Search Results - "PUOPOLO, Manuela"
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ERCC1 Genotype and Phenotype in Epithelial Ovarian Cancer Identify Patients Likely to Benefit From Paclitaxel Treatment in Addition to Platinum-Based Therapy
Published in Journal of clinical oncology (20-11-2007)“…To investigate the effect of excision repair cross-complementation group 1 (ERCC1) on treatment response and survival of patients treated with platinum…”
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The relationship of insulin-like growth factor-II, insulin-like growth factor binding protein-3, and estrogen receptor-alpha expression to disease progression in epithelial ovarian cancer
Published in Clinical cancer research (15-02-2006)“…PURPOSE: The insulin-like growth factor (IGF) system plays important roles in cancer; blocking IGF signaling has been shown to have therapeutic effects on…”
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Prognostic Value of the Human Kallikrein Gene 15 Expression in Ovarian Cancer
Published in Journal of clinical oncology (15-08-2003)“…KLK15 is a newly cloned human kallikrein gene. Many kallikreins were found to be differentially expressed in ovarian cancer. Like other kallikreins, KLK15 is…”
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Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer
Published in American journal of clinical pathology (01-03-2003)“…To study KLK14 gene expression in endocrine-related cancers, we studied its hormonal regulation in breast and ovarian cancer cell lines. Our kinetic and…”
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Aberrant promoter methylation of multiple genes in malignant ovarian tumors and in ovarian tumors with low malignant potential
Published in Cancer (15-07-2006)“…BACKGROUND. Methylation‐mediated suppression of detoxification, DNA repair, and tumor suppressor genes has been implicated in cancer development and…”
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Klotho Expression in Epithelial Ovarian Cancer and its Association with Insulin-Like Growth Factors and Disease Progression
Published in Cancer investigation (01-01-2008)“…Klotho is an anti-aging hormone and is able to suppress the action of IGFs. High IGF activities are associated with cancer risk and tumor progression. Klotho's…”
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Promoter-specific transcription of insulin-like growth factor-II in epithelial ovarian cancer
Published in Gynecologic oncology (01-12-2006)“…The IGF-II gene has four promoters (P1–P4); each initiates promoter-specific transcription. Studies have shown that IGF-II promoters normally active during…”
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Expression of MDR1 in epithelial ovarian cancer and its association with disease progression
Published in Oncology research (01-01-2007)“…The purposes of this study were to analyze MDR1 expression in ovarian tumors prior to chemotherapy, to correlate the expression with p16, IGFs, ERalpha, and…”
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Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma
Published in International journal of cancer (10-09-2003)“…Human kallikrein 11 (hK11/trypsin‐like serine protease/TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases…”
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