Search Results - "PULLIAM, L"
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Enhancing Activity Recognition After Stroke: Generative Adversarial Networks for Kinematic Data Augmentation
Published in Sensors (Basel, Switzerland) (25-10-2024)“…The generalizability of machine learning (ML) models for wearable monitoring in stroke rehabilitation is often constrained by the limited scale and…”
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2
Nanoparticles for drug delivery to the lungs
Published in Trends in biotechnology (Regular ed.) (01-12-2007)“…The lungs are an attractive route for non-invasive drug delivery with advantages for both systemic and local applications. Incorporating therapeutics with…”
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3
Updated research nosology for HIV-associated neurocognitive disorders
Published in Neurology (30-10-2007)“…In 1991, the AIDS Task Force of the American Academy of Neurology published nomenclature and research case definitions to guide the diagnosis of neurologic…”
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4
The Gene Expression Signatures of Melanoma Progression
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2005)“…Because of the paucity of available tissue, little information has previously been available regarding the gene expression profiles of primary melanomas. To…”
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5
Electromyogram-based neural network control of transhumeral prostheses
Published in Journal of rehabilitation research and development (01-01-2011)“…Upper-limb amputation can cause a great deal of functional impairment for patients, particularly for those with amputation at or above the elbow. Our long-term…”
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6
Motion sensor strategies for automated optimization of deep brain stimulation in Parkinson's disease
Published in Parkinsonism & related disorders (01-04-2015)“…Abstract Background Deep brain stimulation (DBS) is a well-established treatment for Parkinson's disease (PD). Optimization of DBS settings can be a challenge…”
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CIRCUMSTELLAR ION-MOLECULE CHEMISTRY: OBSERVATIONS OF HCO+ IN THE ENVELOPES OF O-RICH STARS AND IRC + 10216
Published in The Astrophysical journal (10-12-2011)“…Millimeter-wave observations of HCO+ have been conducted toward oxygen-rich circumstellar envelopes, as well as IRC+10216, using the facilities of the Arizona…”
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Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer
Published in Cells (Basel, Switzerland) (10-06-2022)“…Despite early studies linking calcium-calmodulin protein kinase kinase 2 (CAMKK2) to prostate cancer cell migration and invasion, the role of CAMKK2 in…”
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SGC-CAMKK2-1: A Chemical Probe for CAMKK2
Published in Cells (Basel, Switzerland) (11-01-2023)“…The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes…”
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10
Biomarkers of HIV-1 CNS infection and injury
Published in Neurology (30-10-2007)“…While it is clear that HIV-1 can cause CNS dysfunction, current approaches to classification and diagnosis of this dysfunction rely on syndromic definitions or…”
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11
Continuous in-home monitoring of essential tremor
Published in Parkinsonism & related disorders (01-01-2014)“…Abstract Background Essential tremor (ET) is typically measured in the clinic with subjective tremor rating scales which require the presence of a clinician…”
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Regulation and role of CAMKK2 in prostate cancer
Published in Nature reviews. Urology (01-06-2022)“…In 2011, CAMKK2 , the gene encoding calcium/calmodulin-dependent kinase kinase 2 (CAMKK2), was demonstrated to be a direct target of the androgen receptor and…”
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Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling
Published in Oncogene (04-03-2021)“…Previous work has suggested androgen receptor (AR) signaling mediates prostate cancer progression in part through the modulation of autophagy. However,…”
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14
GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling
Published in Endocrine-related cancer (01-04-2018)“…Despite altered metabolism being an accepted hallmark of cancer, it is still not completely understood which signaling pathways regulate these processes. Given…”
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A SEARCH FOR HYDROXYLAMINE (NH2OH) TOWARD SELECT ASTRONOMICAL SOURCES
Published in The Astrophysical journal (20-05-2012)“…Observations of 14 rotational transitions of hydroxylamine (NH{sub 2}OH) using the NRAO 12 m telescope on Kitt Peak are reported toward IRC+10216, Orion KL,…”
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16
Carbon Chemistry in the Envelope of VY Canis Majoris: Implications for Oxygen-Rich Evolved Stars
Published in The Astrophysical journal (20-04-2009)“…Observations of the carbon-bearing molecules CO, HCN, CS, HNC, CN, and HCO+ have been conducted toward the circumstellar envelope of the oxygen-rich red…”
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Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity
Published in Cancer research (Chicago, Ill.) (04-03-2024)“…Lipid metabolism plays a central role in prostate cancer. To date, the major focus has centered on de novo lipogenesis and lipid uptake in prostate cancer, but…”
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18
Fungal Keratitis in a Critically Ill Post-trauma Patient
Published in Curēus (Palo Alto, CA) (01-08-2023)“…Keratitis is the leading cause of corneal blindness in the world. Nearly half the cases are due to a fungal infection known as fungal keratitis (FK). There is…”
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Gene Expression, Bacteria Viability and Survivability Following Spray Drying of Mycobacterium smegmatis
Published in Materials (01-04-2010)“…We find that Mycobacterium smegmatis survives spray drying and retains cell viability in accelerated temperature stress (40 °C) conditions with a success rate…”
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Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes
Published in Journal of medicinal chemistry (12-08-2021)“…CAMKK2 is a serine/threonine kinase and an activator of AMPK whose dysregulation is linked with multiple diseases. Unfortunately, STO-609, the tool inhibitor…”
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