and multiple metastases in immune deficient mice by Jenkins, Darlene E, Hornig, Yvette S, Oei, Yoko, Dusich, Joan, Purchio, Tony

“…Abstract Introduction Our goal was to generate xenograft mouse models of human breast cancer based on luciferase-expressing MDA-MB-231 tumor cells that would…”
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Monitoring Bioluminescent Staphylococcus aureusInfections in Living Mice Using a Novel luxABCDEConstruct by Kevin P. Francis, Danny Joh, Carolyn Bellinger-Kawahara, Matthew J. Hawkinson, Tony F. Purchio, Pamela R. Contag

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Visualizing Pneumococcal Infections in the Lungs of Live Mice Using Bioluminescent Streptococcus pneumoniaeTransformed with a Novel Gram-Positive luxTransposon by Kevin P. Francis, Jun Yu, Carolyn Bellinger-Kawahara, Danny Joh, Matthew J. Hawkinson, Grace Xiao, Tony F. Purchio, Michael G. Caparon, Marc Lipsitch, Pamela R. Contag

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