Search Results - "PUCCI, Sabina"

Pro-oncogenic action of LOX-1 and its splice variant LOX-1Δ4 in breast cancer phenotypes by Pucci, Sabina, Polidoro, Chiara, Greggi, Chiara, Amati, Francesca, Morini, Elena, Murdocca, Michela, Biancolella, Michela, Orlandi, Augusto, Sangiuolo, Federica, Novelli, Giuseppe

“…The identification of new predictive biomarkers and therapeutic target for tailored therapy in breast cancer onset and progression is an interesting challenge…”
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Modulation of different clusterin isoforms in human colon tumorigenesis by PUCCI, Sabina, BONANNO, Elena, PICHIORRI, Flavia, ANGELONI, Caterina, SPAGNOLI, Luigi Giusto

“…Clusterin is a ubiquitous secretory heterodimeric disulfide-linked glycoprotein, which is implicated in several physiological processes, including immune…”
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Targeting LOX-1 Inhibits Colorectal Cancer Metastasis in an Animal Model by Murdocca, Michela, Capuano, Rosamaria, Pucci, Sabina, Cicconi, Rosella, Polidoro, Chiara, Catini, Alexandro, Martinelli, Eugenio, Paolesse, Roberto, Orlandi, Augusto, Mango, Ruggiero, Novelli, Giuseppe, Di Natale, Corrado, Sangiuolo, Federica

“…Recurrence and metastasis are the primary causes of mortality in patients with colorectal cancer (CRC), and therefore effective tools to reduce morbidity and…”
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The lectin-like oxidized LDL receptor-1: a new potential molecular target in colorectal cancer by Murdocca, Michela, Mango, Ruggiero, Pucci, Sabina, Biocca, Silvia, Testa, Barbara, Capuano, Rosamaria, Paolesse, Roberto, Sanchez, Massimo, Orlandi, Augusto, di Natale, Corrado, Novelli, Giuseppe, Sangiuolo, Federica

“…The identification of new biomarkers and targets for tailored therapy in human colorectal cancer (CRC) onset and progression is an interesting challenge. CRC…”
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Modulation of Carnitine Palmitoyl Transferase 1b Expression and Activity in Muscle Pathophysiology in Osteoarthritis and Osteoporosis by Greggi, Chiara, Montanaro, Manuela, Scioli, Maria Giovanna, Puzzuoli, Martina, Gino Grillo, Sonia, Scimeca, Manuel, Mauriello, Alessandro, Orlandi, Augusto, Gasbarra, Elena, Iundusi, Riccardo, Pucci, Sabina, Tarantino, Umberto

“…In the pathophysiology of osteoarthritis and osteoporosis, articular cartilage and bone represent the target tissues, respectively, but muscle is also…”
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The human rs1050286 polymorphism alters LOX‐1 expression through modifying miR‐24 binding by Morini, Elena, Rizzacasa, Barbara, Pucci, Sabina, Polidoro, Chiara, Ferrè, Fabrizio, Caporossi, Daniela, Helmer Citterich, Manuela, Novelli, Giuseppe, Amati, Francesca

“…The up‐regulation of lectin‐like oxidized low‐density lipoprotein receptor‐1 (LOX‐1), encoded by the OLR1 gene, plays a fundamental role in the pathogenesis of…”
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Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression by Floris, Andrea, Luo, Jia, Frank, Jacqueline, Zhou, Jennifer, Orrù, Sandro, Biancolella, Michela, Pucci, Sabina, Orlandi, Augusto, Campagna, Paolo, Balzano, Antonella, Ramani, Komal, Tomasi, Maria Lauda

“…Ethanol abuse promotes breast cancer development, metastasis and recurrence stimulating mammary tumorigenesis by mechanisms that remain unclear. Normally, 35%…”
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Exon-skipping strategy by ratio modulation between cytoprotective versus pro-apoptotic clusterin forms increased sensitivity of LNCaP to cell death by Essabbani, Abdellatif, Garcia, Luis, Zonetti, Maria Josè, Fisco, Tommaso, Pucci, Sabina, Chiocchia, Gilles

“…In prostate cancer the secreted form of clusterin (sCLU) has been described as an anti-apoptotic protein whose expression is increased after therapeutic…”
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Early Hippocampal i-LTP and LOX-1 Overexpression Induced by Anoxia: A Potential Role in Neurodegeneration in NPC Mouse Model by Lo Castro, Adriana, Murdocca, Michela, Pucci, Sabina, Zaratti, Anna, Greggi, Chiara, Sangiuolo, Federica, Tancredi, Virginia, Frank, Claudio, D'Arcangelo, Giovanna

“…Niemann-Pick type C disease (NPCD) is an autosomal recessive storage disorder, characterized by abnormal sequestration of unesterified cholesterol within the…”
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Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression by Pucci, Sabina, Mazzarelli, Paola, Sesti, Fabiola, Boothman, David A., Spagnoli, Luigi G.

“…Activation of pro-survival pathways and apoptotic cell death escape are considered hallmarks of oncogenic cell transformation. Tissue microenvironment strongly…”
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Cytokines and Disease by Orzechowski, Arkadiusz, Rostagno, Agueda A., Pucci, Sabina, Chiocchia, Gilles

“…According to current knowledge, several drugs counteracting TGF- β 1 have been developed and are either in preclinical or in early stages of clinical…”
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Carnitine palmitoyltransferase I in human carcinomas: A novel role in histone deacetylation? by Mazzarelli, Paola, Pucci, Sabina, Bonanno, Elena, Sesti, Fabiola, Calvani, Menotti, Giusto Spagnoli, Luigi

“…Carnitine palmitoyl transferase I (CPT1) catalyzes the transport of long-chain fatty acids into mitochondria for β-oxidation. A link between CPT1 and apoptosis…”
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Clusterin by Bettuzzi, Saverio, Pucci, Sabina

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Clusterin, Part B by Bettuzzi, Saverio, Pucci, Sabina

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Erratum to Sabina Pucci et al., Cell Cycle Volume 8, Issue 3; pp. 473-481 by Pucci, Sabina, Mazzarelli, Paola, Sesti, Fabiola, Boothman, David A., Spagnoli, Luigi G.

“…In the report "Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression" by Sabina…”
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Requirement of B- myb Function for Survival and Differentiative Potential of Human Neuroblastoma Cells by Raschell, Giuseppe, Negroni, Anna, Sala, Arturo, Pucci, Sabina, Romeo, Antonino, Calabretta, Bruno

“…The B- myb gene belongs to a family of transcription factors that also includes A- myb and c- myb. B- myb is expressed in many cell types including human…”
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LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies by Rizzacasa, Barbara, Morini, Elena, Pucci, Sabina, Murdocca, Michela, Novelli, Giuseppe, Amati, Francesca

“…Alternative splicing (AS) is a process in which precursor messenger RNA (pre-mRNA) splicing sites are differentially selected to diversify the protein isoform…”
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Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer by Pucci, Sabina, Zonetti, Maria Josè, Fisco, Tommaso, Polidoro, Chiara, Bocchinfuso, Gianfranco, Palleschi, Antonio, Novelli, Giuseppe, Spagnoli, Luigi G, Mazzarelli, Paola

“…Transcriptional mechanisms epigenetically-regulated in tumoral tissues point out new targets for anti-cancer therapies. Carnitine palmitoyl transferase I…”
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MicroRNA Dysregulation in Colon Cancer Microenvironment Interactions: The Importance of Small Things in Metastases by Pucci, Sabina, Mazzarelli, Paola

“…The influence of the microenvironment through the various steps of cancer progression is signed by different cytokines and growth factors, that could directly…”
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Clusterin exerts a cytoprotective and antioxidant effect in human osteoarthritic cartilage by Tarquini, Chiara, Pucci, Sabina, Scioli, Maria Giovanna, Doldo, Elena, Agostinelli, Sara, D'Amico, Federico, Bielli, Alessandra, Ferlosio, Amedeo, Caredda, Emanuele, Tarantino, Umberto, Orlandi, Augusto

“…Osteoarthritis (OA) is the most common joint disease characterized by destruction of articular cartilage. OA-induced cartilage degeneration causes…”
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